8ER0
 
 | | X-ray crystal structure of Tet(X6) bound to anhydrotetracycline | | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | | Authors: | Kumar, H, Tolia, N.H. | | Deposit date: | 2022-10-11 | | Release date: | 2023-04-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
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8ER1
 | | X-ray crystal structure of Tet(X6) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | | Authors: | Kumar, H, Tolia, N.H. | | Deposit date: | 2022-10-11 | | Release date: | 2023-04-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
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1Z25
 | | Structure of P.furiosus Argonaute with bound Mn2+ | | Descriptor: | Argonaute, MANGANESE (II) ION | | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2005-03-07 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
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1Z26
 | | Structure of Pyrococcus furiosus Argonaute with bound tungstate | | Descriptor: | Argonaute, TUNGSTATE(VI)ION | | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2005-03-07 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
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8DCE
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8EZL
 | | Pfs25 in complex with transmission-reducing antibody AS01-50 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ... | | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-11-01 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
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8EZM
 | | Pfs25 in complex with transmission-reducing antibody AS01-63 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ... | | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-11-01 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
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8EZK
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5TUE
 | | Crystal structure of tetracycline destructase Tet(50) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Tetracycline destructase Tet(50) | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-05 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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5TUK
 | | Crystal structure of tetracycline destructase Tet(51) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Tetracycline destructase Tet(51) | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-06 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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5TUF
 | | Crystal structure of tetracycline destructase Tet(50) in complex with anhydrotetracycline | | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-06 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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5TUL
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5TUI
 | | Crystal structure of tetracycline destructase Tet(50) in complex with chlortetracycline | | Descriptor: | 7-CHLOROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-06 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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5TUM
 | | Crystal structure of tetracycline destructase Tet(56) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, tetracycline destructase Tet(56) | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2016-11-06 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.299 Å) | | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes.
Nat. Chem. Biol., 13, 2017
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8TWG
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8TWF
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5JQI
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7JUM
 | | Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01 | | Descriptor: | Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv | | Authors: | Tolia, N, Tang, W.K. | | Deposit date: | 2020-08-20 | | Release date: | 2021-03-31 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Nat Commun, 12, 2021
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5JR4
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7Q3N
 | | Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ... | | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | | Deposit date: | 2021-10-28 | | Release date: | 2022-03-16 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
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