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6LNT
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BU of 6lnt by Molmil
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Descriptor: Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ...
Authors:Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M.
Deposit date:2020-01-02
Release date:2020-02-26
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
7JX3
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BU of 7jx3 by Molmil
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab domain of monoclonal antibody S2H14, Heavy chain of Fab domain of monoclonal antibody S304, ...
Authors:Snell, G, Czudnochowski, N, Rosen, L.E, Nix, J.C, Corti, D, Veesler, D, Park, Y.J, Walls, A.C, Tortorici, M.A, Cameroni, E, Pinto, D, Beltramello, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-08-26
Release date:2020-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell, 183, 2020
7L0N
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BU of 7l0n by Molmil
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Snell, G, Czudnochowski, N, Dillen, J, Nix, J.C, Croll, T.I, Corti, D.
Deposit date:2020-12-11
Release date:2021-02-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.
Cell, 184, 2021
3ZTJ
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BU of 3ztj by Molmil
Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:Voss, J.E, Vachieri, S.G, Gamblin, S.J, Collins, P.J, Haire, L.F, Skehel, J.J.
Deposit date:2011-07-08
Release date:2011-08-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
5JW5
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BU of 5jw5 by Molmil
Structure of MEDI8852 Fab Fragment
Descriptor: MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
Authors:Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW3
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BU of 5jw3 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H7 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW4
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BU of 5jw4 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H5 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
6TOU
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BU of 6tou by Molmil
Rabies virus glycoprotein PH domain in complex with the scFv fragment of broadly neutralizing human antibody RVC20
Descriptor: CALCIUM ION, CHLORIDE ION, Glycoprotein,Glycoprotein, ...
Authors:Hellert, J, Rey, F.A.
Deposit date:2019-12-12
Release date:2020-02-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.587 Å)
Cite:Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.
Nat Commun, 11, 2020
9AU2
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BU of 9au2 by Molmil
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Tortorici, M.A, Park, Y.J, Veelser, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-28
Release date:2024-10-16
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification.
Cell, 187, 2024
6HJR
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BU of 6hjr by Molmil
Structure of full-length Influenza Hemagglutinin with tilted transmembrane (A/duck/Alberta/35/76[H1N1])
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
9ASD
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BU of 9asd by Molmil
VIR-7229 Fab fragment bound the SARS-CoV-2 BA.2.86 spike trimer (local refinement of the BA 2.86 RBD/VIR-7229 VHVL)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VIR-7229 Fab heavy chain, ...
Authors:Park, Y.J, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2024-02-25
Release date:2024-10-16
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification.
Cell, 187, 2024
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
Authors:Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RWY
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BU of 4rwy by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Acharya, P, Luongo, T.S, Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
5Y0A
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BU of 5y0a by Molmil
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Descriptor: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
Authors:Wang, J.Q, Lok, S.M.
Deposit date:2017-07-15
Release date:2017-10-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (22 Å)
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
8DYA
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BU of 8dya by Molmil
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-08-03
Release date:2022-11-30
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
Sci Immunol, 7, 2022
5OMZ
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BU of 5omz by Molmil
Solution structure of domain III (DIII)of Zika virus Envelope protein
Descriptor: Envelope Protein
Authors:Zerbe, O, Bardelli, M.
Deposit date:2017-08-02
Release date:2017-10-04
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
8ERR
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BU of 8err by Molmil
SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8ERQ
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BU of 8erq by Molmil
SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8DF5
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BU of 8df5 by Molmil
SARS-CoV-2 Beta RBD in complex with human ACE2 and S304 Fab and S309 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D.
Deposit date:2022-06-21
Release date:2022-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution.
Science, 377, 2022
9B2C
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BU of 9b2c by Molmil
Structure of the Porcine deltacoronavirus (PDCoV) receptor-binding domain bound to the PD33 antibody Fab fragment and the Kappa light chain nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kappa light chain nanobody, PD33 Fab heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2024-03-14
Release date:2024-11-13
Last modified:2024-12-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses.
Immunity, 57, 2024
8S9G
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BU of 8s9g by Molmil
SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-03-28
Release date:2023-10-04
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
7OH1
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BU of 7oh1 by Molmil
Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Descriptor: FAB TT110, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021

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