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7SJR
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BU of 7sjr by Molmil
Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP
Descriptor: DNA (70-MER), DNA helicase, IRON/SULFUR CLUSTER, ...
Authors:Wang, J, Warren, G.M, Shuman, S, Patel, D.J.
Deposit date:2021-10-18
Release date:2021-12-22
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.
Nucleic Acids Res., 50, 2022
7T02
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BU of 7t02 by Molmil
Cryo-EM structure of DNMT5 pseudo-ternary complex solved by incubation with hemimethylated DNA and SAM
Descriptor: DNA (5'-D(*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), DNA repair protein Rad8, ...
Authors:Wang, J, Patel, D.J.
Deposit date:2021-11-29
Release date:2022-02-23
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance.
Mol.Cell, 82, 2022
3SUH
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BU of 3suh by Molmil
Crystal structure of THF riboswitch, bound with 5-formyl-THF
Descriptor: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, Riboswitch, SODIUM ION
Authors:Huang, L, Serganov, A, Patel, D.J.
Deposit date:2011-07-11
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SOW
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BU of 3sow by Molmil
Structure of UHRF1 PHD finger in complex with histone H3K4me3 1-9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E, Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9501 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
3SUX
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BU of 3sux by Molmil
Crystal structure of THF riboswitch, bound with THF
Descriptor: 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID, Riboswitch, SODIUM ION
Authors:Huang, L, Serganov, A, Patel, D.J.
Deposit date:2011-07-11
Release date:2011-09-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SUY
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BU of 3suy by Molmil
Crystal structure of THF riboswitch, unbound status
Descriptor: riboswitch
Authors:Huang, L, Serganov, A, Patel, D.J.
Deposit date:2011-07-11
Release date:2011-09-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SLQ
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BU of 3slq by Molmil
Crystal structure of the 2'- Deoxyguanosine riboswitch bound to guanosine-5'-monophosphate
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, RNA (68-MER), SUCCINIC ACID, ...
Authors:Pikovskaya, O, Polonskaia, A, Patel, D.J, Serganov, A.
Deposit date:2011-06-24
Release date:2011-08-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.
Nat.Chem.Biol., 7, 2011
3SKR
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BU of 3skr by Molmil
Crystal structure of the 2'- Deoxyguanosine riboswitch bound to 2'- Deoxyguanosine, cobalt Hexammine soak
Descriptor: 2'-DEOXY-GUANOSINE, COBALT HEXAMMINE(III), MAGNESIUM ION, ...
Authors:Pikovskaya, O, Polonskaia, A, Patel, D.J, Serganov, A.
Deposit date:2011-06-23
Release date:2011-08-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.
Nat.Chem.Biol., 7, 2011
3SKZ
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BU of 3skz by Molmil
Crystal structure of the 2'- deoxyguanosine riboswitch bound to guanosine
Descriptor: GUANOSINE, MAGNESIUM ION, RNA (68-MER), ...
Authors:Pikovskaya, O, Polonskaia, A, Patel, D.J, Serganov, A.
Deposit date:2011-06-23
Release date:2011-08-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.
Nat.Chem.Biol., 7, 2011
2EVD
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BU of 2evd by Molmil
Crystal structure of human Glycolipid Transfer Protein complexed with 12:0 Lactosylceramide
Descriptor: DECANE, Glycolipid transfer protein, LAURIC ACID, ...
Authors:Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J.
Deposit date:2005-10-31
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
2EVL
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BU of 2evl by Molmil
Crystal structure of human Glycolipid Transfer Protein complexed with 18:2 Galactosylceramide
Descriptor: Glycolipid transfer protein, LINOLEIC ACID, N-OCTANE, ...
Authors:Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J.
Deposit date:2005-10-31
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
2EUM
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BU of 2eum by Molmil
Crystal structure of human Glycolipid Transfer Protein complexed with 8:0 Lactosylceramide
Descriptor: DECANE, Glycolipid transfer protein, N-OCTANE, ...
Authors:Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J.
Deposit date:2005-10-28
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
3VRS
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BU of 3vrs by Molmil
Crystal structure of fluoride riboswitch, soaked in Mn2+
Descriptor: FLUORIDE ION, Fluoride riboswitch, MANGANESE (II) ION, ...
Authors:Ren, A.M, Rajashankar, K.R, Patel, D.J.
Deposit date:2012-04-13
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature, 486, 2012
2FSA
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BU of 2fsa by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
Descriptor: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor
Authors:Li, H, Patel, D.J.
Deposit date:2006-01-21
Release date:2006-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2FUI
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BU of 2fui by Molmil
NMR solution structure of PHD finger fragment of human BPTF in free state
Descriptor: bromodomain PHD finger transcription factor
Authors:Ilin, S, Patel, D.J.
Deposit date:2006-01-26
Release date:2006-07-11
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3SOU
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BU of 3sou by Molmil
Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E, Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8001 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
2F8T
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BU of 2f8t by Molmil
Crystal structure of Aa-Ago with externally-bound siRNA
Descriptor: 26-MER, Argonaute protein
Authors:Yuan, Y.R, Chen, H.Y, Patel, D.J.
Deposit date:2005-12-03
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA.
Structure, 14, 2006
2F6J
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BU of 2f6j by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
Descriptor: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3UII
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BU of 3uii by Molmil
crystal structure of human Survivin in complex with H3(1-10) peptide
Descriptor: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
Authors:Du, J, Patel, D.J.
Deposit date:2011-11-04
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
2FUU
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BU of 2fuu by Molmil
NMR solution structure of the PHD domain from the human BPTF in complex with H3(1-15)K4me3 peptide
Descriptor: Histone H3, ZINC ION, bromodomain PHD finger transcription factor
Authors:Ilin, S, Patel, D.J.
Deposit date:2006-01-27
Release date:2006-07-11
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2EVS
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BU of 2evs by Molmil
Crystal structure of human Glycolipid Transfer Protein complexed with n-hexyl-beta-D-glucoside
Descriptor: DECANE, Glycolipid transfer protein, HEXANE, ...
Authors:Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J.
Deposit date:2005-10-31
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
Plos Biol., 4, 2006
3U5M
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BU of 3u5m by Molmil
Crystal structure of TRIM33 PHD-Bromo in the free state
Descriptor: CALCIUM ION, E3 ubiquitin-protein ligase TRIM33, ZINC ION
Authors:Wang, Z, Patel, D.J.
Deposit date:2011-10-11
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
3UIG
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BU of 3uig by Molmil
crystal structure of human Survivin in complex with T3 phosphorylated H3(1-15) peptide
Descriptor: Baculoviral IAP repeat-containing protein 5, T3 phosphorylated H3(1-15) peptide, ZINC ION
Authors:Du, J, Patel, D.J.
Deposit date:2011-11-04
Release date:2012-02-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
2H6Q
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BU of 2h6q by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Descriptor: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
Authors:Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
Deposit date:2006-06-01
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GKU
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BU of 2gku by Molmil
Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures
Descriptor: Human telomere DNA
Authors:Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J.
Deposit date:2006-04-03
Release date:2006-08-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold.
J.Am.Chem.Soc., 128, 2006

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