7Z94
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![BU of 7z94 by Molmil](/molmil-images/mine/7z94) | Crystal structure of Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with indole | Descriptor: | DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, INDOLE, ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-19 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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7Z4X
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7Z98
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![BU of 7z98 by Molmil](/molmil-images/mine/7z98) | Crystal structure of F191M variant Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with methyl phenyl sulfide | Descriptor: | (methylsulfanyl)benzene, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-20 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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7ZCA
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![BU of 7zca by Molmil](/molmil-images/mine/7zca) | Crystal structure of the F191M/F201A variant of Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with benzyl phenyl sulfoxide | Descriptor: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative dehydrogenase/oxygenase subunit (Flavoprotein), ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-26 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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7Z99
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7Z97
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![BU of 7z97 by Molmil](/molmil-images/mine/7z97) | Crystal structure of the F191M variant of Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with 6-bromoindole | Descriptor: | 1,2-ETHANEDIOL, 6-bromo-1H-indole, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-20 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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7X6K
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![BU of 7x6k by Molmil](/molmil-images/mine/7x6k) | SARS-CoV-2 3CL protease (3CLpro) in complex with compound 3w | Descriptor: | 1H-indole-2-carbaldehyde, 3C-like proteinase | Authors: | Su, H, Nie, T, Xie, H, Li, Z.W, Li, M.J, Xu, Y. | Deposit date: | 2022-03-07 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. J.Med.Chem., 65, 2022
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7X6J
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![BU of 7x6j by Molmil](/molmil-images/mine/7x6j) | SARS-CoV-2 3CL protease (3CLpro) in complex with compound 3af | Descriptor: | 3C-like proteinase, quinoline-2-carboxylic acid | Authors: | Su, H, Nie, T, Xie, H, Li, Z.W, Li, M.J, Xu, Y. | Deposit date: | 2022-03-07 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. J.Med.Chem., 65, 2022
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6CO3
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![BU of 6co3 by Molmil](/molmil-images/mine/6co3) | aducanumab abeta complex | Descriptor: | ALA-GLU-PHE-ARG-HIS-ASP, Fab heavy chain, Fab light chain, ... | Authors: | Arndt, J.W. | Deposit date: | 2018-03-10 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.384 Å) | Cite: | Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta. Sci Rep, 8, 2018
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6CNR
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![BU of 6cnr by Molmil](/molmil-images/mine/6cnr) | aducanumab apo Fab | Descriptor: | Aducanumab heavy chain, Aducanumab light chain, SULFATE ION | Authors: | Arndt, J.W. | Deposit date: | 2018-03-08 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta. Sci Rep, 8, 2018
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4EN2
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4EMZ
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8T33
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![BU of 8t33 by Molmil](/molmil-images/mine/8t33) | Crystal structure of K46 acetylated GABARAP in complex with the LIR of TP53INP2/DOR | Descriptor: | ACETATE ION, Gamma-aminobutyric acid receptor-associated protein, Tumor protein p53-inducible nuclear protein 2, ... | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8T32
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![BU of 8t32 by Molmil](/molmil-images/mine/8t32) | Crystal structure of K48 acetylated GABARAP in complex with the LIR of TP53INP2/DOR | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, LIR of DOR, TRIETHYLENE GLYCOL | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8T35
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![BU of 8t35 by Molmil](/molmil-images/mine/8t35) | Crystal structure of K51 acetylated LC3A in complex with the LIR of TP53INP2/DOR | Descriptor: | 1,2-ETHANEDIOL, Tumor protein p53-inducible nuclear protein 2,Microtubule-associated proteins 1A/1B light chain 3A | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8T36
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![BU of 8t36 by Molmil](/molmil-images/mine/8t36) | Crystal structure of K49 acetylated LC3A in complex with the LIR of TP53INP2/DOR | Descriptor: | 1,2-ETHANEDIOL, Tumor protein p53-inducible nuclear protein 2,Microtubule-associated proteins 1A/1B light chain 3A chimera | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.852 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8T31
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![BU of 8t31 by Molmil](/molmil-images/mine/8t31) | Crystal structure of GABARAP in complex with the LIR of TP53INP2/DOR | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, Tumor protein p53-inducible nuclear protein 2 | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-07 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8T4T
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![BU of 8t4t by Molmil](/molmil-images/mine/8t4t) | Crystal structure of LC3A in complex with the LIR of TP53INP2/DOR | Descriptor: | Tumor protein p53-inducible nuclear protein 2,Microtubule-associated proteins 1A/1B light chain 3A chimera | Authors: | Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G. | Deposit date: | 2023-06-10 | Release date: | 2024-05-22 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.359 Å) | Cite: | Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, 20, 2024
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8VK2
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![BU of 8vk2 by Molmil](/molmil-images/mine/8vk2) | X-ray crystal structure of human IgE 4C8 Fab | Descriptor: | IgE 4C8 heavy chain, IgE 4C8 light chain | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | Deposit date: | 2024-01-08 | Release date: | 2024-06-19 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.508 Å) | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 154, 2024
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8VK1
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![BU of 8vk1 by Molmil](/molmil-images/mine/8vk1) | X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103 | Descriptor: | Der p 2 variant 3, IgE 4C8 heavy chain, IgE 4C8 light chain | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | Deposit date: | 2024-01-08 | Release date: | 2024-06-19 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2. J.Allergy Clin.Immunol., 154, 2024
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8VY6
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![BU of 8vy6 by Molmil](/molmil-images/mine/8vy6) | Murine light chain dimer | Descriptor: | 6A8 light chain, SULFATE ION | Authors: | Kapingidza, A.B, Dolamore, C, Hyduke, N.P, Easly, W, Chivv, C, Pomes, A, Chruszcz, M. | Deposit date: | 2024-02-07 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural, Biophysical, and Computational Studies of a Murine Light Chain Dimer. Molecules, 29, 2024
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6F5M
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![BU of 6f5m by Molmil](/molmil-images/mine/6f5m) | Crystal structure of highly glycosylated human leukocyte elastase in complex with a thiazolidinedione inhibitor | Descriptor: | 5-[[4-[[(2~{S})-4-methyl-1-oxidanylidene-1-[(2-propylphenyl)amino]pentan-2-yl]carbamoyl]phenyl]methyl]-2-oxidanylidene-1,3-thiazol-1-ium-4-olate, ACETATE ION, Neutrophil elastase, ... | Authors: | Hochscherf, J, Pietsch, M, Tieu, W, Kuan, K, Hautmann, S, Abell, A, Guetschow, M, Niefind, K. | Deposit date: | 2017-12-01 | Release date: | 2018-08-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2' site binding inhibitor. Acta Crystallogr F Struct Biol Commun, 74, 2018
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8AJR
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![BU of 8ajr by Molmil](/molmil-images/mine/8ajr) | |
8ALQ
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7V90
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![BU of 7v90 by Molmil](/molmil-images/mine/7v90) | Telomeric mononucleosome | Descriptor: | DNA (145-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Soman, A. | Deposit date: | 2021-08-24 | Release date: | 2022-07-27 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Columnar structure of human telomeric chromatin. Nature, 609, 2022
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