4N1L
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![BU of 4n1l by Molmil](/molmil-images/mine/4n1l) | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.986 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4N1K
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![BU of 4n1k by Molmil](/molmil-images/mine/4n1k) | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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4N1J
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![BU of 4n1j by Molmil](/molmil-images/mine/4n1j) | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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1OCI
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![BU of 1oci by Molmil](/molmil-images/mine/1oci) | [3.2.0]bcANA:DNA | Descriptor: | 5'-D(*CP*TP*GP*A TLBP*AP*TP*GP*CP)-3', 5'-D(*GP*CP*AP*TP*AP*TP*CP*AP*GP)-3' | Authors: | Tommerholt, H.V, Christensen, N.K, Nielsen, P, Wengel, J, Stein, P.C, Jacobsen, J.P, Petersen, M. | Deposit date: | 2003-02-07 | Release date: | 2003-07-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of a DsDNA Containing a Bicyclic D-Arabino-Configured Nucleotide Fixed in an O4'-Endo Sugar Conformation Org.Biomol.Chem., 1, 2003
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1KLA
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![BU of 1kla by Molmil](/molmil-images/mine/1kla) | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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1GV6
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![BU of 1gv6 by Molmil](/molmil-images/mine/1gv6) | Solution structure of alfa-L-LNA:DNA duplex | Descriptor: | 5- D(*CP*(ATL)P*GP*CP*(ATL)P*(ATL)P*CP*(ATL)P* GP*C) -3, 5- D(*GP*CP*AP*GP*AP*AP*GP*CP*AP*G) -3 | Authors: | Nielsen, K.M.E, Petersen, M, Haakansson, A.E, Wengel, J, Jacobsen, J.P. | Deposit date: | 2002-02-06 | Release date: | 2002-07-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Alfa-L-Lna (Alfa-L-Ribo Configured Locked Nucleic Acid) Recognition of DNA: An NMR Spectroscopic Study Chemistry, 8, 2002
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1KLC
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![BU of 1klc by Molmil](/molmil-images/mine/1klc) | SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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1KLD
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![BU of 1kld by Molmil](/molmil-images/mine/1kld) | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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7CLD
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![BU of 7cld by Molmil](/molmil-images/mine/7cld) | Crystal structure of T2R-TTL-Cevipabulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, CALCIUM ION, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-07-20 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Cevipabulin-tubulin complex reveals a novel agent binding site on alpha-tubulin with tubulin degradation effect. Sci Adv, 7, 2021
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3ENI
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![BU of 3eni by Molmil](/molmil-images/mine/3eni) | Crystal structure of the Fenna-Matthews-Olson Protein from Chlorobaculum Tepidum | Descriptor: | BACTERIOCHLOROPHYLL A, Bacteriochlorophyll a protein | Authors: | Tronrud, D, Camara-Artigas, A, Blankenship, R, Allen, J.P. | Deposit date: | 2008-09-25 | Release date: | 2009-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structural basis for the difference in absorbance spectra for the FMO antenna protein from various green sulfur bacteria. Photosynth.Res., 100, 2009
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7CHI
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![BU of 7chi by Molmil](/molmil-images/mine/7chi) | crystal structure of pco5 | Descriptor: | FE (III) ION, Plant cysteine oxidase 5 | Authors: | Guo, Q, Xu, C, Liao, S. | Deposit date: | 2020-07-05 | Release date: | 2020-11-25 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. J.Struct.Biol., 213, 2021
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7CXZ
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![BU of 7cxz by Molmil](/molmil-images/mine/7cxz) | crystal structure of pco2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, NICKEL (II) ION, ... | Authors: | Guo, Q, Xu, C, Liao, S, Chen, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. J.Struct.Biol., 213, 2021
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8GQE
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![BU of 8gqe by Molmil](/molmil-images/mine/8gqe) | Crystal structure of the W285A mutant of UVR8 in complex with RUP2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ultraviolet-B receptor UVR8, WD repeat-containing protein RUP2 | Authors: | Wang, Y.D, Wang, L.X, Guan, Z.Y, chang, H.F, Yin, P. | Deposit date: | 2022-08-30 | Release date: | 2022-09-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | RUP2 facilitates UVR8 redimerization via two interfaces. Plant Commun., 4, 2023
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7CHJ
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![BU of 7chj by Molmil](/molmil-images/mine/7chj) | crystal structure of pco4 | Descriptor: | CITRIC ACID, FE (III) ION, Plant cysteine oxidase 4 | Authors: | Guo, Q, Xu, C, Liao, S. | Deposit date: | 2020-07-05 | Release date: | 2020-11-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana. J.Struct.Biol., 213, 2021
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4KQA
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![BU of 4kqa by Molmil](/molmil-images/mine/4kqa) | Crystal structure of the golgi casein kinase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, Protein H03A11.1, ... | Authors: | Xiao, J. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Crystal structure of the Golgi casein kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KQB
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![BU of 4kqb by Molmil](/molmil-images/mine/4kqb) | crystal structure of the Golgi casein kinase with Mn/ADP bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Xiao, J. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.045 Å) | Cite: | Crystal structure of the Golgi casein kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
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7XC2
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![BU of 7xc2 by Molmil](/molmil-images/mine/7xc2) | Cryo EM structure of oligomeric complex formed by wheat CNL Sr35 and the effector AvrSr35 of the wheat stem rust pathogen | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Avirulence factor, CNL9 | Authors: | Alexander, F, Li, E.T, Aaron, L, Deng, Y.N, Sun, Y, Chai, J.J. | Deposit date: | 2022-03-22 | Release date: | 2022-09-21 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A wheat resistosome defines common principles of immune receptor channels. Nature, 610, 2022
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7DP8
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![BU of 7dp8 by Molmil](/molmil-images/mine/7dp8) | Crystal structure of T2R-TTL-Cevipabulin-eribulin complex | Descriptor: | (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.1~3,32~.1~3,33~.1~6,9~.1~12,16~.0~18,22~.0~29,36~.0~31,35~]hentetracontan-24-one (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, ... | Authors: | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | Deposit date: | 2020-12-18 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.446 Å) | Cite: | Cevipabulin-tubulin complex reveals a novel agent binding site on alpha-tubulin with tubulin degradation effect. Sci Adv, 7, 2021
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3U46
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![BU of 3u46 by Molmil](/molmil-images/mine/3u46) | CH04H/CH02L P212121 | Descriptor: | CH02 Light chain Fab, CH04 Heavy chain Fab | Authors: | Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2011-10-07 | Release date: | 2011-11-30 | Last modified: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.906 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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5FXS
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![BU of 5fxs by Molmil](/molmil-images/mine/5fxs) | IGFR-1R complex with a pyrimidine inhibitor. | Descriptor: | 2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide, ACETATE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | Authors: | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | Deposit date: | 2016-03-02 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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5FXR
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![BU of 5fxr by Molmil](/molmil-images/mine/5fxr) | IGFR-1R complex with a pyrimidine inhibitor. | Descriptor: | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-N-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | Authors: | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | Deposit date: | 2016-03-02 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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5FXQ
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![BU of 5fxq by Molmil](/molmil-images/mine/5fxq) | IGFR-1R complex with a pyrimidine inhibitor. | Descriptor: | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-N-(5-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | Authors: | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | Deposit date: | 2016-03-02 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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7K45
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7K43
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![BU of 7k43 by Molmil](/molmil-images/mine/7k43) | |
5IW4
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![BU of 5iw4 by Molmil](/molmil-images/mine/5iw4) | |