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1PAQ
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BU of 1paq by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF EUKARYOTIC INITIATION FACTOR 2B EPSILON
Descriptor: Translation initiation factor eIF-2B epsilon subunit
Authors:Boesen, T, Andersen, G.R, Pavitt, G.D.
Deposit date:2003-05-14
Release date:2004-02-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue.
J.Biol.Chem., 279, 2004
3CU7
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BU of 3cu7 by Molmil
Human Complement Component 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
Authors:Fredslund, F, Andersen, G.R.
Deposit date:2008-04-16
Release date:2008-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
1PBU
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BU of 1pbu by Molmil
Solution structure of the C-terminal domain of the human eEF1Bgamma subunit
Descriptor: Elongation factor 1-gamma
Authors:Vanwetswinkel, S, Kriek, J, Andersen, G.R, Guntert, P, Dijk, J, Canters, G.W, Siegal, G.
Deposit date:2003-05-15
Release date:2003-07-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:1H, (15)N and (13)C resonance assignments of the highly conserved 19 kDa C-terminal domain from human Elongation Factor 1Bgamma.
J.Biomol.Nmr, 26, 2003
7ASG
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BU of 7asg by Molmil
TGFBIp mutant R555W
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Nielsen, N.S, Gadeberg, T.A.F, Andersen, G.R.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
5HLO
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BU of 5hlo by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group C2221
Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
5HLV
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BU of 5hlv by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group P212121
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
5I5K
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BU of 5i5k by Molmil
Structure of complement C5 in complex with eculizumab
Descriptor: Complement C5, Eculizumab heavy chain (variable domain), Eculizumab light chain (variable domain), ...
Authors:Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2016-02-15
Release date:2016-03-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway.
J Immunol., 197, 2016
5I8Q
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BU of 5i8q by Molmil
S. cerevisiae Prp43 in complex with RNA and ADPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ...
Authors:He, Y, Nielsen, K.H, Andersen, G.R.
Deposit date:2016-02-19
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
RNA, 23, 2017
4LP5
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BU of 4lp5 by Molmil
Crystal structure of the full-length human RAGE extracellular domain (VC1C2 fragment)
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4M76
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BU of 4m76 by Molmil
Integrin I domain of complement receptor 3 in complex with C3d
Descriptor: Complement C3, Integrin alpha-M, NICKEL (II) ION
Authors:Bajic, G, Yatime, L, Vorup-Jensen, T, Andersen, G.R.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LP4
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BU of 4lp4 by Molmil
Crystal structure of the human RAGE VC1 fragment in space group P62
Descriptor: Advanced glycosylation end product-specific receptor, SODIUM ION
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4OF5
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BU of 4of5 by Molmil
Refinement of RAGE-DNA complex in 3S59 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-14
Release date:2014-04-23
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
4P3A
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BU of 4p3a by Molmil
Crystal structure of the mouse C5a anaphylatoxin
Descriptor: Complement C5, FORMIC ACID
Authors:Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4OFV
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BU of 4ofv by Molmil
Refinement of RAGE-DNA complex in 3S58 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-15
Release date:2014-04-23
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
4P3B
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BU of 4p3b by Molmil
Crystal structure of the mouse C5a-desArg anaphylatoxin
Descriptor: Complement C5, FORMIC ACID
Authors:Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4P39
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BU of 4p39 by Molmil
Crystal structure of the human C5aR antagonist C5a-A8
Descriptor: Complement C5
Authors:Yatime, L, Schatz-Jakobsen, J.A, Larsen, C, Andersen, G.R.
Deposit date:2014-03-06
Release date:2014-06-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural and functional characterization of human and murine C5a anaphylatoxins.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
8RD2
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BU of 8rd2 by Molmil
Trypanosoma brucei Invariant Surface Glycoprotein 75 (ISG75)
Descriptor: Invariant surface glycoprotein
Authors:Stodkilde-Jorgensen, K, Mikkelsen, J.H.
Deposit date:2023-12-07
Release date:2024-02-14
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis.
J Immunol., 212, 2024
6TAV
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BU of 6tav by Molmil
Crystal structure of endopeptidase-induced alpha2-macroglobulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
Authors:Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J.
Deposit date:2019-10-30
Release date:2021-05-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin
Proc.Natl.Acad.Sci.USA, 2022
7B28
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BU of 7b28 by Molmil
Complement inhibitor CirpA3 from Rhipicephalus pulchellus
Descriptor: CirpA3, SULFATE ION
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B29
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BU of 7b29 by Molmil
Complement inhibitor CirpA4 from Rhipicephalus appendiculatus
Descriptor: CADMIUM ION, CHLORIDE ION, CirpA4
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2A
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BU of 7b2a by Molmil
Complement inhibitor CirpA5 from Rhipicephalus appendiculatus
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CirpA5
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B2D
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BU of 7b2d by Molmil
Complement inhibitor CirpA1 from Rhipicephalus pulchellus
Descriptor: CirpA1, D-MALATE
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
7B26
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BU of 7b26 by Molmil
CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3
Descriptor: CirpA1, Properdin, alpha-D-mannopyranose, ...
Authors:Lea, S.M, Johnson, S, Braunger, K.
Deposit date:2020-11-26
Release date:2021-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nat Commun, 13, 2022
8PIH
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BU of 8pih by Molmil
Structure of Api m1 in complex with two nanobodies
Descriptor: CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ...
Authors:Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R.
Deposit date:2023-06-21
Release date:2024-05-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1
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