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4HS6
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BU of 4hs6 by Molmil
Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody MRCT10.v362
Descriptor: E2-peptide, MRCT10.v362 Fab heavy chain, MRCT10.v362 Fab light chain
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2012-10-29
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
J.Mol.Biol., 425, 2013
4HS8
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BU of 4hs8 by Molmil
Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody hu5B3.v3
Descriptor: E2-peptide, GLYCEROL, SULFATE ION, ...
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2012-10-29
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
J.Mol.Biol., 425, 2013
4NQU
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BU of 4nqu by Molmil
anti-parallel Fc-knob (T366W) homodimer
Descriptor: Ig gamma-1 chain C region, SULFATE ION
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2013-11-25
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction.
J.Mol.Biol., 426, 2014
4NQT
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BU of 4nqt by Molmil
anti-parallel Fc-hole(T366S/L368A/Y407V) homodimer
Descriptor: Ig gamma-1 chain C region
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2013-11-25
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction.
J.Mol.Biol., 426, 2014
4NQS
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BU of 4nqs by Molmil
Knob-into-hole IgG Fc
Descriptor: Ig gamma-1 chain C region, miniZ
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2013-11-25
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction.
J.Mol.Biol., 426, 2014
4GJJ
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BU of 4gjj by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with D-allopyranose
Descriptor: D-ALLOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
Authors:Yoshida, H, Kamitori, S.
Deposit date:2012-08-09
Release date:2012-12-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
4GJI
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BU of 4gji by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with L-rhamnopyranose
Descriptor: L-RHAMNOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
Authors:Yoshida, H, Kamitori, S.
Deposit date:2012-08-09
Release date:2012-12-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
5GKR
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BU of 5gkr by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide
Descriptor: DNA (5'-D(P*TP*TP*TP*T)-3'), IgG2, Fab (heavy chain), ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
5GKS
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BU of 5gks by Molmil
Crystal structure of SLE patient-derived anti-DNA antibody
Descriptor: IgG2, Fab (heavy chain), PHOSPHATE ION, ...
Authors:Arimori, T, Sakakibara, S, Kikutani, H, Takagi, J.
Deposit date:2016-07-05
Release date:2017-07-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus
Sci Rep, 7, 2017
7EA6
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BU of 7ea6 by Molmil
Crystal structure of TCR-017 ectodomain
Descriptor: T cell receptor 017 alpha chain, T cell receptor 017 beta chain
Authors:Nagae, M, Yamasaki, S.
Deposit date:2021-03-06
Release date:2021-10-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.18000245 Å)
Cite:Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.
J.Exp.Med., 218, 2021
3W2E
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BU of 3w2e by Molmil
Crystal structure of oxidation intermediate (20 min) of NADH-cytochrome b5 reductase from pig liver
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
3W2I
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BU of 3w2i by Molmil
Crystal structure of re-oxidized form (60 min) of NADH-cytochrome b5 reductase from pig liver
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
3W2F
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BU of 3w2f by Molmil
Crystal structure of oxidation intermediate (10 min) of NADH-cytochrome b5 reductase from pig liver
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
3W2G
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BU of 3w2g by Molmil
Crystal structure of fully reduced form of NADH-cytochrome b5 reductase from pig liver
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
3W2H
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BU of 3w2h by Molmil
Crystal structure of oxidation intermediate (1min) of NADH-cytochrome b5 reductase from pig liver
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yamada, M, Tamada, T, Matsumoto, F, Shoyama, Y, Kimura, S, Kuroki, R, Miki, K.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer
J.Mol.Biol., 425, 2013
2ZLB
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BU of 2zlb by Molmil
Crystal structure of APO form of rat catechol-O-methyltransferase
Descriptor: Catechol O-methyltransferase, SULFATE ION
Authors:Tsuji, E.
