8YFI
 
 | | TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCA-3') | | Descriptor: | Activating signal cointegrator 1, DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3') | | Authors: | Ding, J, Yang, H, Hu, C. | | Deposit date: | 2024-02-24 | | Release date: | 2024-06-26 | | Last modified: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
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8YEW
 | | TRIP4 ASCH domain in unliganded form | | Descriptor: | Activating signal cointegrator 1 | | Authors: | Ding, J, Yang, H, Hu, C. | | Deposit date: | 2024-02-23 | | Release date: | 2024-06-26 | | Last modified: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
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8YXX
 | | TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCG-3') | | Descriptor: | Activating signal cointegrator 1, DNA (5'-D(*CP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*G)-3') | | Authors: | Ding, J, Yang, H, Hu, C. | | Deposit date: | 2024-04-03 | | Release date: | 2024-06-26 | | Last modified: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
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8YXW
 | | TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCC-3') | | Descriptor: | Activating signal cointegrator 1, DNA (5'-D(*GP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*C)-3') | | Authors: | Ding, J, Yang, H, Hu, C. | | Deposit date: | 2024-04-03 | | Release date: | 2024-06-26 | | Last modified: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 32, 2024
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2MYP
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2MYT
 | | An arsenate reductase in the intermediate state | | Descriptor: | Glutaredoxin arsenate reductase | | Authors: | Jin, C, Yu, C, Hu, C, Hu, Y. | | Deposit date: | 2015-01-30 | | Release date: | 2015-08-05 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction.
J.Biol.Chem., 290, 2015
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2MYN
 | | An arsenate reductase in reduced state | | Descriptor: | Glutaredoxin arsenate reductase | | Authors: | Jin, C, Yu, C, Hu, C, Hu, Y. | | Deposit date: | 2015-01-30 | | Release date: | 2015-08-05 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction.
J.Biol.Chem., 290, 2015
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3M95
 | | Crystal structure of autophagy-related protein Atg8 from the silkworm Bombyx mori | | Descriptor: | Autophagy related protein Atg8 | | Authors: | Teng, Y.-B, Hu, C, Zhang, X, Jiang, Y.L, Hu, H.-X, Zhou, C.Z. | | Deposit date: | 2010-03-20 | | Release date: | 2010-07-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of autophagy-related protein Atg8 from the silkworm Bombyx mori
Acta Crystallogr.,Sect.F, 66, 2010
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2MYU
 | | An arsenate reductase in oxidized state | | Descriptor: | Glutaredoxin arsenate reductase | | Authors: | Jin, C, Hu, C, Hu, Y. | | Deposit date: | 2015-01-30 | | Release date: | 2015-08-05 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A Hybrid Mechanism for the Synechocystis Arsenate Reductase Revealed by Structural Snapshots during Arsenate Reduction.
J.Biol.Chem., 290, 2015
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7R21
 | | elongated Cascade complex from type I-A CRISPR-Cas system | | Descriptor: | Cas11a, Cas7a, CrRNA (62-MER), ... | | Authors: | Hu, C, Ni, D, Nam, K.H, Stahlberg, H, Terns, M, Ke, A. | | Deposit date: | 2022-02-04 | | Release date: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots for an atypic type I CRISPR-Cas system
To Be Published
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7R2K
 | | elongated Cascade complex from type I-A CRISPR-Cas system | | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | Authors: | Hu, C, Ni, D, Nam, K.H, Terns, M, Stahlberg, H, Ke, A. | | Deposit date: | 2022-02-04 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural snapshots for an atypic type I CRISPR-Cas system
To Be Published
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5YC2
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5YCA
 | | Crystal structure of inner membrane protein Bqt4 in complex with LEM2 | | Descriptor: | Lap-Emerin-Man domain protein 2, Ubiquitin-like protein SMT3,Bouquet formation protein 4 | | Authors: | Chen, Y, Hu, C. | | Deposit date: | 2017-09-07 | | Release date: | 2018-11-14 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast.
Nucleic Acids Res., 47, 2019
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6A6W
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7YEU
 | | Superfolder green fluorescent protein with phosphine unnatural amino acid P3BF | | Descriptor: | Superfolder green fluorescent protein | | Authors: | Hu, C, Duan, H.Z, Liu, X.H, Chen, Y.X, Wang, J.Y. | | Deposit date: | 2022-07-06 | | Release date: | 2023-07-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Genetically Encoded Phosphine Ligand for Metalloprotein Design.
J.Am.Chem.Soc., 144, 2022
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6M4Q
 | | Cytochrome P450 monooxygenase StvP2 substrate-free structure | | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | | Deposit date: | 2020-03-08 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.
Nat Commun, 11, 2020
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6M4P
 | | Cytochrome P450 monooxygenase StvP2 substrate-bound structure | | Descriptor: | 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | | Deposit date: | 2020-03-08 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.
Nat Commun, 11, 2020
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8CSZ
 | | IscB and wRNA bound to Target DNA | | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | | Authors: | Schuler, G.A, Hu, C, Ke, A. | | Deposit date: | 2022-05-13 | | Release date: | 2022-06-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Science, 376, 2022
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8CTL
 | | IscB and wRNA bound to Target DNA (locked state) | | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | | Authors: | Schuler, G.A, Hu, C, Ke, A. | | Deposit date: | 2022-05-16 | | Release date: | 2022-06-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Science, 376, 2022
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4QLA
 | | Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori | | Descriptor: | Juvenile hormone epoxide hydrolase, PENTAETHYLENE GLYCOL | | Authors: | Zhou, K, Jia, N, Hu, C, Jiang, Y.L, Yang, J.P, Chen, Y, Li, S, Zhou, C.Z. | | Deposit date: | 2014-06-11 | | Release date: | 2014-09-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori.
Proteins, 82, 2014
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7YBF
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7UTN
 | | IscB and wRNA bound to Target DNA | | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | | Authors: | Schuler, G.A, Hu, C, Ke, A. | | Deposit date: | 2022-04-27 | | Release date: | 2022-06-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9.
Science, 376, 2022
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7MID
 | | Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA | | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ... | | Authors: | Hu, C.Y, Ke, A.K. | | Deposit date: | 2021-04-16 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI4
 | | Symmetrical PAM-PAM prespacer bound Cas4/Cas1/Cas2 complex | | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (35-MER), ... | | Authors: | Hu, C.Y, Ke, A.K. | | Deposit date: | 2021-04-16 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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7MI5
 | | Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex | | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (26-MER), ... | | Authors: | Hu, C.Y, Ke, A.K. | | Deposit date: | 2021-04-16 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
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