8T35

Crystal structure of K51 acetylated LC3A in complex with the LIR of TP53INP2/DOR

Summary for 8T35

Entry DOI	10.2210/pdb8t35/pdb
Related	8T2L 8T2M 8T2N
Descriptor	Tumor protein p53-inducible nuclear protein 2,Microtubule-associated proteins 1A/1B light chain 3A, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	autophagy, lc3a acetylation, dor lir, tp53ip2 lir, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	31766.25
Authors	Ali, M.G.H.,Wahba, H.M.,Cyr, N.,Omichinski, J.G. (deposition date: 2023-06-07, release date: 2024-05-22, Last modification date: 2024-06-05)
Primary citation	Ali, M.G.,Wahba, H.M.,Igelmann, S.,Cyr, N.,Ferbeyre, G.,Omichinski, J.G. Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy, :1-20, 2024 Cited by PubMed: 38726830 DOI: 10.1080/15548627.2024.2353443 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.902 Å)

Structure validation