Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2F6X
DownloadVisualize
BU of 2f6x by Molmil
Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with sn-G1P and MPD
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase, SN-GLYCEROL-1-PHOSPHATE
Authors:Payandeh, J.M.
Deposit date:2005-11-29
Release date:2006-01-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
J.Biol.Chem., 281, 2006
6X2J
DownloadVisualize
BU of 6x2j by Molmil
Structure of human TRPA1 in complex with agonist GNE551
Descriptor: 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide, Transient receptor potential cation channel subfamily A member 1
Authors:Rohou, A, Rouge, L, Chen, H.
Deposit date:2020-05-20
Release date:2020-11-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Neuron, 109, 2021
6WJ5
DownloadVisualize
BU of 6wj5 by Molmil
Structure of human TRPA1 in complex with inhibitor GDC-0334
Descriptor: (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide, Transient receptor potential cation channel subfamily A member 1
Authors:Rohou, A, Rouge, L, Arthur, C.P, Volgraf, M, Chen, H.
Deposit date:2020-04-11
Release date:2021-02-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J.Exp.Med., 218, 2021
8TLM
DownloadVisualize
BU of 8tlm by Molmil
Structure of a class A GPCR/Fab complex
Descriptor: C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ...
Authors:Sun, D, Johnson, M, Masureel, M.
Deposit date:2023-07-27
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8U1U
DownloadVisualize
BU of 8u1u by Molmil
Structure of a class A GPCR/agonist complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Sun, D, Johnson, M, Masureel, M.
Deposit date:2023-09-02
Release date:2023-12-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
6VJA
DownloadVisualize
BU of 6vja by Molmil
Structure of CD20 in complex with rituximab Fab
Descriptor: B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, Rituximab Fab heavy chain, ...
Authors:Rohou, A, Croll, T.I.
Deposit date:2020-01-15
Release date:2020-02-26
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab.
Science, 367, 2020
8U32
DownloadVisualize
BU of 8u32 by Molmil
Crystal structure of PD-1 in complex with a Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Sun, D, Masureel, M.
Deposit date:2023-09-07
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
8U31
DownloadVisualize
BU of 8u31 by Molmil
Crystal structure of PD-1 in complex with a Fab
Descriptor: Fab heavy chain, Fab light chain, GLYCEROL, ...
Authors:Sun, D, Masureel, M.
Deposit date:2023-09-07
Release date:2024-06-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
8W0S
DownloadVisualize
BU of 8w0s by Molmil
Human EBP complexed with compound 3a
Descriptor: 1-methyl-8-[(oxan-4-yl)methyl]-3-[4-(trifluoromethyl)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Authors:Sun, D, Masureel, M.
Deposit date:2024-02-14
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation.
J.Med.Chem., 67, 2024
8W0R
DownloadVisualize
BU of 8w0r by Molmil
Human EBP complexed with compound 1
Descriptor: 1-methyl-1'-[(oxan-4-yl)methyl]-5-(trifluoromethyl)spiro[indole-2,4'-piperidin]-3(1H)-one, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Authors:Sun, D, Masureel, M.
Deposit date:2024-02-14
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation.
J.Med.Chem., 67, 2024
4EEB
DownloadVisualize
BU of 4eeb by Molmil
CorA coiled-coil mutant under Mg2+ absence
Descriptor: CESIUM ION, Magnesium transport protein CorA, SODIUM ION
Authors:Pfoh, R, Pai, E.F.
Deposit date:2012-03-28
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EED
DownloadVisualize
BU of 4eed by Molmil
CorA coiled-coil mutant under Mg2+ presence
Descriptor: MAGNESIUM ION, Magnesium transport protein CorA
Authors:Pfoh, R, Pai, E.F.
Deposit date:2012-03-28
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.
Proc.Natl.Acad.Sci.USA, 109, 2012
7T99
DownloadVisualize
BU of 7t99 by Molmil
Crystal structure of engineered CYS-CYS fab dimer CL-205 (LC25)
Descriptor: FAB Heavy Chain, FAB Light Chain, PHOSPHATE ION
Authors:Harris, S.F, Boenig, G.D.L.
Deposit date:2021-12-18
Release date:2022-10-12
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
7T98
DownloadVisualize
BU of 7t98 by Molmil
Crystal structure of engineered CYS-CYS fab dimer VL-108 (LC33)
Descriptor: FAB Heavy Chain, FAB Light Chain
Authors:Harris, S.F, Boenig, G.D.L.
Deposit date:2021-12-18
Release date:2022-10-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
7T97
DownloadVisualize
BU of 7t97 by Molmil
Crystal structure of engineered CYS-CYS fab dimer CH1-207 (HC4)
Descriptor: FAB Heavy chain, FAB Light Chain
Authors:Harris, S.F, Boenig, G.D.L.
Deposit date:2021-12-18
Release date:2022-10-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.144 Å)
Cite:Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
6C1P
DownloadVisualize
BU of 6c1p by Molmil
HypoPP mutant
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, Ion transport protein, ...
Authors:Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M.
Deposit date:2018-01-05
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
<123

 

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon