2VME
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![BU of 2vme by Molmil](/molmil-images/mine/2vme) | Structure of the wild-type discoidin II from Dictyostelium discoideum | Descriptor: | CALCIUM ION, CHLORIDE ION, DISCOIDIN-2, ... | Authors: | Aragao, K.S, Satre, M, Imberty, A, Varrot, A. | Deposit date: | 2008-01-25 | Release date: | 2008-07-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure Determination of Discoidin II from Dictyostelium Discoideum and Carbohydrate Binding Properties of the Lectin Domain. Proteins, 73, 2008
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4TN4
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![BU of 4tn4 by Molmil](/molmil-images/mine/4tn4) | Crystal structure of ternary complex of Plasmodium vivax SHMT with glycine and a novel pyrazolopyran 33G: (4S)-6-amino-4-(5-cyano-3'-fluorobiphenyl-3-yl)-4-cyclobutyl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | Descriptor: | (4S)-6-amino-4-(5-cyano-3'-fluorobiphenyl-3-yl)-4-cyclobutyl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Witschel, M.C. | Deposit date: | 2014-06-03 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT): Cocrystal Structures of Pyrazolopyrans with Potent Blood- and Liver-Stage Activities. J.Med.Chem., 58, 2015
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2VM9
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![BU of 2vm9 by Molmil](/molmil-images/mine/2vm9) | Native structure of the recombinant discoidin II of Dictyostelium discoideum at 1.75 angstrom | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Aragao, K.S, Satre, M, Imberty, A, Varrot, A. | Deposit date: | 2008-01-24 | Release date: | 2008-07-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure Determination of Discoidin II from Dictyostelium Discoideum and Carbohydrate Binding Properties of the Lectin Domain. Proteins, 73, 2008
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1ZZE
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![BU of 1zze by Molmil](/molmil-images/mine/1zze) | X-ray Structure of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor | Descriptor: | Aldehyde reductase II, SULFATE ION | Authors: | Kamitori, S, Iguchi, A, Ohtaki, A, Yamada, M, Kita, K. | Deposit date: | 2005-06-14 | Release date: | 2005-09-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds J.Mol.Biol., 352, 2005
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1QJ6
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![BU of 1qj6 by Molmil](/molmil-images/mine/1qj6) | Novel Covalent Active Site Thrombin Inhibitors | Descriptor: | 6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID, HIRUGEN, THROMBIN | Authors: | Jhoti, H, Cleasby, A. | Deposit date: | 1999-06-22 | Release date: | 2000-06-22 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of Thrombin Complexed to a Novel Series of Synthetic Inhibitors Containing a 5,5-Trans-Lactone Template Biochemistry, 38, 1999
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4TTT
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![BU of 4ttt by Molmil](/molmil-images/mine/4ttt) | |
4S3R
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![BU of 4s3r by Molmil](/molmil-images/mine/4s3r) | |
2UUH
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![BU of 2uuh by Molmil](/molmil-images/mine/2uuh) | Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione | Descriptor: | DODECYL-ALPHA-D-MALTOSIDE, GLUTATHIONE, LEUKOTRIENE C4 SYNTHASE, ... | Authors: | Martinez Molina, D, Wetterholm, A, Kohl, A, McCarthy, A.A, Niegowski, D, Ohlson, E, Hammarberg, T, Eshaghi, S, Haeggstrom, J.Z, Nordlund, P. | Deposit date: | 2007-03-02 | Release date: | 2007-07-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase. Nature, 448, 2007
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2UV4
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![BU of 2uv4 by Molmil](/molmil-images/mine/2uv4) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | Authors: | Day, P, Sharff, A, PArra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | Deposit date: | 2007-03-09 | Release date: | 2007-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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1Q8D
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![BU of 1q8d by Molmil](/molmil-images/mine/1q8d) | The crystal structure of GDNF family co-receptor alpha 1 domain 3 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GDNF family receptor alpha 1 | Authors: | Leppanen, V.M, Bespalov, M.M, Runeberg-Roos, P, Puurand, U, Merits, A, Saarma, M, Goldman, A. | Deposit date: | 2003-08-21 | Release date: | 2004-08-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation. Embo J., 23, 2004
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4RQA
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![BU of 4rqa by Molmil](/molmil-images/mine/4rqa) | |
4TRC
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![BU of 4trc by Molmil](/molmil-images/mine/4trc) | Sulfolobus solfataricus adenine phosphoribosyltransferase with adenine | Descriptor: | ADENINE, PHOSPHATE ION, Purine phosphoribosyltransferase (GpT-1) | Authors: | Kadziola, A. | Deposit date: | 2014-06-16 | Release date: | 2014-07-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Adenine Phosphoribosyltransferase from Sulfolobus solfataricus Is an Enzyme with Unusual Kinetic Properties and a Crystal Structure that Suggests It Evolved from a 6-Oxopurine Phosphoribosyltransferase. Biochemistry, 54, 2015
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4TRN
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![BU of 4trn by Molmil](/molmil-images/mine/4trn) | STRUCTURE OF INHA FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED TO NADH | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, INHA, ... | Authors: | Chollet, A, Julien, S, Mourey, L, Maveyraud, L. | Deposit date: | 2014-06-17 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach. J.Struct.Biol., 190, 2015
