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7NT7
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BU of 7nt7 by Molmil
Solution structure of toll like receptor 1 (TLR1) TIR domain
Descriptor: Toll-like receptor 1
Authors:Mineev, K.S, Lushpa, V.A, Goncharuk, M.V.
Deposit date:2021-03-09
Release date:2021-08-25
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7NUW
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BU of 7nuw by Molmil
Crystal structure of the TIR domain of human TLR1 (crystallised with Zn2+ ions)
Descriptor: Toll-like receptor 1
Authors:Vakhrameev, D.D, Luginina, A.P, Shevtsov, M.B, Lushpa, V.A, Mineev, K.S, Borshchevskiy, V.I.
Deposit date:2021-03-15
Release date:2021-08-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn 2+ ions.
Commun Biol, 4, 2021
7O9U
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BU of 7o9u by Molmil
Solution structure of oxidized cytochrome c552 from Thioalkalivibrio paradoxus
Descriptor: Cytochrome c552, HEME C
Authors:Britikov, V.V, Britikova, E.V, Altukhov, D.A, Timofeev, V.I, Dergousova, N.I, Rakitina, T.V, Tikhonova, T.V, Usanov, S.A, Popov, V.O, Bocharov, E.V.
Deposit date:2021-04-17
Release date:2021-05-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Unusual Cytochrome c 552 from Thioalkalivibrio paradoxus : Solution NMR Structure and Interaction with Thiocyanate Dehydrogenase.
Int J Mol Sci, 23, 2022
5LV6
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BU of 5lv6 by Molmil
N-terminal motif dimerization of EGFR transmembrane domain in bicellar environment
Descriptor: Epidermal growth factor receptor
Authors:Bragin, P, Bocharov, E, Mineev, K, Bocharova, O, Arseniev, A.
Deposit date:2016-09-12
Release date:2017-04-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment.
Biochemistry, 56, 2017
6F61
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BU of 6f61 by Molmil
NMR structure of purotoxin-6
Descriptor: purotoxin-6
Authors:Nadezhdin, K.D, Oparin, P.B, Vassilevski, A.A, Arseniev, A.S, Grishin, E.V.
Deposit date:2017-12-04
Release date:2018-12-19
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:NMR structure of purotoxin-6
To Be Published
8BVC
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BU of 8bvc by Molmil
Solution structure of Metridium senile toxin Ms13-1 with the unique fold
Descriptor: Ms13-1
Authors:Mineev, K.S, Arseniev, A.S, Andreev, Y.A, Osmakov, D.I, Khasanov, T.A.
Deposit date:2022-12-06
Release date:2023-12-20
Method:SOLUTION NMR
Cite:Solution structure of Metridium senile toxin Ms13-1 with the unique fold
To Be Published
5T8A
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BU of 5t8a by Molmil
Recombinant cytotoxin-I from the venom of cobra N. oxiana
Descriptor: Cytotoxin 1
Authors:Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G.
Deposit date:2016-09-07
Release date:2017-09-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
7AY8
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BU of 7ay8 by Molmil
NMR solution structure of Tbo-IT2
Descriptor: Tbo-IT2
Authors:Mineev, K.S, Kornilov, F.D, Lushpa, V.A, Korolkova, Y.A, Maleeva, E.E, Andreev, Y.A, Kozlov, S.A, Arseniev, A.S.
Deposit date:2020-11-11
Release date:2021-03-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:New Insectotoxin from Tibellus Oblongus Spider Venom Presents Novel Adaptation of ICK Fold.
Toxins, 13, 2021
2LOH
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BU of 2loh by Molmil
Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment
Descriptor: P3(42)
Authors:Nadezhdin, K, Bocharov, E, Bocharova, O, Arseniev, A.
Deposit date:2012-01-24
Release date:2012-05-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment.
Febs Lett., 586, 2012
2MJO
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BU of 2mjo by Molmil
NMR structure of p75 transmembrane domain C257A mutant in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2014-01-15
Release date:2015-01-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2LZO
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BU of 2lzo by Molmil
Spatial structure of Pi-AnmTX Ugr 9a-1
Descriptor: UGTX
Authors:Mineev, K, Arseniev, A.
Deposit date:2012-10-08
Release date:2013-07-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Sea Anemone Peptide with Uncommon beta-Hairpin Structure Inhibits Acid-sensing Ion Channel 3 (ASIC3) and Reveals Analgesic Activity.
J.Biol.Chem., 288, 2013
2MET
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BU of 2met by Molmil
NMR spatial structure of the trimeric mutant TM domain of VEGFR2 receptor.
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.A, Shulepko, M, Lyukmanova, E.N, Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
2N2A
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BU of 2n2a by Molmil
Spatial structure of HER2/ErbB2 dimeric transmembrane domain in the presence of cytoplasmic juxtamembrane domains
Descriptor: Receptor tyrosine-protein kinase erbB-2
Authors:Bragin, P.E, Mineev, K.S, Bocharov, E, Bocharova, O, Arseniev, A.
