8AJR
The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2
Summary for 8AJR
| Entry DOI | 10.2210/pdb8ajr/pdb |
| NMR Information | BMRB: 51020 |
| Descriptor | Methyl-CpG-binding protein 2 (1 entity in total) |
| Functional Keywords | epigenetic modifications, reader protein, domain of mecp2, gene regulation |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 11905.29 |
| Authors | Singh, H. (deposition date: 2022-07-28, release date: 2023-02-22, Last modification date: 2024-06-19) |
| Primary citation | Singh, H.,Das, C.K.,Buchmuller, B.C.,Schafer, L.V.,Summerer, D.,Linser, R. Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity. Nucleic Acids Res., 51:6495-6506, 2023 Cited by PubMed: 36919612DOI: 10.1093/nar/gkad134 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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