5W96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w96 by Molmil](/molmil-images/mine/5w96) | Solution structure of phage derived peptide inhibitor of frizzled 7 receptor | Descriptor: | Fz7 binding peptide | Authors: | Nile, A.H, de Sousa e Melo, F, Mukund, S, Piskol, R, Hansen, S, Zhou, L, Zhang, Y, Fu, Y, Gogol, E.B, Komuves, L.G, Modrusan, Z, Angers, S, Franke, Y, Koth, C, Fairbrother, W.J, Wang, W, de Sauvage, F.J, Hannoush, R.N. | Deposit date: | 2017-06-22 | Release date: | 2018-04-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat. Chem. Biol., 14, 2018
|
|
4JNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jne by Molmil](/molmil-images/mine/4jne) | Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Hsp70 CHAPERONE DnaK, ... | Authors: | Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. | Deposit date: | 2013-03-15 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
|
|
4JNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jnf by Molmil](/molmil-images/mine/4jnf) | Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP | Descriptor: | Hsp70 CHAPERONE DnaK | Authors: | Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. | Deposit date: | 2013-03-15 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.621 Å) | Cite: | Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
|
|
5Y2Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y2q by Molmil](/molmil-images/mine/5y2q) | |
5Y35
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y35 by Molmil](/molmil-images/mine/5y35) | |
5Y65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y65 by Molmil](/molmil-images/mine/5y65) | |
5EAZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eaz by Molmil](/molmil-images/mine/5eaz) | crystal form I of YfiB belonging to space groups P21 | Descriptor: | SULFATE ION, YfiB | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | Deposit date: | 2015-10-17 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system Protein Cell, 7, 2016
|
|
5EB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eb0 by Molmil](/molmil-images/mine/5eb0) | crystal form II of YfiB belonging to P41 | Descriptor: | SULFATE ION, YfiB | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | Deposit date: | 2015-10-17 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system Protein Cell, 7, 2016
|
|
5E86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e86 by Molmil](/molmil-images/mine/5e86) | isolated SBD of BiP with loop34 modification | Descriptor: | 78 kDa glucose-regulated protein | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2015-12-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.681 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
|
|
5EB2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eb2 by Molmil](/molmil-images/mine/5eb2) | Trp-bound YfiR | Descriptor: | SULFATE ION, TRYPTOPHAN, YfiR | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | Deposit date: | 2015-10-17 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.709 Å) | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system Protein Cell, 7, 2016
|
|
5E84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e84 by Molmil](/molmil-images/mine/5e84) | ATP-bound state of BiP | Descriptor: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
|
|
5EB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eb1 by Molmil](/molmil-images/mine/5eb1) | the YfiB-YfiR complex | Descriptor: | SULFATE ION, YfiB, YfiR | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | Deposit date: | 2015-10-17 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system Protein Cell, 7, 2016
|
|
5E85
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e85 by Molmil](/molmil-images/mine/5e85) | isolated SBD of BiP | Descriptor: | 78 kDa glucose-regulated protein, SULFATE ION | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2015-12-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
|
|
5EB3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eb3 by Molmil](/molmil-images/mine/5eb3) | VB6-bound protein | Descriptor: | 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, SULFATE ION, YfiR | Authors: | Xu, M, Yang, X, Yang, X.-A, Zhou, L, Liu, T.-Z, Fan, Z, Jiang, T. | Deposit date: | 2015-10-17 | Release date: | 2016-05-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system Protein Cell, 7, 2016
|
|
8GYM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gym by Molmil](/molmil-images/mine/8gym) | Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2022-09-23 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
|
|
8GZU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gzu by Molmil](/molmil-images/mine/8gzu) | Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2 | Descriptor: | 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ... | Authors: | Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2022-09-27 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
|
|
8FEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8feq by Molmil](/molmil-images/mine/8feq) | |
8FER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fer by Molmil](/molmil-images/mine/8fer) | |
6KXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kxw by Molmil](/molmil-images/mine/6kxw) | Crystal structure of human aquaporin AQP7 in bound to glycerol | Descriptor: | Aquaporin-7, GLYCEROL | Authors: | Zhang, L, Yao, D, Zhou, F, Zhang, Q, Zhou, L, Cao, Y. | Deposit date: | 2019-09-13 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | The structural basis for glycerol permeation by human AQP7 Sci Bull (Beijing), 66, 2020
|
|
3OTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3otf by Molmil](/molmil-images/mine/3otf) | Structural basis for the cAMP-dependent gating in human HCN4 channel | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L. | Deposit date: | 2010-09-11 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the cAMP-dependent gating in the human HCN4 channel. J.Biol.Chem., 285, 2010
|
|
3LRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lrb by Molmil](/molmil-images/mine/3lrb) | Structure of E. coli AdiC | Descriptor: | Arginine/agmatine antiporter | Authors: | Gao, X, Lu, F, Zhou, L, Shi, Y. | Deposit date: | 2010-02-10 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Structure and mechanism of an amino acid antiporter Science, 324, 2009
|
|
3LRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lrc by Molmil](/molmil-images/mine/3lrc) | Structure of E. coli AdiC (P1) | Descriptor: | Arginine/agmatine antiporter | Authors: | Gao, X, Lu, F, Zhou, L, Shi, Y. | Deposit date: | 2010-02-11 | Release date: | 2010-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.004 Å) | Cite: | Structure and mechanism of an amino acid antiporter Science, 324, 2009
|
|
6ASY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6asy by Molmil](/molmil-images/mine/6asy) | BiP-ATP2 | Descriptor: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | Authors: | Liu, Q, Yang, J, Zong, Y, Columbus, L, Zhou, L. | Deposit date: | 2017-08-26 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s. Nat Commun, 8, 2017
|
|
3I9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3i9z by Molmil](/molmil-images/mine/3i9z) | Crystal structure of a metallochaperone with a trinuclear Cu(I) cluster | Descriptor: | COPPER (I) ION, Copper chaperone copZ | Authors: | Hearnshaw, S.J, Zhou, L, Le Brun, N.E, Hemmings, A.M. | Deposit date: | 2009-07-13 | Release date: | 2009-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA. Biochem.J., 424, 2009
|
|
3L1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l1l by Molmil](/molmil-images/mine/3l1l) | Structure of Arg-bound Escherichia coli AdiC | Descriptor: | ARGININE, Arginine/agmatine antiporter, nonyl beta-D-glucopyranoside | Authors: | Gao, X, Zhou, L, Shi, Y. | Deposit date: | 2009-12-13 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Mechanism of substrate recognition and transport by an amino acid antiporter Nature, 463, 2010
|
|