1JMS
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![BU of 1jms by Molmil](/molmil-images/mine/1jms) | Crystal Structure of the Catalytic Core of Murine Terminal Deoxynucleotidyl Transferase | Descriptor: | MAGNESIUM ION, SODIUM ION, TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE | Authors: | Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Sukumar, N, Jourdan, N, Rougeon, F, Papanicolaou, C. | Deposit date: | 2001-07-19 | Release date: | 2002-01-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. Embo J., 21, 2002
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2JNR
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![BU of 2jnr by Molmil](/molmil-images/mine/2jnr) | Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | Descriptor: | ENV polyprotein, VIR165 | Authors: | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | Deposit date: | 2007-02-01 | Release date: | 2007-05-08 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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7SEU
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![BU of 7seu by Molmil](/molmil-images/mine/7seu) | Crystal structure of E coli contaminant protein YncE co-purified with a plant protein | Descriptor: | PQQ-dependent catabolism-associated beta-propeller protein | Authors: | Chai, L, Zhu, P, Chai, J, Pang, C, Andi, B, McsWeeney, S, Shanklin, J, Liu, Q. | Deposit date: | 2021-10-01 | Release date: | 2022-04-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement Crystals, 11, 2021
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7SEV
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![BU of 7sev by Molmil](/molmil-images/mine/7sev) | Crystal structure of E coli contaminant protein YadF co-purified with a plant protein | Descriptor: | Carbonic anhydrase 2, POTASSIUM ION, ZINC ION | Authors: | Chai, L, Zhu, P, Chai, J, Pang, C, Andi, B, McsWeeney, S, Shanklin, J, Liu, Q. | Deposit date: | 2021-10-01 | Release date: | 2021-11-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement Crystals, 11, 2021
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3GHJ
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![BU of 3ghj by Molmil](/molmil-images/mine/3ghj) | Crystal structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4 | Descriptor: | Putative integron gene cassette protein | Authors: | Sureshan, V, Deshpande, C, Harrop, S.J, Kudritska, M, Koenig, J.E, Evdokimova, E, Kim, Y, Edwards, A.M, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-03-03 | Release date: | 2009-03-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.471 Å) | Cite: | Structure from the mobile metagenome of Halifax Harbour Sewage Outfall: Integron Cassette Protein HFX_CASS4 To be Published
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1KDH
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![BU of 1kdh by Molmil](/molmil-images/mine/1kdh) | Binary Complex of Murine Terminal Deoxynucleotidyl Transferase with a Primer Single Stranded DNA | Descriptor: | 5'-D(P*(BRU)P*(BRU)P*(BRU)P*(BRU))-3', MAGNESIUM ION, SODIUM ION, ... | Authors: | Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Jourdan, N, Sukumar, N, Rougeon, F, Papanicolaou, C. | Deposit date: | 2001-11-13 | Release date: | 2002-05-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. EMBO J., 21, 2002
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1KEJ
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![BU of 1kej by Molmil](/molmil-images/mine/1kej) | Crystal Structure of Murine Terminal Deoxynucleotidyl Transferase complexed with ddATP | Descriptor: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, COBALT (II) ION, SODIUM ION, ... | Authors: | Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Jourdan, N, Sukumar, N, Rougeon, F, Papanicolaou, C. | Deposit date: | 2001-11-16 | Release date: | 2002-05-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. EMBO J., 21, 2002
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4OHF
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![BU of 4ohf by Molmil](/molmil-images/mine/4ohf) | Crystal structure of cytosolic nucleotidase II (LPG0095) in complex with GMP from Legionella pneumophila, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR1 | Descriptor: | Cytosolic IMP-GMP specific 5'-nucleotidase, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Srinivisan, B, Forouhar, F, Shukla, A, Sampangi, C, Kulkarni, S, Abashidze, M, Seetharaman, J, Lew, S, Mao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.M, Tong, L, Balaram, H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2014-01-17 | Release date: | 2014-02-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. Febs J., 281, 2014
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8GHT
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![BU of 8ght by Molmil](/molmil-images/mine/8ght) | Cryo-electron microscopy structure of the zinc transporter from Bordetella bronchiseptica | Descriptor: | CADMIUM ION, PHOSPHATIDYLETHANOLAMINE, Putative membrane protein | Authors: | Liu, Q, Chai, J, Pang, C.X, Shanklin, J. | Deposit date: | 2023-03-12 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters. Nat Commun, 14, 2023
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5DWU
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![BU of 5dwu by Molmil](/molmil-images/mine/5dwu) | Beta common receptor in complex with a Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Fab - Heavy Chain, ... | Authors: | Dhagat, U, Parker, M.W. | Deposit date: | 2015-09-23 | Release date: | 2015-12-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.97 Å) | Cite: | CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors. Mabs, 8, 2016
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6JPF