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2XVG
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![BU of 2xvg by Molmil](/molmil-images/mine/2xvg) | crystal structure of alpha-xylosidase (GH31) from Cellvibrio japonicus | Descriptor: | 1,2-ETHANEDIOL, ALPHA XYLOSIDASE, CHLORIDE ION, ... | Authors: | Larsbrink, J, Izumi, A, Ibatullin, F, Nakhai, A, Gilbert, H.J, Davies, G.J, Brumer, H. | Deposit date: | 2010-10-26 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Enzymatic Characterisation of a Glycoside Hydrolase Family 31 Alpha-Xylosidase from Cellvibrio Japonicus Involved in Xyloglucan Saccharification. Biochem.J., 436, 2011
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4RUV
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![BU of 4ruv by Molmil](/molmil-images/mine/4ruv) | Crystal structure of thioredoxin 2 from Staphylococcus aureus NCTC8325 | Descriptor: | Thioredoxin | Authors: | Bose, M, Biswas, R, Roychowdhury, A, Bhattacharyya, S, Ghosh, A.K, Das, A.K. | Deposit date: | 2014-11-22 | Release date: | 2015-12-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight. Biochimie, 160, 2019
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2XH8
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![BU of 2xh8 by Molmil](/molmil-images/mine/2xh8) | X-ray structure of 119-141 ZnuA deletion mutant from Salmonella enterica. | Descriptor: | SODIUM ION, SULFATE ION, ZINC ABC TRANSPORTER, ... | Authors: | Alaleona, F, Ilari, A, Battistoni, A, Petrarca, P, Chiancone, E. | Deposit date: | 2010-06-09 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The X-Ray Structure of the Zinc Transporter Znua from Salmonella Enterica Discloses a Unique Triad of Zinc Coordinating Histidines. J.Mol.Biol., 409, 2011
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1Q6C
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![BU of 1q6c by Molmil](/molmil-images/mine/1q6c) | Crystal Structure of Soybean Beta-Amylase Complexed with Maltose | Descriptor: | SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-amylase | Authors: | Hirata, A, Adachi, M, Sekine, A, Kang, Y.N, Utsumi, S, Mikami, B. | Deposit date: | 2003-08-13 | Release date: | 2004-02-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural and Enzymatic Analysis of Soybean {beta}-Amylase Mutants with Increased pH Optimum J.Biol.Chem., 279, 2004
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2XQH
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![BU of 2xqh by Molmil](/molmil-images/mine/2xqh) | Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin EibD | Descriptor: | CHLORIDE ION, IMMUNOGLOBULIN-BINDING PROTEIN EIBD | Authors: | Leo, J.C, Lyskowski, A, Hartmann, M, Schwarz, H, Linke, D, Lupas, A.N, Goldman, A. | Deposit date: | 2010-09-02 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Structure of E. Coli Igg-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins. Structure, 19, 2011
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1DPJ
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![BU of 1dpj by Molmil](/molmil-images/mine/1dpj) | THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEINASE A, PROTEINASE INHIBITOR IA3 PEPTIDE, ... | Authors: | Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. | Deposit date: | 1999-12-27 | Release date: | 2000-05-03 | Last modified: | 2021-07-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
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2XFN
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![BU of 2xfn by Molmil](/molmil-images/mine/2xfn) | Human monoamine oxidase B in complex with 2-(2-benzofuranyl)-2- imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XY4
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![BU of 2xy4 by Molmil](/molmil-images/mine/2xy4) | X-RAY STRUCTURE OF ZNUA-WT FROM SALMONELLA ENTERICA | Descriptor: | SULFATE ION, TRIETHYLENE GLYCOL, ZINC ABC TRANSPORTER, ... | Authors: | Alaleona, F, Ilari, A, Battistoni, A, Petrarca, P, Chiancone, E. | Deposit date: | 2010-11-15 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The X-Ray Structure of the Zinc Transporter Znua from Salmonella Enterica Discloses a Unique Triad of Zinc Coordinating Histidines. J.Mol.Biol., 409, 2011
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4TRO
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![BU of 4tro by Molmil](/molmil-images/mine/4tro) | Structure of the enoyl-ACP reductase of Mycobacterium tuberculosis InhA, inhibited with the active metabolite of isoniazid | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | Authors: | Chollet, A, Julien, S, Mourey, L, Maveyraud, L. | Deposit date: | 2014-06-17 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach. J.Struct.Biol., 190, 2015
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2XFQ
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![BU of 2xfq by Molmil](/molmil-images/mine/2xfq) | Rasagiline-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | Descriptor: | (1R)-N-(prop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine, 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2UV5
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![BU of 2uv5 by Molmil](/molmil-images/mine/2uv5) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | Descriptor: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | Authors: | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | Deposit date: | 2007-03-09 | Release date: | 2007-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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1P7C
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![BU of 1p7c by Molmil](/molmil-images/mine/1p7c) | Crystal Structure of HSV1-TK complexed with TP5A | Descriptor: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, THYMIDINE, ... | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | Deposit date: | 2003-05-01 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
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