5L0L
 
 | | Crystal structure of Uncharacterized protein LPG0439 | | Descriptor: | CHLORIDE ION, SULFATE ION, Uncharacterized protein | | Authors: | Chang, C, Skarina, T, Khutoreskaya, G, Savchenko, A, Joachimiak, A. | | Deposit date: | 2016-07-27 | | Release date: | 2016-08-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of Uncharacterized protein LPG0439
To Be Published
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6U69
 | | Crystal structure of Yck2 from Candida albicans, apoenzyme | | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-08-29 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2.
Cell Chem Biol, 27, 2020
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6U6A
 | | Crystal structure of Yck2 from Candida albicans in complex with kinase inhibitor GW461484A | | Descriptor: | 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine, SULFATE ION, Serine/threonine protein kinase | | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Chang, C, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-08-29 | | Release date: | 2019-10-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2.
Cell Chem Biol, 27, 2020
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6BAL
 | | 2.1 Angstrom Resolution Crystal Structure of Malate Dehydrogenase from Haemophilus influenzae in Complex with L-Malate | | Descriptor: | (2S)-2-hydroxybutanedioic acid, CHLORIDE ION, Malate dehydrogenase | | Authors: | Minasov, G, Wawrzak, Z, Skarina, T, Grimshaw, S, Satchell, K.J.F, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-10-13 | | Release date: | 2017-10-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 2.1 Angstrom Resolution Crystal Structure of Malate Dehydrogenase from Haemophilus influenzae in Complex with L-Malate
To Be Published
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1ILV
 | | Crystal Structure Analysis of the TM107 | | Descriptor: | STATIONARY-PHASE SURVIVAL PROTEIN SURE HOMOLOG | | Authors: | Zhang, R, Joachimiak, A, Edwards, A, Savchenko, A, Beasley, S, Evdokimova, E, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-05-08 | | Release date: | 2001-10-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase.
Structure, 9, 2001
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7K3N
 | | Crystal Structure of NSP1 from SARS-CoV-2 | | Descriptor: | Host translation inhibitor nsp1 | | Authors: | Semper, C, Watanabe, N, Chang, C, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2020-09-11 | | Release date: | 2020-09-30 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural characterization of nonstructural protein 1 from SARS-CoV-2.
Iscience, 24, 2021
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6B8W
 | | 1.9 Angstrom Resolution Crystal Structure of Cupin_2 Domain (pfam 07883) of XRE Family Transcriptional Regulator from Enterobacter cloacae. | | Descriptor: | MANGANESE (II) ION, THIOCYANATE ION, XRE family transcriptional regulator | | Authors: | Minasov, G, Wawrzak, Z, Skarina, T, McChesney, C, Grimshaw, S, Sandoval, J, Satchell, K.J.F, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-10-09 | | Release date: | 2017-10-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | 1.9 Angstrom Resolution Crystal Structure of Cupin_2 Domain (pfam 07883) of XRE Family Transcriptional Regulator from Enterobacter cloacae.
To Be Published
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4WRP
 | | The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 | | Descriptor: | Uncharacterized protein | | Authors: | Cuff, M.E, Evdokimova, E, Egorova, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-10-24 | | Release date: | 2015-03-18 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The C-terminal domain of gene product lpg0944 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1.
