4NQT
anti-parallel Fc-hole(T366S/L368A/Y407V) homodimer
Summary for 4NQT
Entry DOI | 10.2210/pdb4nqt/pdb |
Related | 4NQS 4NQU |
Descriptor | Ig gamma-1 chain C region (2 entities in total) |
Functional Keywords | immunoglobulin, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P01857 |
Total number of polymer chains | 1 |
Total formula weight | 24000.15 |
Authors | Eigenbrot, C.,Ultsch, M. (deposition date: 2013-11-25, release date: 2014-03-12, Last modification date: 2023-09-20) |
Primary citation | Elliott, J.M.,Ultsch, M.,Lee, J.,Tong, R.,Takeda, K.,Spiess, C.,Eigenbrot, C.,Scheer, J.M. Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction. J.Mol.Biol., 426:1947-1957, 2014 Cited by PubMed: 24576605DOI: 10.1016/j.jmb.2014.02.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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