4NQS

Knob-into-hole IgG Fc

Summary for 4NQS

• Entry DOI: 10.2210/pdb4nqs/pdb
• Related: 4NQT 4NQU
• Descriptor: Ig gamma-1 chain C region, miniZ, ... (4 entities in total)
• Functional Keywords: immunoglobulin, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01857 P01857
• Total number of polymer chains: 8
• Total formula weight: 113173.82

Authors

Eigenbrot, C.,Ultsch, M. (deposition date: 2013-11-25, release date: 2014-03-12, Last modification date: 2023-09-20)

• Primary citation: Elliott, J.M.,Ultsch, M.,Lee, J.,Tong, R.,Takeda, K.,Spiess, C.,Eigenbrot, C.,Scheer, J.M.; Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction.; J.Mol.Biol., 426:1947-1957, 2014; PubMed: 24576605; DOI: 10.1016/j.jmb.2014.02.015

Experimental method

X-RAY DIFFRACTION (2.64 Å)