4N1L
Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions
Summary for 4N1L
| Entry DOI | 10.2210/pdb4n1l/pdb |
| Related | 4N1J 4N1K |
| Descriptor | NACHT, LRR and PYD domains-containing protein 14 (2 entities in total) |
| Functional Keywords | death domain fold, pyrin domain, nod-like receptor, signaling protein, protein binding, spermatogenesis, innate immunity |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 12309.03 |
| Authors | Eibl, C.,Hessenberger, M.,Wenger, J.,Brandstetter, H. (deposition date: 2013-10-04, release date: 2014-07-16, Last modification date: 2024-02-28) |
| Primary citation | Eibl, C.,Hessenberger, M.,Wenger, J.,Brandstetter, H. Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70:2007-2018, 2014 Cited by PubMed: 25004977DOI: 10.1107/S1399004714010311 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.986 Å) |
Structure validation
Download full validation report
