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5JHN
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BU of 5jhn by Molmil
Structure of G9a SET-domain with Histone H3K9Ala mutant peptide and bound S-adenosylmethionine
Descriptor: Histone H3.1 peptide with K9A mutation, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
Authors:Jayaram, H, Bellon, S.F, Poy, F.
Deposit date:2016-04-21
Release date:2016-07-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JIN
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BU of 5jin by Molmil
Structure of G9a SET-domain with Histone H3K9M mutant peptide and bound S-adenosylmethionine
Descriptor: Histone H3.1 peptide with K9M mutation, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
Authors:Jayaram, H, Bellon, S.F, Poy, F.
Deposit date:2016-04-22
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JLE
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BU of 5jle by Molmil
Crystal structure of SETD2 bound to SAH
Descriptor: Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Li, H, Yang, S, Zheng, X.
Deposit date:2016-04-27
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Genes Dev., 30, 2016
5JLB
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BU of 5jlb by Molmil
Crystal structure of SETD2 bound to histone H3.3 K36I peptide
Descriptor: GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase SETD2, ...
Authors:Li, H, Yang, S.
Deposit date:2016-04-26
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Genes Dev., 30, 2016
5JIY
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BU of 5jiy by Molmil
Structure of G9a SET-domain with Histone H3K9norLeucine mutant peptide and bound S-adenosylmethionine
Descriptor: Histone H3.1 mutant peptide with H3K9nor-leucine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
Authors:Jayaram, H, Bellon, S.F, Poy, F.
Deposit date:2016-04-22
Release date:2016-09-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JJY
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BU of 5jjy by Molmil
Crystal structure of SETD2 bound to histone H3.3 K36M peptide
Descriptor: Histone H3.3, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Yang, S, Zheng, X, Li, H.
Deposit date:2016-04-25
Release date:2016-11-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Genes Dev., 30, 2016
2M0O
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BU of 2m0o by Molmil
The solution structure of human PHF1 in complex with H3K36me3
Descriptor: H3K36me3 peptide, PHD finger protein 1
Authors:Song, J, Patel, D.J.
Deposit date:2012-10-30
Release date:2013-01-16
Last modified:2013-02-27
Method:SOLUTION NMR
Cite:An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013
2PVC
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BU of 2pvc by Molmil
DNMT3L recognizes unmethylated histone H3 lysine 4
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, Histone H3 peptide, ZINC ION
Authors:Cheng, X.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Nature, 448, 2007
2PV0
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BU of 2pv0 by Molmil
DNA methyltransferase 3 like protein (DNMT3L)
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, ZINC ION
Authors:Cheng, X.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Nature, 448, 2007
3QL9
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BU of 3ql9 by Molmil
Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLN
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BU of 3qln by Molmil
Crystal structure of ATRX ADD domain in free state
Descriptor: Transcriptional regulator ATRX, ZINC ION
Authors:Li, H, Patel, D.J.
Deposit date:2011-02-03
Release date:2011-06-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLA
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BU of 3qla by Molmil
Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide
Descriptor: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ...
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QZS
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BU of 3qzs by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form I
Descriptor: Histone H4, Nucleosome-remodeling factor subunit BPTF
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3QZV
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BU of 3qzv by Molmil
Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide
Descriptor: Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3QLC
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BU of 3qlc by Molmil
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Li, H, Patel, D.J.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QZT
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BU of 3qzt by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II
Descriptor: GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
Descriptor: Histone demethylase JARID1A, ZINC ION
Authors:Song, J, Wang, Z, Patel, D.J.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KGI
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BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
Descriptor: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
Authors:Song, J, Wang, Z, Patel, D.J.
Deposit date:2009-03-12
Release date:2009-05-05
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KU7
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BU of 2ku7 by Molmil
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
Descriptor: MLL1 PHD3-Cyp33 RRM chimeric protein
Authors:Song, J, Wang, Z, Patel, D.
Deposit date:2010-02-12
Release date:2010-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
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