7YVO
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027/132 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH132 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVH
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH132 Fab | Descriptor: | Spike glycoprotein, TH132 Fab heavy chain, TH132 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVM
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH281 Fab heavy chain, TH281 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVF
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab | Descriptor: | Spike glycoprotein, TH027 Fab heavy chain, TH027 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVJ
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH236 Fab | Descriptor: | Spike glycoprotein, TH236 Fab heavy chain, TH236 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVE
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH027 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVL
| Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH272 Fab | Descriptor: | Spike glycoprotein, TH272 Fab heavy chain, TH272 Fab light chain | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7YVI
| Omicron BA.4/5 SARS-CoV-2 S in complex with TH236 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH236 Fab heavy chain, ... | Authors: | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | Deposit date: | 2022-08-19 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection. Nat Commun, 14, 2023
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7VT0
| Dimer structure of SORLA | Descriptor: | Sortilin-related receptor | Authors: | Xi, Z, Cang, W, Chuang, L. | Deposit date: | 2021-10-27 | Release date: | 2022-11-02 | Last modified: | 2023-05-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures reveal distinct apo conformations of sortilin-related receptor SORLA. Biochem.Biophys.Res.Commun., 600, 2022
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7XBB
| Crystal structure of PDE4D catalytic domain complexed with compound 23a | Descriptor: | (2~{R},4~{S})-6-ethyl-2-[(2~{E})-2-hydroxyiminoethyl]-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one, Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D, MAGNESIUM ION, ... | Authors: | Huang, Y.-Y, Luo, H.-B. | Deposit date: | 2022-03-21 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.100009 Å) | Cite: | Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects. Biochem Pharmacol, 202, 2022
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7XW9
| Cryo-EM structure of the TRH-bound human TRHR-Gq complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | Ji, S, Dong, Y, Chen, L, Zang, S, Shen, D, Guo, J, Qin, J, Zhang, H, Wang, W, Shen, Q, Mao, C, Zhang, Y. | Deposit date: | 2022-05-26 | Release date: | 2022-12-28 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis for the activation of thyrotropin-releasing hormone receptor. Cell Discov, 8, 2022
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7XZ4
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2IZV
| CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Debreczeni, J.E, Bullock, A, Papagrigoriou, E, Turnbull, A, Pike, A.C.W, Gorrec, F, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Knapp, S. | Deposit date: | 2006-07-26 | Release date: | 2006-08-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. Structure, 15, 2007
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2NMB
| DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES. | Descriptor: | PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN) | Authors: | Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D. | Deposit date: | 1998-10-29 | Release date: | 1998-11-04 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity. Nat.Struct.Biol., 5, 1998
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