2N90
TrkA transmembrane domain NMR structure in DPC micelles
Summary for 2N90
| Entry DOI | 10.2210/pdb2n90/pdb |
| NMR Information | BMRB: 25872 |
| Descriptor | High affinity nerve growth factor receptor (1 entity in total) |
| Functional Keywords | neurotrophin receptor, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 8428.18 |
| Authors | Nadezhdin, K.,Goncharuk, S.,Arseniev, A. (deposition date: 2015-10-29, release date: 2016-11-09, Last modification date: 2023-06-14) |
| Primary citation | Franco, M.L.,Nadezhdin, K.D.,Goncharuk, S.A.,Mineev, K.S.,Arseniev, A.S.,Vilar, M. Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor. J.Biol.Chem., 295:275-286, 2020 Cited by PubMed: 31801826DOI: 10.1074/jbc.RA119.011312 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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