3ULE
 
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3GOQ
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1EHW
 | | HUMAN NUCLEOSIDE DIPHOSPHATE KINASE 4 | | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | | Authors: | Milon, L, Meyer, P, Chiadmi, M, Munier, A, Johansson, M, Karlsson, A, Lascu, I, Capeau, J, Janin, J, Lacombe, M.-L. | | Deposit date: | 2000-02-23 | | Release date: | 2000-05-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase.
J.Biol.Chem., 275, 2000
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1AK1
 | | FERROCHELATASE FROM BACILLUS SUBTILIS | | Descriptor: | FERROCHELATASE | | Authors: | Al-Karadaghi, S, Hansson, M, Nikonov, S, Jonsson, B, Hederstedt, L. | | Deposit date: | 1997-05-28 | | Release date: | 1997-12-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis.
Structure, 5, 1997
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5A7U
 | | Single-particle cryo-EM of co-translational folded adr1 domain inside the E. coli ribosome exit tunnel. | | Descriptor: | REGULATORY PROTEIN ADR1, ZINC ION | | Authors: | Nilsson, O.B, Hedman, R, Marino, J, Wickles, S, Bischoff, L, Johansson, M, Muller-Lucks, A, Trovato, F, Puglisi, J.D, O'Brien, E, Beckmann, R, von Heijne, G. | | Deposit date: | 2015-07-10 | | Release date: | 2015-09-16 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cotranslational Protein Folding Inside the Ribosome Exit Tunnel.
Cell Rep., 12, 2015
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2X31
 | | Modelling of the complex between subunits BchI and BchD of magnesium chelatase based on single-particle cryo-EM reconstruction at 7.5 ang | | Descriptor: | MAGNESIUM-CHELATASE 38 KDA SUBUNIT, MAGNESIUM-CHELATASE 60 KDA SUBUNIT | | Authors: | Lunqvist, J, Elmlund, H, Peterson Wulff, R, Berglund, L, Elmlund, D, Emanuelsson, C, Hebert, H, Willows, R.D, Hansson, M, Lindahl, M, Al-Karadaghi, S. | | Deposit date: | 2010-01-19 | | Release date: | 2010-11-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | ATP-Induced Conformational Dynamics in the Aaa+ Motor Unit of Magnesium Chelatase.
Structure, 18, 2010
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1GJS
 | | Solution structure of the Albumin binding domain of Streptococcal Protein G | | Descriptor: | IMMUNOGLOBULIN G BINDING PROTEIN G | | Authors: | Johansson, M.U, Frick, I.M, Nilsson, H, Kraulis, P.J, Hober, S, Jonasson, P, Nygren, A.P, Uhlen, M, Bjorck, L, Drakenberg, T, Forsen, S, Wikstrom, M. | | Deposit date: | 2001-08-02 | | Release date: | 2001-08-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure, Specificity, and Mode of Interaction for Bacterial Albumin-Binding Modules
J.Biol.Chem., 277, 2002
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1GJT
 | | Solution structure of the Albumin binding domain of Streptococcal Protein G | | Descriptor: | IMMUNOGLOBULIN G BINDING PROTEIN G | | Authors: | Johansson, M.U, Frick, I.M, Nilsson, H, Kraulis, P.J, Hober, S, Jonasson, P, Nygren, A.P, Uhlen, M, Bjorck, L, Drakenberg, T, Forsen, S, Wikstrom, M. | | Deposit date: | 2001-08-02 | | Release date: | 2001-08-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure, Specificity, and Mode of Interaction for Bacterial Albumin-Binding Modules
J.Biol.Chem., 277, 2002
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4OQS
 | | Crystal structure of CYP105AS1 | | Descriptor: | CYP105AS1, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Leys, D. | | Deposit date: | 2014-02-10 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4OQR
 | | Structure of a CYP105AS1 mutant in complex with compactin | | Descriptor: | CYP105AS1, Mevastatin, Compactin, ... | | Authors: | Leys, D. | | Deposit date: | 2014-02-10 | | Release date: | 2015-02-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.
