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1G7J
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BU of 1g7j by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7M
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BU of 1g7m by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7L
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BU of 1g7l by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7I
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BU of 1g7i by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1BEC
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BU of 1bec by Molmil
BETA CHAIN OF A T CELL ANTIGEN RECEPTOR
Descriptor: 14.3.D T CELL ANTIGEN RECEPTOR
Authors:Bentley, G.A, Boulot, G, Karjalainen, K, Mariuzza, R.A.
Deposit date:1995-02-28
Release date:1995-10-25
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the beta chain of a T cell antigen receptor.
Science, 267, 1995
1SBB
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BU of 1sbb by Molmil
T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB
Descriptor: PROTEIN (14.3.D T CELL ANTIGEN RECEPTOR), PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN B)
Authors:Li, H, Mariuzza, R.A.
Deposit date:1999-02-22
Release date:1999-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B.
Immunity, 9, 1998
1NKO
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BU of 1nko by Molmil
Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7
Descriptor: Sialic acid binding Ig-like lectin 7
Authors:Dimasi, N, Attril, H, van Aalten, D.M.F, Moretta, L, Biassoni, R, Mariuzza, R.A.
Deposit date:2003-01-03
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta Crystallogr.,Sect.D, 60, 2004
1P4L
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BU of 1p4l by Molmil
Crystal structure of NK receptor Ly49C mutant with its MHC class I ligand H-2Kb
Descriptor: Beta-2-microglobulin, LY49-C, MHC CLASS I H-2KB HEAVY CHAIN, ...
Authors:Dam, J, Guan, R, Natarajan, K, Dimasi, N, Mariuzza, R.A.
Deposit date:2003-04-23
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
1R1Q
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BU of 1r1q by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY191 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
6VQO
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BU of 6vqo by Molmil
T cell receptor-p53-HLA-A2 complex
Descriptor: Beta-2-microglobulin, MHC class I antigen, T-cell receptor 1a2, ...
Authors:Wu, D, Gallagher, D.T, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-05
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VR1
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BU of 6vr1 by Molmil
Complex of HLA-A2, a class I MHC, with a p53 peptide
Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen
Authors:Wu, D, Pierce, B.G, Gallagher, D.T, Mariuzza, R.A.
Deposit date:2020-02-06
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VTH
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BU of 6vth by Molmil
p53-specific T cell receptor
Descriptor: SULFATE ION, T-cell Receptor 12-6, Alfa chain, ...
Authors:Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
1TWQ
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BU of 1twq by Molmil
Crystal structure of the C-terminal PGN-binding domain of human PGRP-Ialpha in complex with PGN analog muramyl tripeptide
Descriptor: N-acetyl-beta-muramic acid, NICKEL (II) ION, muramyl tripeptide, ...
Authors:Guan, R, Roychowdury, A, Boons, G.-A, Mariuzza, R.A.
Deposit date:2004-07-01
Release date:2004-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for peptidoglycan binding by peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.USA, 101, 2004
1R1P
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BU of 1r1p by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY171 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
1R1S
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BU of 1r1s by Molmil
Structural Basis for Differential Recognition of Tyrosine Phosphorylated Sites in the Linker for Activation of T cells (LAT) by the Adaptor Protein Gads
Descriptor: GRB2-related adaptor protein 2, LAT pY226 peptide, SULFATE ION
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2003-09-24
Release date:2004-09-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads.
Embo J., 23, 2004
6VRN
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BU of 6vrn by Molmil
T cell receptor-p53-HLA-A2 complex
Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ...
Authors:Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-08
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VTC
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BU of 6vtc by Molmil
p53-specific T cell receptor
Descriptor: T-cell Receptor 1a2, p53-specific T cell receptor, B-chain
Authors:Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6VRM
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BU of 6vrm by Molmil
T cell receptor-p53-HLA-A2 complex
Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ...
Authors:Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-08
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6WJU
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BU of 6wju by Molmil
Fab Fragment of Anti-human LAG3 antibody (4A10)
Descriptor: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-14
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WK4
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BU of 6wk4 by Molmil
Fab Fragment of Anti-human LAG3 antibody (13E2)
Descriptor: 13E2 Fab Heavy Chain, 13E2 Fab Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-15
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKL
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BU of 6wkl by Molmil
Fab Fragment of Anti-human LAG3 antibody (BAP050)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKM
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BU of 6wkm by Molmil
Fab Fragment of Anti-human LAG3 antibody (22D2)
Descriptor: 22D2 Fab Heavy Chain, 22D2 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 2023
6VR5
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BU of 6vr5 by Molmil
Complex of HLA-A2, a class I MHC, with a p53 peptide
Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen
Authors:Wu, D, Gallagher, D.T, Pierce, B.G, Mariuzza, R.A.
Deposit date:2020-02-06
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
6X9X
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BU of 6x9x by Molmil
Crystal structure of Fab fragment of Anti-HCV E2 antibody (HC84.26)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, HC84.26 Fab Heavy Chain, ...
Authors:Shahid, S, Mariuzza, R.A.
Deposit date:2020-06-03
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Bivalent Antibody Fab Fragment.
J.Mol.Biol., 433, 2020
1PYW
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BU of 1pyw by Molmil
Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Descriptor: 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, Enterotoxin type C-3, HLA class II histocompatibility antigen, ...
Authors:Zavala-Ruiz, Z, Sundberg, E.J, Stone, J.D, DeOliveira, D.B, Chan, I.C, Svendsen, J, Mariuzza, R.A, Stern, L.J.
Deposit date:2003-07-09
Release date:2003-12-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1
J.Biol.Chem., 278, 2003

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PDB entries from 2024-07-17

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