1Z25

Structure of P.furiosus Argonaute with bound Mn2+

Summary for 1Z25

Entry DOI	10.2210/pdb1z25/pdb
Related	1U04 1Z26
Descriptor	Argonaute, MANGANESE (II) ION (3 entities in total)
Functional Keywords	argonaute, piwi, active site, rnaseh, mg2+, rnai, gene regulation
Biological source	Pyrococcus furiosus
Total number of polymer chains	1
Total formula weight	90652.11
Authors	Rivas, F.V.,Tolia, N.H.,Song, J.J.,Aragon, J.P.,Liu, J.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2005-03-07, release date: 2005-04-05, Last modification date: 2024-02-14)
Primary citation	Rivas, F.V.,Tolia, N.H.,Song, J.J.,Aragon, J.P.,Liu, J.,Hannon, G.J.,Joshua-Tor, L. Purified Argonaute2 and an siRNA form recombinant human RISC. Nat.Struct.Mol.Biol., 12:340-349, 2005 Cited by PubMed: 15800637 DOI: 10.1038/nsmb918 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation