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5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CSG
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BU of 5csg by Molmil
The crystal structure of beta2-microglobulin R97Q mutant
Descriptor: ACETATE ION, Beta-2-microglobulin
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CSB
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BU of 5csb by Molmil
The crystal structure of beta2-microglobulin D76N mutant at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.719 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CS7
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BU of 5cs7 by Molmil
The crystal structure of wt beta2-microglobulin at room temperature
Descriptor: Beta-2-microglobulin
Authors:de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMW
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BU of 4rmw by Molmil
Crystal structure of the D76A Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMU
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BU of 4rmu by Molmil
Crystal structure of the D76E Beta-2 Microglobulin mutant
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMV
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BU of 4rmv by Molmil
Crystal structure of the D76H Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMS
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BU of 4rms by Molmil
Crystal structure of the D53N Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMT
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BU of 4rmt by Molmil
Crystal structure of the D98N Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMR
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BU of 4rmr by Molmil
Crystal structure of the D38N Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMQ
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BU of 4rmq by Molmil
Crystal structure of the D59N Beta-2 Microglobulin mutant
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.461 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4OJ3
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BU of 4oj3 by Molmil
The crystal structure of V84P mutant of S. solfataricus Acylphosphatase
Descriptor: Acylphosphatase, GLYCEROL, SULFATE ION
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-01-20
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
4OJG
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BU of 4ojg by Molmil
The crystal structure of V84D mutant of S. solfataricus acylphosphatase
Descriptor: Acylphosphatase, GLYCEROL, PHOSPHATE ION
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-01-21
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.377 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
4OJH
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BU of 4ojh by Molmil
The crystal structure of truncated, Y86E mutant of S. solfataricus acylphosphatase
Descriptor: Acylphosphatase, SULFATE ION
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-01-21
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
6QW3
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BU of 6qw3 by Molmil
Calcium-bound gelsolin domain 2
Descriptor: CALCIUM ION, Gelsolin
Authors:Scalone, E, Boni, F, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2019-03-05
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.
Biochem.Biophys.Res.Commun., 518, 2019
4HOB
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BU of 4hob by Molmil
The crystal structure of the Zalpha domain from Cyprinid Herpes virus 3
Descriptor: Putative uncharacterized protein, SULFATE ION
Authors:Tome, A.R, Kus, K, de Rosa, M, Paulo, L.M, Figueiredo, D, Athanasiadis, A.
Deposit date:2012-10-22
Release date:2013-09-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of a poxvirus-like zalpha domain from cyprinid herpesvirus 3
J.Virol., 87, 2013
4KA4
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BU of 4ka4 by Molmil
Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Z-DNA-binding protein 1
Authors:Athanasiadis, A, de Rosa, M, De Sanctis, D.
Deposit date:2013-04-22
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
To be Published
4LB6
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BU of 4lb6 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (tetragonal form)
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', Protein kinase containing Z-DNA binding domains
Authors:De Rosa, M, Zacarias, S, Athanasiadis, A.
Deposit date:2013-06-20
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
4LB5
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BU of 4lb5 by Molmil
Crystal structure of PKZ Zalpha in complex with ds(CG)6 (hexagonal form)
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', ACETATE ION, Protein kinase containing Z-DNA binding domains
Authors:De Rosa, M, Zacarias, S, Athanasiadis, A.
Deposit date:2013-06-20
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013
6H1F
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BU of 6h1f by Molmil
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
Descriptor: Gelsolin, THIOCYANATE ION, gelsolin nanobody, ...
Authors:Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2018-07-11
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
4C7U
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BU of 4c7u by Molmil
Crystal structure of manganese superoxide dismutase from Arabidopsis thaliana
Descriptor: MANGANESE (II) ION, SUPEROXIDE DISMUTASE [MN] 1, MITOCHONDRIAL
Authors:Marques, A, Santos, S.P, Rosa, M, Carrondo, M.A, Abreu, I.A, Romao, C.V, Frazao, C.
Deposit date:2013-09-25
Release date:2014-10-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Crystal Structure of the Arabidopsis Thaliana Manganese Superoxide Dismutase at 1.95 A Resolution
To be Published
5KK3
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BU of 5kk3 by Molmil
Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils
Descriptor: Beta-amyloid protein 42
Authors:Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G.
Deposit date:2016-06-20
Release date:2016-07-13
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils.
J.Am.Chem.Soc., 138, 2016
3TM6
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BU of 3tm6 by Molmil
Crystal structure of the beta-2 microglobulin DIMC50 disulphide-linked homodimer mutant
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION
Authors:Colombo, M, Ricagno, S, Bolognesi, M.
Deposit date:2011-08-31
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A recurrent D-strand association interface is observed in beta-2 microglobulin oligomers.
Febs J., 279, 2012
3TLR
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BU of 3tlr by Molmil
Crystal Structure of the tetrameric Beta-2 microglobulin DIMC20 mutant
Descriptor: Beta-2-microglobulin, CADMIUM ION, SODIUM ION
Authors:Colombo, M, Ricagno, S, Bolognesi, M.
Deposit date:2011-08-30
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A recurrent D-strand association interface is observed in beta-2 microglobulin oligomers.
Febs J., 279, 2012
6EXW
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BU of 6exw by Molmil
Crystal structure of cIAP1-BIR3 in complex with a covalently bound SM
Descriptor: (3~{S},6~{S},7~{R},9~{a}~{S})-6-[[(2~{S})-2-(methylamino)propanoyl]amino]-5-oxidanylidene-~{N}-(phenylmethyl)-7-[(propanoylamino)methyl]-3,6,7,8,9,9~{a}-hexahydropyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION
Authors:Corti, A, Cossu, F, Milani, M, Mastrangelo, E.
Deposit date:2017-11-10
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs.
FEBS J., 285, 2018

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