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2GLN
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BU of 2gln by Molmil
Crystal structure of Mycobacterium tuberculosis trHbN, GlnE11Ala mutant
Descriptor: CYANIDE ION, Hemoglobin-like protein HbN, PHOSPHATE ION, ...
Authors:Milani, M, Bolognesi, M.
Deposit date:2006-04-05
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2GKM
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BU of 2gkm by Molmil
Crystal structure of Mycobacterium tuberculosis trHbN TyrB10Phe mutant
Descriptor: CYANIDE ION, Hemoglobin-like protein HbN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Milani, M, Bolognesi, M.
Deposit date:2006-04-03
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.731 Å)
Cite:Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
5CSB
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BU of 5csb by Molmil
The crystal structure of beta2-microglobulin D76N mutant at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.719 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CS7
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BU of 5cs7 by Molmil
The crystal structure of wt beta2-microglobulin at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
2GKN
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BU of 2gkn by Molmil
Crystal structure of Mycobacterium tuberculosis trHbN, GlnE11Val mutant
Descriptor: CYANIDE ION, Hemoglobin-like protein HbN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Milani, M, Bolognesi, M.
Deposit date:2006-04-03
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2GL3
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BU of 2gl3 by Molmil
Crystal structure of Mycobacterium tuberculosis trHbN, TyrB10Phe GlnE11Val mutant
Descriptor: CYANIDE ION, Hemoglobin-like protein HbN, PHOSPHATE ION, ...
Authors:Milani, M, Bolognesi, M.
Deposit date:2006-04-04
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues
Biochemistry, 45, 2006
2QEQ
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BU of 2qeq by Molmil
Crystal structure of kunjin virus ns3 helicase
Descriptor: Flavivirin protease NS3 catalytic subunit
Authors:Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2007-06-26
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
J.Mol.Biol., 372, 2007
2HU2
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BU of 2hu2 by Molmil
CTBP/BARS in ternary complex with NAD(H) and RRTGAPPAL peptide
Descriptor: 9-mer peptide from Zinc finger protein 217, C-terminal-binding protein 1, FORMIC ACID, ...
Authors:Nardini, M, Bolognesi, M, Quinlan, K.G.R, Verger, A, Francescato, P, Crossley, M.
Deposit date:2006-07-26
Release date:2006-10-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins
Mol.Cell.Biol., 26, 2006
2OK7
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BU of 2ok7 by Molmil
Ferredoxin-NADP+ reductase from Plasmodium falciparum with 2'P-AMP
Descriptor: ADENOSINE-2'-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Putative ferredoxin--NADP reductase, ...
Authors:Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2007-01-16
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis.
J.Mol.Biol., 367, 2007
2OK8
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BU of 2ok8 by Molmil
Ferredoxin-NADP+ reductase from Plasmodium falciparum
Descriptor: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Putative ferredoxin--NADP reductase
Authors:Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2007-01-16
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis.
J.Mol.Biol., 367, 2007
7ZCE
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BU of 7zce by Molmil
SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Chaves-Sanjuan, A, Bolognesi, M.
Deposit date:2022-03-28
Release date:2022-10-12
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.
Mol.Ther., 31, 2022
7ZCF
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BU of 7zcf by Molmil
SARS-CoV-2 Spike RBD in complex with the single chain fragment scFv76 (Focused Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, scFv76 single chain fragment
Authors:Chaves-Sanjuan, A, Bolognesi, M.
Deposit date:2022-03-28
Release date:2022-10-12
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery.
Mol.Ther., 31, 2022
8A11
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BU of 8a11 by Molmil
Cryo-EM structure of the Human SHMT1-RNA complex
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, cytosolic
Authors:Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F.
Deposit date:2022-05-30
Release date:2023-06-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Cryo-EM structure of the Human SHMT1-RNA complex
To Be Published
1FCS
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BU of 1fcs by Molmil
CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Rizzi, M, Bolognesi, M, Coda, A, Cutruzzola, F, Travaglini Allocatelli, C, Brancaccio, A, Brunori, M.
Deposit date:1993-04-20
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a distal site double mutant of sperm whale myoglobin at 1.6 A resolution.
