8HR8
| Structure of heptameric RdrA ring | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HR9
| Structure of tetradecameric RdrA ring | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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8HRA
| Structure of heptameric RdrA ring in RNA-loading state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Archaeal ATPase, RNA (5'-R(P*GP*UP*CP*CP*AP*GP*CP*GP*UP*CP*AP*UP*CP*GP*CP*UP*GP*GP*AP*C)-3') | Authors: | Gao, Y. | Deposit date: | 2022-12-15 | Release date: | 2023-02-01 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Molecular basis of RADAR anti-phage supramolecular assemblies. Cell, 186, 2023
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5VZT
| Crystal structure of the Skp1-FBXO31 complex | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ... | Authors: | Li, Y, Jin, K, Hao, B. | Deposit date: | 2017-05-29 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5VZU
| Crystal structure of the Skp1-FBXO31-cyclin D1 complex | Descriptor: | Cyclin D1, F-box only protein 31, PHOSPHATE ION, ... | Authors: | Li, Y, Jin, K, Hao, B. | Deposit date: | 2017-05-29 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3PPV
| Crystal structure of an engineered VWF A2 domain (N1493C and C1670S) | Descriptor: | CALCIUM ION, SULFATE ION, von Willebrand factor | Authors: | Zhou, M, Dong, X, Zhong, C, Ding, J. | Deposit date: | 2010-11-25 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13 Blood, 117, 2011
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3PPX
| Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S) | Descriptor: | SODIUM ION, von Willebrand factor | Authors: | Zhou, M, Dong, X, Zhong, C, Ding, J. | Deposit date: | 2010-11-25 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13 Blood, 117, 2011
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3PPW
| Crystal structure of the D1596A mutant of an engineered VWF A2 domain (N1493C and C1670S) | Descriptor: | SODIUM ION, von Willebrand factor | Authors: | Zhou, M, Dong, X, Zhong, C, Ding, J. | Deposit date: | 2010-11-25 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13 Blood, 117, 2011
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3PPY
| Crystal structure of the D1596A/N1602A double mutant of an engineered VWF A2 domain (N1493C and C1670S) | Descriptor: | SODIUM ION, von Willebrand factor | Authors: | Zhou, M, Dong, X, Zhong, C, Ding, J. | Deposit date: | 2010-11-25 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13 Blood, 117, 2011
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7VS4
| Crystal structure of PacII_M1M2S-DNA(m6A)-SAH complex | Descriptor: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | Authors: | Zhu, J, Gao, P. | Deposit date: | 2021-10-25 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems. Nat Commun, 13, 2022
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7VRU
| Crystal structure of PacII_M1M2S-DNA-SAH complex | Descriptor: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | Authors: | Zhu, J, Gao, P. | Deposit date: | 2021-10-25 | Release date: | 2022-11-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems. Nat Commun, 13, 2022
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7DMC
| Dipyridamole binds to the N-terminal domain of human Hsp90A | Descriptor: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, CHLORIDE ION, Heat shock protein HSP 90-alpha, ... | Authors: | Shi, L, Zhou, C, Zhong, Y, Gao, J, Zhou, H, Zhang, N. | Deposit date: | 2020-12-03 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines. Biochem Pharmacol, 207, 2022
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7DWA
| Structure of a novel beta-mannanase BaMan113A with mannotriose, N236Y mutation | Descriptor: | Endo-beta-1,4-mannanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose | Authors: | Liu, W.T, Liu, W.D, Zheng, Y.Y. | Deposit date: | 2021-01-15 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Functional and structural investigation of a novel beta-mannanase BaMan113A from Bacillus sp. N16-5. Int.J.Biol.Macromol., 182, 2021
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7DW8
| Structure of a novel beta-mannanase BaMan113A with mannobiose, N236Y mutation. | Descriptor: | Endo-beta-1,4-mannanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose | Authors: | Liu, W.T, Liu, W.D, Zheng, Y.Y. | Deposit date: | 2021-01-15 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Functional and structural investigation of a novel beta-mannanase BaMan113A from Bacillus sp. N16-5. Int.J.Biol.Macromol., 182, 2021
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7DVJ
| Structure of beta-mannanase BaMan113A with mannobiose | Descriptor: | Endo-beta-1,4-mannanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose | Authors: | Liu, W.T, Liu, W.D, Zheng, Y.Y. | Deposit date: | 2021-01-13 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Functional and structural investigation of a novel beta-mannanase BaMan113A from Bacillus sp. N16-5. Int.J.Biol.Macromol., 182, 2021
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7DVZ
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7DV7
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5TPA
| Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500) | Descriptor: | (1R,2R)-2-(2-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile, GLUTAMIC ACID, GLYCINE, ... | Authors: | Wallweber, H.J.A, Lupardus, P.J. | Deposit date: | 2016-10-20 | Release date: | 2016-11-30 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
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5TP9
| Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178) | Descriptor: | 7-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-N-ethyl-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, ACETATE ION, CALCIUM ION, ... | Authors: | Wallweber, H.J.A, Lupardus, P.J. | Deposit date: | 2016-10-20 | Release date: | 2016-11-30 | Last modified: | 2017-02-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett, 8, 2017
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3TG5
| Structure of SMYD2 in complex with p53 and SAH | Descriptor: | Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ... | Authors: | Zhao, K, Wang, L. | Deposit date: | 2011-08-17 | Release date: | 2011-08-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation J.Biol.Chem., 2011
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3TG4
| Structure of SMYD2 in complex with SAM | Descriptor: | GLYCEROL, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | Authors: | Zhao, K, Wang, L. | Deposit date: | 2011-08-17 | Release date: | 2011-08-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation J.Biol.Chem., 2011
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6J9A
| Crystal structure of Arabidopsis thaliana VAL1 in complex with FLC DNA fragment | Descriptor: | B3 domain-containing transcription repressor VAL1, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3') | Authors: | Hu, H, Du, J. | Deposit date: | 2019-01-22 | Release date: | 2019-05-29 | Method: | X-RAY DIFFRACTION (2.915 Å) | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. Nat.Plants, 5, 2019
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6J9C
| Crystal structure of Arabidopsis thaliana transcription factor LEC2-DNA complex | Descriptor: | B3 domain-containing transcription factor LEC2, DNA (5'-D(*CP*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*T)-3') | Authors: | Hu, H, Du, J. | Deposit date: | 2019-01-22 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. Nat.Plants, 5, 2019
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6J9B
| Arabidopsis FUS3-DNA complex | Descriptor: | B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3') | Authors: | Hu, H, Du, J. | Deposit date: | 2019-01-22 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. Nat.Plants, 5, 2019
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2UXN
| Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | Descriptor: | CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H. | Deposit date: | 2007-03-28 | Release date: | 2007-05-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation. Nat.Struct.Mol.Biol., 14, 2007
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