9B4G
 
 | | Structure of inhibitor-bound human PSS1 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, (7P)-7-[(4S)-4-{4-[3,5-bis(trifluoromethyl)phenoxy]phenyl}-5-(2,2-difluoropropyl)-6-oxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-1,3-benzoxazol-2(3H)-one, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... | | Authors: | Long, T, Li, X. | | Deposit date: | 2024-03-20 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
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9B4F
 | | Structure of human PSS1-P269S | | Descriptor: | CALCIUM ION, Phosphatidylserine synthase 1 | | Authors: | Long, T, Li, X. | | Deposit date: | 2024-03-20 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
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9B4E
 | | Structure of wild type human PSS1 | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CALCIUM ION, ... | | Authors: | Long, T, Li, X. | | Deposit date: | 2024-03-20 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake.
Cell, 187, 2024
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4HCT
 | | Crystal structure of ITK in complex with compound 52 | | Descriptor: | 3-{1-[(3R)-1-acryloylpiperidin-3-yl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-N-(3-tert-butylphenyl)benzamide, Tyrosine-protein kinase ITK/TSK | | Authors: | Zapf, C.W, Gerstenberger, B.S, Xing, L, Limburg, D.C, Anderson, D.R, Caspers, N, Han, S, Aulabaugh, A, Kurumbail, R, Shakya, S, Li, X, Spaulding, V, Czerwinski, R.M, Seth, N, Medley, Q.G. | | Deposit date: | 2012-10-01 | | Release date: | 2012-11-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with nanomolar potency in a whole-blood assay.
J.Med.Chem., 55, 2012
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4HG9
 | | Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom | | Descriptor: | Basic phospholipase A2 B, CALCIUM ION, CITRIC ACID, ... | | Authors: | Zeng, F, Niu, L, Li, X, Teng, M. | | Deposit date: | 2012-10-07 | | Release date: | 2012-10-17 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom
TO BE PUBLISHED
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4IQ8
 | | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae | | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase 3 | | Authors: | Wang, H, Liu, Q, Niu, L, Teng, M, Li, X. | | Deposit date: | 2013-01-11 | | Release date: | 2013-02-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Preliminary crystallographic analysis of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 68, 2012
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4FQN
 | | Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD) | | Descriptor: | Malcavernin | | Authors: | Fisher, O.S, Zhang, R, Li, X, Murphy, J.W, Boggon, T.J. | | Deposit date: | 2012-06-25 | | Release date: | 2012-12-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.
Febs Lett., 587, 2013
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4GF8
 | | Crystal Structure of the Chitin Oligasaccharide Binding Protein | | Descriptor: | Peptide ABC transporter, periplasmic peptide-binding protein, SULFATE ION | | Authors: | Xu, S, Li, X, Gu, L, Roseman, R, Stock, A.M. | | Deposit date: | 2012-08-03 | | Release date: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Chitin catabolic cascade in the marine bacterium Vibrio cholerae: properties, structure and functions of a periplasmic chitooligosaccharide binding protein (CBP)
To be Published
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7Y9O
 | | Crystal structure of a CYP109B4 variant from Bacillus sonorensis | | Descriptor: | CALCIUM ION, Cytochrome P450 monooxygenase YjiB, IMIDAZOLE, ... | | Authors: | Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-25 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
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7Y97
 | | Crystal structure of CYP109B4 from Bacillus Sonorensis | | Descriptor: | Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-24 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
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7Y98
 | | Crystal structure of CYP109B4 from Bacillus Sonorensis in complex with Testosterone | | Descriptor: | Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE | | Authors: | Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-24 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
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4J1G
 | | Leanyer orthobunyavirus nucleoprotein-ssRNA complex | | Descriptor: | Nucleocapsid, RNA (45-MER) | | Authors: | Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J. | | Deposit date: | 2013-02-01 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.789 Å) | | Cite: | Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4H0S
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4IFS
 | | Crystal structure of the hSSRP1 Middle domain | | Descriptor: | CHLORIDE ION, FACT complex subunit SSRP1 | | Authors: | Zhang, W.J, Zeng, F.X, Shao, C, Liu, Y.W, Niu, L.W, Li, X, Teng, M.K. | | Deposit date: | 2012-12-15 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal structure of the hSSRP1 Middle domain
To be Published
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4J1J
 | | Leanyer orthobunyavirus nucleoprotein-ssDNA complex | | Descriptor: | DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3'), Nucleocapsid | | Authors: | Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J. | | Deposit date: | 2013-02-01 | | Release date: | 2013-04-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GFR
 | | Crystal Structure of the liganded Chitin Oligasaccharide Binding Protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, Peptide ABC transporter, ... | | Authors: | Xu, S, Li, X, Gu, L, Roseman, R, Stock, A.M. | | Deposit date: | 2012-08-03 | | Release date: | 2013-08-21 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Chitin catabolic cascade in the marine bacterium Vibrio cholerae: properties, structure and functions of a periplasmic chitooligosaccharide binding protein (CBP)
To be Published
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4KDR
 | | Crystal Structure of UBIG/SAH complex | | Descriptor: | 3-demethylubiquinone-9 3-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Zhu, Y, Teng, M, Li, X. | | Deposit date: | 2013-04-25 | | Release date: | 2014-04-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | Crystal Structure of the UBIG/SAH complex
To be Published
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8WLD
 | | Cryo-EM structure of SIR2/HerA antiphage complex | | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | Deposit date: | 2023-09-29 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Cryo-EM structure of SIR2/HerA antiphage complex
To Be Published
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8WIV
 | | Cryo-EM structure of a bacterial protein | | Descriptor: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Cryo-EM structure of a bacterial protein
To Be Published
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8WOC
 | | Cryo-EM structure of SIR2/HerA complex | | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | Deposit date: | 2023-10-07 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Cryo-EM structure of a bacterial protein
To Be Published
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8WOF
 | | Cryo-EM structure of SIR2/HerA complex | | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | Deposit date: | 2023-10-07 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of a bacterial protein
To Be Published
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8WOD
 | | Cryo-EM structure of SIR2/HerA complex | | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | Deposit date: | 2023-10-07 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Cryo-EM structure of a bacterial protein
To Be Published
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8WRB
 | | Lysophosphatidylserine receptor GPR34-Gi complex | | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Gong, W, Liu, G, Li, X, Wang, Y, Zhang, X. | | Deposit date: | 2023-10-13 | | Release date: | 2023-11-08 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174.
Plos Biol., 21, 2023
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8W9L
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8Y6V
 | | Near-atomic structure of icosahedrally averaged jumbo bacteriophage PhiKZ capsid | | Descriptor: | gp119, gp120, gp162, ... | | Authors: | Yang, Y, Shao, Q, Guo, M, Han, L, Zhao, X, Wang, A, Li, X, Wang, B, Pan, J, Chen, Z, Fokine, A, Sun, L, Fang, Q. | | Deposit date: | 2024-02-03 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Capsid structure of bacteriophage Phi KZ provides insights into assembly and stabilization of jumbo phages.
Nat Commun, 15, 2024
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