6W7Z
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![BU of 6w7z by Molmil](/molmil-images/mine/6w7z) | RNF12 RING domain in complex with Ube2d2 | Descriptor: | E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2020-03-19 | Release date: | 2020-05-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
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6W9A
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![BU of 6w9a by Molmil](/molmil-images/mine/6w9a) | RNF12 RING domain in complex with Ube2e2 | Descriptor: | E3 ubiquitin-protein ligase RLIM, GLYCEROL, Ubiquitin-conjugating enzyme E2 E2, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2020-03-22 | Release date: | 2020-05-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains. J.Mol.Biol., 432, 2020
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5ULK
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![BU of 5ulk by Molmil](/molmil-images/mine/5ulk) | |
2KUA
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![BU of 2kua by Molmil](/molmil-images/mine/2kua) | |
7MYF
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![BU of 7myf by Molmil](/molmil-images/mine/7myf) | Ubiquitin variant UbV.k.1 in complex with Ube2k | Descriptor: | Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K | Authors: | Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. | Deposit date: | 2021-05-21 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
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7MYH
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![BU of 7myh by Molmil](/molmil-images/mine/7myh) | Ubiquitin variant UbV.k.2 in complex with Ube2k | Descriptor: | GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K | Authors: | Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. | Deposit date: | 2021-05-21 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
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2JM6
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![BU of 2jm6 by Molmil](/molmil-images/mine/2jm6) | Solution structure of MCL-1 complexed with NOXAB | Descriptor: | Myeloid cell leukemia-1 protein Mcl-1 homolog, Noxa | Authors: | Czabotar, P.E, Lee, E.F, van Delft, M.F, Day, C.L, Smith, B.J, Huang, D.C.S, Fairlie, W.D, Hinds, M.G, Colman, P.M. | Deposit date: | 2006-10-17 | Release date: | 2007-03-20 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structural insights into the degradation of Mcl-1 induced by BH3 domains Proc.Natl.Acad.Sci.Usa, 104, 2007
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2KMF
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![BU of 2kmf by Molmil](/molmil-images/mine/2kmf) | Solution Structure of Psb27 from cyanobacterial photosystem II | Descriptor: | Photosystem II 11 kDa protein | Authors: | Mabbitt, P.D, Rautureau, G.J.P, Day, C.L, Wilbanks, S.M, Eaton-Rye, J.J, Hinds, M.G. | Deposit date: | 2009-07-28 | Release date: | 2009-09-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of Psb27 from cyanobacterial photosystem II Biochemistry, 48, 2009
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2VJF
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![BU of 2vjf by Molmil](/molmil-images/mine/2vjf) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | Descriptor: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2007-12-10 | Release date: | 2008-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans. Cell Death Differ., 15, 2008
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2VJE
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![BU of 2vje by Molmil](/molmil-images/mine/2vje) | Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | Descriptor: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2007-12-10 | Release date: | 2008-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ., 15, 2008
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5D0K
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![BU of 5d0k by Molmil](/molmil-images/mine/5d0k) | Structure of UbE2D2:RNF165:Ub complex | Descriptor: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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2VOI
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![BU of 2voi by Molmil](/molmil-images/mine/2voi) | Structure of mouse A1 bound to the Bid BH3-domain | Descriptor: | BCL-2-RELATED PROTEIN A1, BH3-INTERACTING DOMAIN DEATH AGONIST P13, CHLORIDE ION | Authors: | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | Deposit date: | 2008-02-17 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1. Structure, 16, 2008
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5D0I
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![BU of 5d0i by Molmil](/molmil-images/mine/5d0i) | Structure of RING finger protein 165 | Descriptor: | RING finger protein 165, SULFATE ION, ZINC ION | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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5D0M
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![BU of 5d0m by Molmil](/molmil-images/mine/5d0m) | Structure of UbE2D2:RNF165:Ub complex | Descriptor: | PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ... | Authors: | Wright, J.D, Day, C.L, Mace, P.D. | Deposit date: | 2015-08-03 | Release date: | 2015-12-09 | Last modified: | 2016-01-20 | Method: | X-RAY DIFFRACTION (1.913 Å) | Cite: | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
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2VOF
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![BU of 2vof by Molmil](/molmil-images/mine/2vof) | Structure of mouse A1 bound to the Puma BH3-domain | Descriptor: | BCL-2-BINDING COMPONENT 3, BCL-2-RELATED PROTEIN A1, CHLORIDE ION | Authors: | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | Deposit date: | 2008-02-17 | Release date: | 2008-03-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1. Structure, 16, 2008
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2VOG
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![BU of 2vog by Molmil](/molmil-images/mine/2vog) | Structure of mouse A1 bound to the Bmf BH3-domain | Descriptor: | BCL-2-MODIFYING FACTOR, BCL-2-RELATED PROTEIN A1, CHLORIDE ION | Authors: | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | Deposit date: | 2008-02-17 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1. Structure, 16, 2008
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5DFL
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![BU of 5dfl by Molmil](/molmil-images/mine/5dfl) | |
2VOH
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![BU of 2voh by Molmil](/molmil-images/mine/2voh) | Structure of mouse A1 bound to the Bak BH3-domain | Descriptor: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, BCL-2-RELATED PROTEIN A1, CITRIC ACID, ... | Authors: | Smits, C, Czabotar, P.E, Hinds, M.G, Day, C.L. | Deposit date: | 2008-02-17 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1. Structure, 16, 2008
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3EB5
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![BU of 3eb5 by Molmil](/molmil-images/mine/3eb5) | Structure of the cIAP2 RING domain | Descriptor: | Baculoviral IAP repeat-containing protein 3, SODIUM ION, ZINC ION | Authors: | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | Deposit date: | 2008-08-27 | Release date: | 2008-09-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment. J.Biol.Chem., 283, 2008
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3EB6
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![BU of 3eb6 by Molmil](/molmil-images/mine/3eb6) | Structure of the cIAP2 RING domain bound to UbcH5b | Descriptor: | Baculoviral IAP repeat-containing protein 3, Ubiquitin-conjugating enzyme E2 D2, ZINC ION | Authors: | Mace, P.D, Linke, K, Schumacher, F.-R, Smith, C.A, Day, C.L. | Deposit date: | 2008-08-27 | Release date: | 2008-09-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment. J.Biol.Chem., 283, 2008
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6CGA
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![BU of 6cga by Molmil](/molmil-images/mine/6cga) | Structure of the PR-DUB complex | Descriptor: | Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso | Authors: | Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D. | Deposit date: | 2018-02-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes. Nat Commun, 9, 2018
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7L3L
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![BU of 7l3l by Molmil](/molmil-images/mine/7l3l) | Structure of TRAF5 and TRAF6 RING Hetero dimer | Descriptor: | TNF receptor-associated factor 5, TNF receptor-associated factor 6, ZINC ION | Authors: | Das, A, Middleton, A.J, Padala, P, Day, C.L. | Deposit date: | 2020-12-17 | Release date: | 2021-02-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structure and ubiquitin binding properties of TRAF RING heterodimers. J.Mol.Biol., 2021
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1O0L
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![BU of 1o0l by Molmil](/molmil-images/mine/1o0l) | THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY | Descriptor: | Apoptosis regulator Bcl-W | Authors: | Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L. | Deposit date: | 2003-02-22 | Release date: | 2003-04-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity Embo J., 22, 2003
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4NWZ
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![BU of 4nwz by Molmil](/molmil-images/mine/4nwz) | Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum at 2.5A resolution | Descriptor: | FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Nakatani, Y, Heikal, A, Lott, J.S, Sazanov, L.A, Baker, E.N, Cook, G.M. | Deposit date: | 2013-12-07 | Release date: | 2014-02-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation. Mol.Microbiol., 91, 2014
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1DSN
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![BU of 1dsn by Molmil](/molmil-images/mine/1dsn) | D60S N-TERMINAL LOBE HUMAN LACTOFERRIN | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Faber, H.R, Norris, G.E, Baker, E.N. | Deposit date: | 1995-12-13 | Release date: | 1996-03-08 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Altered domain closure and iron binding in transferrins: the crystal structure of the Asp60Ser mutant of the amino-terminal half-molecule of human lactoferrin. J.Mol.Biol., 256, 1996
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