Deposit date:2015-05-05
Release date:2016-02-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:HER2 Transmembrane Domain Dimerization Coupled with Self-Association of Membrane-Embedded Cytoplasmic Juxtamembrane Regions.
J.Mol.Biol., 428, 2016
2N5S
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BU of 2n5s by Molmil
Spatial structure of EGFR transmembrane and juxtamembrane domains in DPC micelles
Descriptor: Epidermal growth factor receptor
Authors:Mineev, K, Bocharov, E, Bocharova, O, Arseniev, A.
Deposit date:2015-07-27
Release date:2015-10-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Membrane Mimetic Affects the Spatial Structure and Mobility of EGFR Transmembrane and Juxtamembrane Domains.
Biochemistry, 54, 2015
2MZF
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BU of 2mzf by Molmil
Purotoxin-2 NMR structure in water
Descriptor: Purotoxin-2
Authors:Nadezhdin, K, Vassilevski, A, Oparin, P, Grishin, E, Arseniev, A.
Deposit date:2015-02-12
Release date:2016-04-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of purotoxin-2 from wolf spider: modular design and membrane-assisted mode of action in arachnid toxins.
Biochem. J., 473, 2016
5NAO
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BU of 5nao by Molmil
NMR structure of TLR4 transmembrane domain (624-657) in DPC micelles
Descriptor: Toll-like receptor 4
Authors:Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S.
Deposit date:2017-02-28
Release date:2018-03-21
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
5NAM
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BU of 5nam by Molmil
NMR structure of TLR4 transmembrane domain (624-670) in DMPG/DHPC bicelles
Descriptor: Toll-like receptor 4
Authors:Mineev, K.S, Goncharuk, S.A, Goncharuk, M.V, Arseniev, A.S.
Deposit date:2017-02-28
Release date:2017-09-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
2N85
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BU of 2n85 by Molmil
NMR structure of OtTx1a - AMP in DPC micelles
Descriptor: Spiderine-1a
Authors:Nadezhdin, K, Romanovskaya, D, Sachkova, M, Vassilevski, A, Grishin, E, Kovalchuk, S, Arseniev, A.
Deposit date:2015-10-05
Release date:2016-10-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment.
Protein Sci., 26, 2017
2N86
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BU of 2n86 by Molmil
NMR structure of OtTx1a - ICK
Descriptor: Spiderine-1a
Authors:Nadezhdin, K, Romanovskaya, D, Sachkova, M, Vassilevski, A, Grishin, E, Kovalchuk, S, Arseniev, A.
Deposit date:2015-10-05
Release date:2016-10-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment.
Protein Sci., 26, 2017
2N90
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BU of 2n90 by Molmil
TrkA transmembrane domain NMR structure in DPC micelles
Descriptor: High affinity nerve growth factor receptor
Authors:Nadezhdin, K, Goncharuk, S, Arseniev, A.
Deposit date:2015-10-29
Release date:2016-11-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.
J.Biol.Chem., 295, 2020
2MIC
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BU of 2mic by Molmil
NMR structure of p75 transmembrane domain in DPC micelles
Descriptor: Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
Deposit date:2013-12-12
Release date:2014-12-24
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MZG
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BU of 2mzg by Molmil
Purotoxin-2 NMR structure in DPC micelles
Descriptor: Purotoxin-2
Authors:Nadezhdin, K, Oparin, P, Vassilevski, A, Grishin, E, Arseniev, A.
Deposit date:2015-02-12
Release date:2016-04-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of purotoxin-2 from wolf spider: modular design and membrane-assisted mode of action in arachnid toxins.
Biochem. J., 473, 2016
2MQU
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BU of 2mqu by Molmil
Spatial structure of Hm-3, a membrane-active spider toxin affecting sodium channels
Descriptor: Neurotoxin Hm-3
Authors:Myshkin, M.Y, Shenkarev, Z.O, Paramonov, A.S, Berkut, A.A, Grishin, E.V, Vassilevski, A.A.
Deposit date:2014-06-27
Release date:2014-11-05
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
J. Biol. Chem., 290, 2015
2M1F
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BU of 2m1f by Molmil
NMR Structure of Antiamoebin I (peptaibol antibiotic) bound to DMPC/DHPC bicelles
Descriptor: Antiamoebin I
Authors:Shenkarev, Z.O, Paramonov, A.S, Gizatullina, A.K.
Deposit date:2012-11-27
Release date:2012-12-12
Last modified:2013-10-02
Method:SOLUTION NMR
Cite:Peptaibol antiamoebin I: spatial structure, backbone dynamics, interaction with bicelles and lipid-protein nanodiscs, and pore formation in context of barrel-stave model.
Chem.Biodivers., 10, 2013
6RC7
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BU of 6rc7 by Molmil
NMR structure of cytotoxin 3 from Naja kaouthia in solution, major form
Descriptor: Cytotoxin 3
Authors:Dubinnyi, M.A, Dubovskii, P.V, Utkin, Y.N, Arseniev, A.S.
Deposit date:2019-04-11
Release date:2020-05-13
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:The omega-loop of cobra cytotoxins tolerates multiple amino acid substitutions.
Biochem.Biophys.Res.Commun., 558, 2021

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