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2KWJ
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BU of 2kwj by Molmil
Solution structures of the double PHD fingers of human transcriptional protein DPF3 bound to a histone peptide containing acetylation at lysine 14
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-12
Release date:2010-07-14
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2KFT
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BU of 2kft by Molmil
NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide
Descriptor: Autoimmune regulator, Histone H3, ZINC ION
Authors:Chakravarty, S, Zeng, L, Zhou, M.
Deposit date:2009-02-27
Release date:2009-04-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator.
Structure, 17, 2009
2LSP
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BU of 2lsp by Molmil
solution structures of BRD4 second bromodomain with NF-kB-K310ac peptide
Descriptor: Bromodomain-containing protein 4, NF-kB-K310ac peptide
Authors:Zhang, G, Liu, R, Zhong, Y, Plotnikov, A.N, Zhang, W, Rusinova, E, Gerona-Nevarro, G, Moshkina, N, Joshua, J, Chuang, P.Y, Ohlmeyer, M, He, J, Zhou, M.-M.
Deposit date:2012-05-03
Release date:2012-07-18
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
J.Biol.Chem., 287, 2012
2L85
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BU of 2l85 by Molmil
Solution NMR structures of CBP bromodomain with small molecule of HBS
Descriptor: 4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid, CREB-binding protein
Authors:Borah, J.C, Mujtaba, S, Karakikes, I, Zeng, L, Muller, M, Patel, J, Moshkina, N, Morohashi, K, Zhang, W, Gerona-Navarro, G, Hajjar, R.J, Zhou, M.
Deposit date:2011-01-04
Release date:2011-01-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes.
Chem.Biol., 18, 2011
3QB8
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BU of 3qb8 by Molmil
Paramecium Chlorella Bursaria Virus1 Putative ORF A654L is a Polyamine Acetyltransferase
Descriptor: A654L protein, COENZYME A, IMIDAZOLE
Authors:Charlop-Powers, Z, Zhou, M.-M, Jakoncic, J, Gurnon, J, Van Etten, J.
Deposit date:2011-01-12
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Paramecium bursaria chlorella virus 1 encodes a polyamine acetyltransferase.
J. Biol. Chem., 287, 2012
2LXE
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BU of 2lxe by Molmil
S4wyild
Descriptor: Histone-lysine N-methyltransferase SUVR4
Authors:Kristiansen, P, Rahman, M.A, Aalen, R.B.
Deposit date:2012-08-20
Release date:2013-11-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure.
Biochemistry, 53, 2014
2KTB
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BU of 2ktb by Molmil
Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated peptide from Histone 3
Descriptor: H3_Peptide, Protein polybromo-1
Authors:Charlop-Powers, Z, Zhang, Q, Zeng, L.
Deposit date:2010-01-26
Release date:2010-05-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2.
Cell Res., 20, 2010
5Z9C
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BU of 5z9c by Molmil
Solution NMR structures of BRD4 first bromodomain with small compound MMQO
Descriptor: 8-methoxy-6-methylquinolin-4(1H)-one, Bromodomain-containing protein 4
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2018-02-02
Release date:2018-02-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.
J. Virol., 92, 2018
7CNA
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BU of 7cna by Molmil
Crystal structure of Spindlin1/C11orf84 complex bound to histone H3K4me3K9me3 peptide
Descriptor: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-GLY, ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER-THR, BENZAMIDINE, ...
Authors:Qian, C.M.
Deposit date:2020-07-30
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation.
Nat Commun, 12, 2021
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
Descriptor: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
Authors:Konuma, T, Zhou, M.-M.
Deposit date:2023-01-26
Release date:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
4QB3
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BU of 4qb3 by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with Olinone
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[4-(1-oxo-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)butyl]acetamide
Authors:Plotnikov, A.N, Joshua, J, Zhou, M.-M.
Deposit date:2014-05-06
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.
Chem.Biol., 21, 2014
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