3J5Y
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![BU of 3j5y by Molmil](/molmil-images/mine/3j5y) | Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | Descriptor: | 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ... | Authors: | des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2013-11-21 | Release date: | 2013-12-25 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP. Nucleic Acids Res., 42, 2014
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1FCX
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![BU of 1fcx by Molmil](/molmil-images/mine/1fcx) | ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394 | Descriptor: | 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 | Authors: | Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) | Deposit date: | 2000-07-19 | Release date: | 2000-09-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J.Mol.Biol., 302, 2000
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3K2J
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![BU of 3k2j by Molmil](/molmil-images/mine/3k2j) | Crystal Structure of the 3rd Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) | Descriptor: | CHLORIDE ION, Protein polybromo-1, SULFATE ION | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Chaikuad, A, Pike, A.C.W, Krojer, T, Sethi, R, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-30 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the 3rd Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) To be Published
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1FGU
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![BU of 1fgu by Molmil](/molmil-images/mine/1fgu) | |
5CFJ
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![BU of 5cfj by Molmil](/molmil-images/mine/5cfj) | Structural and functional attributes of malaria parasite Ap4A hydrolase | Descriptor: | BIS(5'-nucleosyl)-tetraphosphatase (Diadenosine tetraphosphatase), putative, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sharma, A, Yogavel, M, Sharma, A. | Deposit date: | 2015-07-08 | Release date: | 2016-02-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural and functional attributes of malaria parasite diadenosine tetraphosphate hydrolase Sci Rep, 6, 2016
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3ZTN
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![BU of 3ztn by Molmil](/molmil-images/mine/3ztn) | STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY LIGHT CHAIN, ... | Authors: | Hubbard, P.A, Ritchie, A.J, Corti, D, Voss, J.E, Gamblin, S.J, Codoni, G, Macagno, A, Jarrossay, D, Pinna, D, Minola, A, Vanzetta, F, Silacci, C, Fernandez-Rodriguez, B.M, Agatic, G, Giacchetto-Sasselli, I, Vachieri, S.G, Sallusto, F, Collins, P.J, Haire, L.F, Temperton, N, Langedijk, J.P.M, Skehel, J.J, Lanzavecchia, A. | Deposit date: | 2011-07-12 | Release date: | 2011-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins. Science, 333, 2011
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2K2P
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![BU of 2k2p by Molmil](/molmil-images/mine/2k2p) | Solution NMR structure of protein Atu1203 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium (NESG) target AtT10, Ontario Center for Structural Proteomics target ATC1183 | Descriptor: | Uncharacterized protein Atu1203 | Authors: | Lemak, A, Gutmanas, A, Yee, A, Semesi, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-04-08 | Release date: | 2008-04-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of protein Atu1203 from Agrobacterium tumefaciens. To be Published
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3JTZ
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![BU of 3jtz by Molmil](/molmil-images/mine/3jtz) | Structure of the arm-type binding domain of HPI integrase | Descriptor: | Integrase, SODIUM ION | Authors: | Szwagierczak, A, Antonenka, U, Popowicz, G.M, Sitar, T, Holak, T.A, Rakin, A. | Deposit date: | 2009-09-14 | Release date: | 2009-10-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of the arm-type binding domains of HPI and HAI7 integrases J.Biol.Chem., 284, 2009
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3R02
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![BU of 3r02 by Molmil](/molmil-images/mine/3r02) | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors | Descriptor: | 7-[(cis-4-aminocyclohexyl)amino]-5-bromo-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 | Authors: | Xiang, Y, Hirth, B, Asmussen, G, Biemann, H.-P, Good, A, Fitzgerald, M, Gladysheva, T, Jancsics, K, Liu, J, Metz, M, Papoulis, A, Skerlj, R, Stepp, D.J, Wei, R.R. | Deposit date: | 2011-03-07 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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4YEH
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![BU of 4yeh by Molmil](/molmil-images/mine/4yeh) | Crystal structure of Mg2+ ion containing hemopexin fold from Kabuli chana (chickpea white) at 2.45A resolution reveals a structural basis of metal ion transport | Descriptor: | Lectin, MAGNESIUM ION | Authors: | Kumar, S, Singh, A, Yamini, S, Bhushan, A, Dey, S, Sharma, S, Singh, T.P. | Deposit date: | 2015-02-24 | Release date: | 2015-03-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal Structure of Mg(2+) Containing Hemopexin-Fold Protein from Kabuli Chana (Chickpea-White, CW-25) at 2.45 angstrom Resolution Reveals Its Metal Ion Transport Property Protein J., 34, 2015
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4H8J
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![BU of 4h8j by Molmil](/molmil-images/mine/4h8j) | Structure of GluA2-LBD in complex with MES | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutamate receptor 2, ... | Authors: | Reiter, A, Skerra, A, Trauner, D, Schiefner, A. | Deposit date: | 2012-09-22 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of an artificial photoreceptor To be Published
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6S90