Deposit date:2008-04-04
Release date:2008-10-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase
J.Struct.Biol., 165, 2009
2ZVJ
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BU of 2zvj by Molmil
Crystal structures of rat Catechol-O-Methyltransferase complexed with coumarine-based inhibitor
Descriptor: 7,8-dihydroxy-4-phenyl-2H-chromen-2-one, Catechol O-methyltransferase, MAGNESIUM ION, ...
Authors:Tsuji, E.
Deposit date:2008-11-07
Release date:2009-01-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor
Biochem.Biophys.Res.Commun., 378, 2009
3ACJ
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BU of 3acj by Molmil
Crystal structure of imidazo pyrimidine derivative bound to the kinase domain of human LCK, (Auto-phosphorylated on TYR394)
Descriptor: 7-(3,4-dimethoxyphenyl)-5-(ethylsulfanyl)imidazo[1,2-c]pyrimidine, DIMETHYL SULFOXIDE, Proto-oncogene tyrosine-protein kinase LCK, ...
Authors:Tsuji, E.
Deposit date:2010-01-05
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3ACK
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BU of 3ack by Molmil
Crystal structure of Pyrrolo pyrazine derivative bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
Descriptor: 6-(5-methoxy-1-methyl-1H-indol-3-yl)-5H-pyrrolo[2,3-b]pyrazine, DIMETHYL SULFOXIDE, Proto-oncogene tyrosine-protein kinase LCK, ...
Authors:Tsuji, E.
Deposit date:2010-01-05
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3AD4
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BU of 3ad4 by Molmil
Crystal Structure of Methoxy Benzofuran Derivative bound to the Kinase domain of human LCK, (auto-phosphorylated on TYR394)
Descriptor: (4-chlorophenyl)(5-methoxy-1-benzofuran-2-yl)methanone, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ...
Authors:Tsuji, E.
Deposit date:2010-01-14
Release date:2011-01-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3AC1
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BU of 3ac1 by Molmil
Crystal structure of pyrazin derivative bound to the kinase domain of Human LCK, (Auto-phosphorylated on TYR394)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-{[(1R,2S)-2-aminocyclohexyl]amino}-3-[(3,5-dimethoxyphenyl)amino]pyrazine-2-carboxamide, DIMETHYL SULFOXIDE, ...
Authors:Tsuji, E.
Deposit date:2009-12-28
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3AC5
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BU of 3ac5 by Molmil
Crystal structure of triazolo pyrimidine derivative bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
Descriptor: 5-{[(1R,2S)-2-aminocyclohexyl]amino}-7-[(3,5-dimethoxyphenyl)amino]-2-(3-hydroxyphenyl)[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide, DIMETHYL SULFOXIDE, Proto-oncogene tyrosine-protein kinase LCK, ...
Authors:Tsuji, E.
Deposit date:2009-12-28
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ab initio molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3AC2
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BU of 3ac2 by Molmil
Crystal structure of pyrazolo pyrimidine derivative bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(2-amino-2-methylpropyl)amino]-2-[(3,5-dimethoxyphenyl)amino]-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide, DIMETHYL SULFOXIDE, ...
Authors:Tsuji, E.
Deposit date:2009-12-28
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
3AC8
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BU of 3ac8 by Molmil
Crystal structure of pyrazolo pyrimidine derivative bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
Descriptor: 7-[(2-amino-2-methylpropyl)amino]-5-cyclopropyl-2-[(3,5-dimethoxyphenyl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION
Authors:Tsuji, E.
Deposit date:2009-12-29
Release date:2010-06-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase
To be Published
2ZTH
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BU of 2zth by Molmil
Crystal structure of holo form of rat catechol-o-methyltransferase
Descriptor: Catechol O-methyltransferase, MAGNESIUM ION, S-ADENOSYLMETHIONINE
Authors:Tsuji, E.
Deposit date:2008-10-01
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase
J.Struct.Biol., 165, 2009

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PDB entries from 2024-08-21

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