2ZTH
Crystal structure of holo form of rat catechol-o-methyltransferase
Summary for 2ZTH
Entry DOI | 10.2210/pdb2zth/pdb |
Related | 1vid |
Descriptor | Catechol O-methyltransferase, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... (4 entities in total) |
Functional Keywords | s-adenosylmethionine dependent methyltransferase, alternative initiation, catecholamine metabolism, cell membrane, cytoplasm, magnesium, membrane, metal-binding, methyltransferase, neurotransmitter degradation, phosphoprotein, s-adenosyl-l-methionine, signal-anchor, transferase, transmembrane |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 25339.27 |
Authors | Tsuji, E. (deposition date: 2008-10-01, release date: 2009-01-13, Last modification date: 2023-11-01) |
Primary citation | Tsuji, E.,Okazaki, K.,Isaji, M.,Takeda, K. Crystal structures of the Apo and Holo form of rat catechol-O-methyltransferase J.Struct.Biol., 165:133-139, 2009 Cited by PubMed: 19111934DOI: 10.1016/j.jsb.2008.11.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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