FEBS Lett., 320, 1993
1RAV
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BU of 1rav by Molmil
RECOMBINANT AVIDIN
Descriptor: AVIDIN
Authors:Rosano, C, Arosio, P, Bolognesi, M.
Deposit date:1998-03-27
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli.
Eur.J.Biochem., 256, 1998
1NGK
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BU of 1ngk by Molmil
Crystallographic Structure of Mycobacterium tuberculosis Hemoglobin O
Descriptor: CYANIDE ION, Hemoglobin-like protein HbO, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Milani, M, Savard, P.-Y, Oullet, H, Ascenzi, P, Guertin, M, Bolognesi, M.
Deposit date:2002-12-17
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:A TyrCD1/TrpG8 hydrogen bond network and a TyrB10-TyrCD1 covalent link shape the heme distal site of Mycobacterium tuberculosis hemoglobin O
Proc.Natl.Acad.Sci.USA, 100, 2003
1BWS
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BU of 1bws by Molmil
CRYSTAL STRUCTURE OF GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE FROM ESCHERICHIA COLI A KEY ENZYME IN THE BIOSYNTHESIS OF GDP-L-FUCOSE
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE)
Authors:Rizzi, M, Tonetti, M, Flora, A.D, Bolognesi, M.
Deposit date:1998-09-25
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily.
Structure, 6, 1998
4KL1
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BU of 4kl1 by Molmil
HCN4 CNBD in complex with cGMP
Descriptor: ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ...
Authors:Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A.
Deposit date:2013-05-07
Release date:2014-04-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat.Chem.Biol., 10, 2014
1SWM
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BU of 1swm by Molmil
X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION
Descriptor: AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rizzi, M, Ascenzi, P, Coda, A, Brunori, M, Bolognesi, M.
Deposit date:1992-03-03
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution.
J.Mol.Biol., 217, 1991
4CSR
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BU of 4csr by Molmil
High resolution crystal structure of the histone fold dimer (NF-YB)-(NF-YC)
Descriptor: GLYCEROL, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA, NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA
Authors:Gnesutta, N, Cocolo, S, Mantovani, R, Bolognesi, M, Nardini, M.
Deposit date:2014-03-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High Resolution Crystal Structure of the Histone Fold Dimer (NF-Yb)-(NF-Yc)
To be Published
4NRT
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BU of 4nrt by Molmil
Human Norovirus polymerase bound to Compound 6 (suramin derivative)
Descriptor: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, hNV-RdRp
Authors:Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Milani, M, Bolognesi, M.
Deposit date:2013-11-27
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4O4R
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BU of 4o4r by Molmil
Murine Norovirus RdRp in complex with PPNDS
Descriptor: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION
Authors:Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E.
Deposit date:2013-12-19
Release date:2014-11-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014
4NRU
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BU of 4nru by Molmil
Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative
Descriptor: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, RNA dependent RNA polymerase
Authors:Milani, M, Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Bolognesi, M.
Deposit date:2013-11-27
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
2BK9
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BU of 2bk9 by Molmil
Drosophila Melanogaster globin
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, CG9734-PA, CHLORIDE ION, ...
Authors:de Sanctis, D, Dewilde, S, Pesce, A, Moens, L, Ascenzi, P, Hankeln, T, Burmester, T, Ponassi, M, Nardini, M, Bolognesi, M.
Deposit date:2005-02-14
Release date:2005-05-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Bishistidyl Heme Hexacoordination, a Key Structural Property in Drosophila Melanogaster Hemoglobin
J.Biol.Chem., 280, 2005
1OAJ
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BU of 1oaj by Molmil
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase
Descriptor: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION
Authors:Cioni, P, Pesce, A, Rocca, B.M.D, Castelli, S, Falconi, M, Parrilli, L, Bolognesi, M, Strambini, G, Desideri, A.
Deposit date:2003-01-14
Release date:2003-02-27
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Active-Site Copper and Zinc Ions Modulate the Quaternary Structure of Prokaryotic Cu,Zn Superoxide Dismutase
J.Mol.Biol., 326, 2003

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