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2H55
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BU of 2h55 by Molmil
Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-DZ8
Descriptor: 2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein HSP 90-alpha 4
Authors:Immormino, R.M, Gewirth, D.T.
Deposit date:2006-05-25
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.
J.Med.Chem., 49, 2006
4ME2
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BU of 4me2 by Molmil
Crystal Structure of THA8 protein from Brachypodium distachyon
Descriptor: Uncharacterized protein
Authors:Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Melcher, K, Xu, H.E.
Deposit date:2013-08-24
Release date:2013-10-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
6A6G
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BU of 6a6g by Molmil
Crystal structure of thermostable FiSufS-SufU complex from thermophilic Fervidobacterium Islandicum AW-1
Descriptor: Cysteine desulfurase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H.
Deposit date:2018-06-27
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation.
Microb Biotechnol, 2020
6A6E
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BU of 6a6e by Molmil
Crystal structure of thermostable Cysteine desulfurase (FiSufS) from thermophilic Fervidobacterium Islandicum AW-1
Descriptor: CITRIC ACID, Cysteine desulfurase, DI(HYDROXYETHYL)ETHER, ...
Authors:Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H.
Deposit date:2018-06-27
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The sulfur formation system mediating extracellular cysteine-cystine recycling in Fervidobacterium islandicum AW-1 is associated with keratin degradation.
Microb Biotechnol, 2020
5YKF
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BU of 5ykf by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.33 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKG
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BU of 5ykg by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKE
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BU of 5yke by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
Authors:Chen, L, Wu, J.X.
Deposit date:2017-10-14
Release date:2018-04-18
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW9
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BU of 5yw9 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWB
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BU of 5ywb by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-30
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWC
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BU of 5ywc by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW8
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BU of 5yw8 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWD
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BU of 5ywd by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWA
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BU of 5ywa by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW7
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BU of 5yw7 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
8HBE
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BU of 8hbe by Molmil
Structure of human soluble guanylate cyclase in the inactive state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBH
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BU of 8hbh by Molmil
Structure of human soluble guanylate cyclase in the NO-activated state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
8HBF
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BU of 8hbf by Molmil
Structure of human soluble guanylate cyclase in the NO+Rio state at 3.1 angstrom
Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ...
Authors:Chen, L, Liu, R.
Deposit date:2022-10-28
Release date:2023-04-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.
Nitric Oxide, 134-135, 2023
6L48
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BU of 6l48 by Molmil
Structure of the human sterol O-acyltransferase 1 in resting state
Descriptor: CHOLESTEROL, Sterol O-acyltransferase 1
Authors:Chen, L, Guan, C, Niu, Y.
Deposit date:2019-10-16
Release date:2020-04-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor.
Nat Commun, 11, 2020
6L47
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BU of 6l47 by Molmil
Structure of the human sterol O-acyltransferase 1 in complex with CI-976
Descriptor: 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide, CHOLESTEROL, Sterol O-acyltransferase 1
Authors:Chen, L, Guan, C, Niu, Y.
Deposit date:2019-10-16
Release date:2020-04-29
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor.
Nat Commun, 11, 2020
6JQ0
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BU of 6jq0 by Molmil
CryoEM structure of Abo1 Walker B (E372Q) mutant hexamer - ATP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Uncharacterized AAA domain-containing protein C31G5.19, ...
Authors:Cho, C, Jang, J, Song, J.J.
Deposit date:2019-03-28
Release date:2019-12-25
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
6JPQ
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BU of 6jpq by Molmil
CryoEM structure of Abo1 hexamer - ADP complex
Descriptor: Uncharacterized AAA domain-containing protein C31G5.19
Authors:Cho, C, Jang, J, Song, J.J.
Deposit date:2019-03-27
Release date:2020-08-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.44 Å)
Cite:Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
6JPU
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BU of 6jpu by Molmil
CryoEM structure of Abo1 hexamer - apo complex
Descriptor: Uncharacterized AAA domain-containing protein C31G5.19
Authors:Cho, C, Jang, J, Song, J.J.
Deposit date:2019-03-28
Release date:2019-12-25
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
7E4T
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BU of 7e4t by Molmil
Human TRPC5 apo state structure at 3 angstrom
Descriptor: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ...
Authors:Chen, L, Song, K, Wei, M, Guo, W.
Deposit date:2021-02-15
Release date:2021-03-31
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Elife, 10, 2021
7DXD
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BU of 7dxd by Molmil
Structure of TRPC3 at 3.9 angstrom in 1340 nM free calcium state
Descriptor: CALCIUM ION, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ...
Authors:Chen, L, Guo, W.
Deposit date:2021-01-18
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
7DXF
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BU of 7dxf by Molmil
Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
Authors:Chen, L, Guo, W.
Deposit date:2021-01-18
Release date:2022-02-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022

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