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![BU of 6s90 by Molmil](/molmil-images/mine/6s90) | BTK in complex with an inhibitor | Descriptor: | 4-~{tert}-butyl-~{N}-[2-methyl-3-[6-[4-(4-methylpiperazin-1-yl)carbonylphenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]benzamide, Tyrosine-protein kinase BTK | Authors: | Gutmann, S, Hinniger, A. | Deposit date: | 2019-07-11 | Release date: | 2019-09-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation. Acs Med.Chem.Lett., 10, 2019
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3JZJ
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![BU of 3jzj by Molmil](/molmil-images/mine/3jzj) | Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium. | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Acarbose/maltose binding protein GacH, SULFATE ION | Authors: | Vahedi-Faridi, A, Licht, A, Bulut, H, Schneider, E. | Deposit date: | 2009-09-23 | Release date: | 2010-02-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium. J.Mol.Biol., 397, 2010
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4YN8
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![BU of 4yn8 by Molmil](/molmil-images/mine/4yn8) | Crystal Structure of Response Regulator ChrA in Heme-Sensing Two Component System | Descriptor: | MAGNESIUM ION, Response regulator ChrA, SULFATE ION | Authors: | Doi, A, Nakamura, H, Shiro, Y, Sugimoto, H. | Deposit date: | 2015-03-09 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the response regulator ChrA in the haem-sensing two-component system of Corynebacterium diphtheriae. Acta Crystallogr.,Sect.F, 71, 2015
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7AKR
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![BU of 7akr by Molmil](/molmil-images/mine/7akr) | |
7AKS
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![BU of 7aks by Molmil](/molmil-images/mine/7aks) | |
5CFI
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![BU of 5cfi by Molmil](/molmil-images/mine/5cfi) | |
5CHT
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![BU of 5cht by Molmil](/molmil-images/mine/5cht) | Crystal structure of USP18 | Descriptor: | Ubl carboxyl-terminal hydrolase 18, ZINC ION | Authors: | Fritz, G, Basters, A. | Deposit date: | 2015-07-10 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of the specificity of USP18 toward ISG15. Nat. Struct. Mol. Biol., 24, 2017
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1K5D
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![BU of 1k5d by Molmil](/molmil-images/mine/1k5d) | Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex | Descriptor: | GTP-binding nuclear protein RAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R. | Deposit date: | 2001-10-10 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | RanGAP mediates GTP hydrolysis without an arginine finger. Nature, 415, 2002
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1FAI
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![BU of 1fai by Molmil](/molmil-images/mine/1fai) | THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY | Descriptor: | IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN) | Authors: | Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A. | Deposit date: | 1992-05-27 | Release date: | 1992-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody. Proc.Natl.Acad.Sci.USA, 89, 1992
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3JU0
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![BU of 3ju0 by Molmil](/molmil-images/mine/3ju0) | Structure of the arm-type binding domain of HAI7 integrase | Descriptor: | Phage integrase | Authors: | Szwagierczak, A, Antonenka, U, Popowicz, G.M, Sitar, T, Holak, T.A, Rakin, A. | Deposit date: | 2009-09-14 | Release date: | 2009-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of the arm-type binding domains of HPI and HAI7 integrases J.Biol.Chem., 284, 2009
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2WEJ
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![BU of 2wej by Molmil](/molmil-images/mine/2wej) | Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors | Descriptor: | CARBONIC ANHYDRASE 2, GLYCEROL, ZINC ION, ... | Authors: | Scott, A.D, Phillips, C, Alex, A, Bent, A, O'Brien, R, Damian, L, Jones, L.H. | Deposit date: | 2009-03-31 | Release date: | 2009-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Thermodynamic Optimisation in Drug Discovery: A Case Study Using Carbonic Anhydrase Inhibitors. Chemmedchem, 4, 2009
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3J7H
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![BU of 3j7h by Molmil](/molmil-images/mine/3j7h) | Structure of beta-galactosidase at 3.2-A resolution obtained by cryo-electron microscopy | Descriptor: | Beta-galactosidase, MAGNESIUM ION | Authors: | Bartesaghi, A, Matthies, D, Banerjee, S, Merk, A, Subramaniam, S. | Deposit date: | 2014-06-30 | Release date: | 2014-07-30 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 111, 2014
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5CNN
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![BU of 5cnn by Molmil](/molmil-images/mine/5cnn) | Crystal structure of the EGFR kinase domain mutant I682Q | Descriptor: | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Kovacs, E, Das, R, Mirza, A, Jura, N, Barros, T, Kuriyan, J. | Deposit date: | 2015-07-17 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol.Cell.Biol., 35, 2015
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3JZA
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![BU of 3jza by Molmil](/molmil-images/mine/3jza) | Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila | Descriptor: | PHOSPHATE ION, Ras-related protein Rab-1B, Uncharacterized protein DrrA | Authors: | Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A. | Deposit date: | 2009-09-23 | Release date: | 2010-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol.Cell, 36, 2009
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