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![BU of 6jpf by Molmil](/molmil-images/mine/6jpf) | |
8V4X
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![BU of 8v4x by Molmil](/molmil-images/mine/8v4x) | Structure of MALT1 in complex with an allosteric inhibitor | Descriptor: | Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea | Authors: | Judge, R.A, Pappano, W.N. | Deposit date: | 2023-11-29 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.486 Å) | Cite: | Inhibition of MALT1 and BCL2 induces synergistic anti-tumor activity in models of B cell lymphoma. Mol.Cancer Ther., 2024
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6X3I
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![BU of 6x3i by Molmil](/molmil-images/mine/6x3i) | NNAS Fc mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain, beta-D-mannopyranose | Authors: | Wei, R, Zhou, Y.F. | Deposit date: | 2020-05-21 | Release date: | 2020-09-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.268 Å) | Cite: | Engineered Fc-glycosylation switch to eliminate antibody effector function. Mabs, 12, 2020
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8WZB
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![BU of 8wzb by Molmil](/molmil-images/mine/8wzb) | RS head-neck monomer | Descriptor: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | Authors: | Meng, X, Cong, Y. | Deposit date: | 2023-11-01 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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8X2U
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![BU of 8x2u by Molmil](/molmil-images/mine/8x2u) | Radial spoke head-neck dimer | Descriptor: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | Authors: | Meng, X, Cong, Y. | Deposit date: | 2023-11-10 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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5Z9O
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![BU of 5z9o by Molmil](/molmil-images/mine/5z9o) | |
2LGS
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![BU of 2lgs by Molmil](/molmil-images/mine/2lgs) | FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | Descriptor: | GLUTAMIC ACID, GLUTAMINE SYNTHETASE, MANGANESE (II) ION | Authors: | Liaw, S.-H, Eisenberg, D. | Deposit date: | 1994-08-05 | Release date: | 1994-11-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine. Proc.Natl.Acad.Sci.USA, 90, 1993
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7SSM
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![BU of 7ssm by Molmil](/molmil-images/mine/7ssm) | Crystal structure of human STING R232 in complex with compound 11 | Descriptor: | 2-({[(8R)-pyrazolo[1,5-a]pyrimidine-3-carbonyl]amino}methyl)-1-benzofuran-7-carboxylic acid, Stimulator of interferon genes protein | Authors: | Sack, J.S, Critton, D.A. | Deposit date: | 2021-11-11 | Release date: | 2022-02-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization. J.Med.Chem., 65, 2022
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5Z1F
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![BU of 5z1f by Molmil](/molmil-images/mine/5z1f) | |
6JQ1
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![BU of 6jq1 by Molmil](/molmil-images/mine/6jq1) | Crystal Structure of DdrO from Deinococcus geothermalis | Descriptor: | LITHIUM ION, Transcriptional regulator, XRE family | Authors: | Lu, H, Hua, Y, Zhao, Y. | Deposit date: | 2019-03-28 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO. Nucleic Acids Res., 47, 2019
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5YMV
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![BU of 5ymv by Molmil](/molmil-images/mine/5ymv) | Crystal structure of 9-mer peptide from influenza virus in complex with BF2*1201 | Descriptor: | ALA-VAL-LYS-GLY-VAL-GLY-THR-MET-VAL, Beta-2-microglobulin, Class I histocompatibility antigen, ... | Authors: | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | Deposit date: | 2017-10-22 | Release date: | 2018-10-24 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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5YMW
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![BU of 5ymw by Molmil](/molmil-images/mine/5ymw) | Crystal structure of 8-mer peptide from Rous sarcoma virus in complex with BF2*1201 | Descriptor: | Beta-2-microglobulin, Class I histocompatibility antigen, F10 alpha chain, ... | Authors: | Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F. | Deposit date: | 2017-10-22 | Release date: | 2018-10-24 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I. J Immunol., 201, 2018
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7RED
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![BU of 7red by Molmil](/molmil-images/mine/7red) | Holo Hemophilin from A. baumannii | Descriptor: | Hemophilin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bateman, T.J, Shah, M, Moraes, T.F. | Deposit date: | 2021-07-12 | Release date: | 2021-11-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nat Commun, 12, 2021
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7RE4
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![BU of 7re4 by Molmil](/molmil-images/mine/7re4) | Apo Hemophilin from A. baumannii | Descriptor: | Hemophilin | Authors: | Bateman, T.J, Shah, M, Moraes, T.F. | Deposit date: | 2021-07-12 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nat Commun, 12, 2021
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7REA
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![BU of 7rea by Molmil](/molmil-images/mine/7rea) | Apo Hemophilin from A. baumannii | Descriptor: | Hemophilin | Authors: | Bateman, T.J, Shah, M, Moraes, T.F. | Deposit date: | 2021-07-12 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nat Commun, 12, 2021
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