Proc.Natl.Acad.Sci.USA, 112, 2015
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7SUS
 | | Crystal structure of Apelin receptor in complex with small molecule | | Descriptor: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apelin receptor, ... | | Authors: | Xu, F, Yue, Y, Liu, L.E, Han, G.W, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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6LN2
 | | Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab7F38_heavy chain, Fab7F38_light chain, ... | | Authors: | Wu, F, Yang, L, Hang, K, Laursen, M, Wu, L, Han, G.W, Ren, Q, Roed, N.K, Lin, G, Hanson, M, Jiang, H, Wang, M, Reedtz-Runge, S, Song, G, Stevens, R.C. | | Deposit date: | 2019-12-28 | | Release date: | 2020-03-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Full-length human GLP-1 receptor structure without orthosteric ligands.
Nat Commun, 11, 2020
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5XF1
 | | Structure of the Full-length glucagon class B G protein-coupled receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | | Deposit date: | 2017-04-06 | | Release date: | 2017-05-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
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5XEZ
 | | Structure of the Full-length glucagon class B G protein-coupled receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, ... | | Authors: | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | | Deposit date: | 2017-04-06 | | Release date: | 2017-05-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
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7W0N
 | | Cryo-EM structure of a dimeric GPCR-Gi complex with peptide | | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, F, Yue, Y, Wu, L.J, Liu, L.E, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (4.21 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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7W0M
 | | Cryo-EM structure of a monomeric GPCR-Gi complex with small molecule | | Descriptor: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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7W0L
 | | Cryo-EM structure of a dimeric GPCR-Gi complex with small molecule | | Descriptor: | (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, Y, Liu, L.E, Wu, L.J, Xu, F, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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7W0O
 | | Cryo-EM structure of a monomeric GPCR-Gi complex with peptide | | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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7W0P
 | | Cryo-EM structure of a GPCR-Gi complex with peptide | | Descriptor: | Apelin receptor early endogenous ligand, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, F, Yue, Y, Liu, L.E, Wu, L.J, Hanson, M. | | Deposit date: | 2021-11-18 | | Release date: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural insight into apelin receptor-G protein stoichiometry.
Nat.Struct.Mol.Biol., 29, 2022
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2BSL
 | | Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,4-dihydroxybenzoate | | Descriptor: | 3,4-DIHYDROXYBENZOIC ACID, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE A, ... | | Authors: | Wolfe, A.E, Hansen, M, Gattis, S.G, Hu, Y.-C, Johansson, E, Arent, S, Larsen, S, Palfey, B.A. | | Deposit date: | 2005-05-23 | | Release date: | 2006-08-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Interaction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase from Lactococcus Lactis.
Biochemistry, 46, 2007
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2BX7
 | | Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,5-dihydroxybenzoate | | Descriptor: | 3,5-DIHYDROXYBENZOATE, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE, ... | | Authors: | Wolfe, A.E, Hansen, M, Gattis, S.G, Hu, Y.-C, Johansson, E, Arent, S, Larsen, S, Palfey, B.A. | | Deposit date: | 2005-07-25 | | Release date: | 2006-08-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Interaction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase from Lactococcus Lactis.
Biochemistry, 46, 2007
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7B1O
 | | Crystal structure of the indoleamine 2,3-dioxygenase 1 (IDO1) in complex with compound 22 | | Descriptor: | 4-chloranyl-N-[(1R)-1-[(1S,5R)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide, Indoleamine 2,3-dioxygenase 1 | | Authors: | Lammens, A, Krapp, S, Lewis, R.T, Hamilton, M.M. | | Deposit date: | 2020-11-25 | | Release date: | 2021-09-29 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.
J.Med.Chem., 64, 2021
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7KQL
 | | Anti-Tim3 antibody Fab complex | | Descriptor: | GLYCEROL, Hepatitis A virus cellular receptor 2, Tim3.18 Fab heavy chain, ... | | Authors: | Deng, X.A, West, S.M, Strop, P. | | Deposit date: | 2020-11-16 | | Release date: | 2022-02-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Tim-3 mediates T cell trogocytosis to limit antitumor immunity.
J.Clin.Invest., 132, 2022
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6KUK
 | | Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUR
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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