To Be Published
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6OZ7
 | | Putative oxidoreductase from Escherichia coli str. K-12 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, TRIETHYLENE GLYCOL, ... | | Authors: | Osipiuk, J, Skarina, T, Mesa, N, Endres, M, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-05-15 | | Release date: | 2019-05-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Putative oxidoreductase from Escherichia coli str. K-12
to be published
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1INL
 | | Crystal Structure of Spermidine Synthase from Thermotoga Maritima | | Descriptor: | Spermidine synthase | | Authors: | Korolev, S, Skarina, T, Ikeguchi, Y, Pegg, A.E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-05-14 | | Release date: | 2001-11-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Nat.Struct.Biol., 9, 2002
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6U8J
 | | Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from Candida auris | | Descriptor: | Phospho-2-dehydro-3-deoxyheptonate aldolase, UNKNOWN ATOM OR ION | | Authors: | Michalska, K, Evdokimova, E, Semper, C, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-09-05 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.492 Å) | | Cite: | Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from
Candida auris
To Be Published
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6U83
 | | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-ALANINE, Outer membrane associated protein, ... | | Authors: | Michalska, K, Skarina, T, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-09-04 | | Release date: | 2019-09-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3566 Å) | | Cite: | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
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1H2H
 | | Crystal structure of TM1643 | | Descriptor: | HYPOTHETICAL PROTEIN TM1643, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Yang, Z, Savchenko, A, Edwards, A, Arrowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2002-08-08 | | Release date: | 2002-08-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
J. Biol. Chem., 278, 2003
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5HT0
 | | Crystal structure of an Antibiotic_NAT family aminoglycoside acetyltransferase HMB0038 from an uncultured soil metagenomic sample in complex with coenzyme A | | Descriptor: | Aminoglycoside acetyltransferase HMB0005, COENZYME A, SULFATE ION | | Authors: | Xu, Z, Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-01-26 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.752 Å) | | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
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6UX3
 | | Crystal structure of acetoin dehydrogenase from Enterobacter cloacae | | Descriptor: | Acetoin dehydrogenase, DI(HYDROXYETHYL)ETHER, GLYCEROL | | Authors: | Chang, C, Skarina, T, Mesa, N, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-11-06 | | Release date: | 2019-11-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.198 Å) | | Cite: | Crystal structure of acetoin dehydrogenase from Enterobacter cloacae
To Be Published
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6UVZ
 | | Amidohydrolase 2 from Bifidobacterium longum subsp. infantis | | Descriptor: | Amidohydrolase 2, CITRIC ACID, NONAETHYLENE GLYCOL | | Authors: | Chang, C, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2019-11-04 | | Release date: | 2020-02-26 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.898 Å) | | Cite: | Amidohydrolase 2 from Bifidobacterium longum subsp. infantis
To Be Published
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5F13
 | | Structure of Mn bound DUF89 from Saccharomyces cerevisiae | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Nocek, B, Skarina, T, Joachimiak, A, Savchenko, A, Yakunin, A. | | Deposit date: | 2015-11-30 | | Release date: | 2016-03-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.393 Å) | | Cite: | A family of metal-dependent phosphatases implicated in metabolite damage-control.
Nat.Chem.Biol., 12, 2016
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3LQY
 | | Crystal structure of putative isochorismatase hydrolase from Oleispira antarctica | | Descriptor: | GLYCEROL, putative isochorismatase hydrolase | | Authors: | Goral, A, Chruszcz, M, Kagan, O, Cymborowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2010-02-10 | | Release date: | 2010-03-16 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica.
J.Struct.Funct.Genom., 13, 2012
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6UXT
 | | Crystal structure of unknown function protein yfdX from Shigella flexneri | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... | | Authors: | Chang, C, Skarina, T, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-11-08 | | Release date: | 2019-11-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.797 Å) | | Cite: | Crystal structure of unknown function protein yfdX from Shigella flexneri
To Be Published
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5IQJ
 | | 1.9 Angstrom Crystal Structure of Protein with Unknown Function from Vibrio cholerae. | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | Authors: | Minasov, G, Wawrzak, Z, Stogios, P.J, Skarina, T, Seed, K.D, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-03-10 | | Release date: | 2016-03-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | 1.9 Angstrom Crystal Structure of Protein with Unknown Function from Vibrio cholerae.
To Be Published
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6OSX
 | | Crystal structure of uncharacterized protein ECL_02694 | | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, Protein YmbA, ... | | Authors: | Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-05-02 | | Release date: | 2019-05-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of uncharacterized protein ECL_02694
To Be Published
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6OTV
 | | Crystal structure of putative isomerase EC2056 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... | | Authors: | Chang, C, Evdokimova, E, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2019-05-03 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of putative isomerase EC2056
To Be Published
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5JD8
 | | Crystal structure of the serine endoprotease from Yersinia pestis | | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DI(HYDROXYETHYL)ETHER, Periplasmic serine peptidase DegS, ... | | Authors: | Filippova, E.V, Wawrzsak, Z, Sandoval, J, Skarina, T, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-04-15 | | Release date: | 2016-05-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of the serine endoprotease from Yersinia pestis
To Be Published
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1JQ3
 | | Crystal Structure of Spermidine Synthase in Complex with Transition State Analogue AdoDATO | | Descriptor: | S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, Spermidine synthase | | Authors: | Korolev, S, Ikeguchi, Y, Skarina, T, Beasley, S, Edwards, A, Joachimiak, A, Pegg, A.E, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-08-03 | | Release date: | 2001-11-21 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Nat.Struct.Biol., 9, 2002
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6B3N
 | | Solution structure of the N-terminal domain of the effector NleG5-1 from Escherichia coli O157:H7 str. Sakai | | Descriptor: | NleG5-1 | | Authors: | Valleau, D, Houliston, S, Lemak, A, Anderson, W.F, Arrowsmith, C, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-09-22 | | Release date: | 2017-11-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the N-terminal domain of the effector NleG5-1 from Escherichia coli O157:H7 str. Sakai
To Be Published
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