3LR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lr2 by Molmil](/molmil-images/mine/3lr2) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1 | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Johansson, J, Knight, S.D, Rising, A, Casals, C, Saenz, A. | Deposit date: | 2010-02-10 | Release date: | 2010-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
|
|
3LR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lr6 by Molmil](/molmil-images/mine/3lr6) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | Descriptor: | Major ampullate spidroin 1, TRIETHYLENE GLYCOL | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Saenz, A, Casals, C, Rising, A, Johansson, J, Knight, S.D. | Deposit date: | 2010-02-10 | Release date: | 2010-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
|
|
3LR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lr8 by Molmil](/molmil-images/mine/3lr8) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1, ... | Authors: | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D. | Deposit date: | 2010-02-10 | Release date: | 2010-05-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
|
|
5LEJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lej by Molmil](/molmil-images/mine/5lej) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | Descriptor: | DNA (30-MER), Listeriolysin regulatory protein | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-06-29 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
5LRS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lrs by Molmil](/molmil-images/mine/5lrs) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30-bp operator PrfA-box motif | Descriptor: | DNA (30-MER), GLUTATHIONE, Listeriolysin positive regulatory factor A | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-08-19 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
5NDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nda by Molmil](/molmil-images/mine/5nda) | NMR Structural Characterisation of Pharmaceutically Relevant Proteins Obtained Through a Novel Recombinant Production: The Case of The Pulmonary Surfactant Polypeptide C Analogue rSP-C33Leu. | Descriptor: | rSP-C33Leu -RECOMBINANT PULMONARY SURFACTANT-ASSOCIATED POLYPEPTIDE C ANALOGUE- | Authors: | Venturi, L, Pioselli, B, Johansson, J, Rising, A, Kronqvist, N, Nordling, K. | Deposit date: | 2017-03-08 | Release date: | 2017-06-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Efficient protein production inspired by how spiders make silk. Nat Commun, 8, 2017
|
|
5LEK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lek by Molmil](/molmil-images/mine/5lek) | The Transcriptional Regulator PrfA-G145S mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | Descriptor: | DNA (30-MER), Listeriolysin regulatory protein | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-06-29 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
5LRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lrr by Molmil](/molmil-images/mine/5lrr) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione | Descriptor: | GLUTATHIONE, HYDROGENPHOSPHATE ION, Listeriolysin positive regulatory factor A, ... | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-08-19 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.171 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
2MX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mx9 by Molmil](/molmil-images/mine/2mx9) | NMR structure of N-terminal domain from A. ventricosus minor ampullate spidroin (MiSp) at pH 5.5 | Descriptor: | Minor ampullate spidroin | Authors: | Otikovs, M, Jaudzems, K, Chen, G, Nordling, K, Rising, A, Johansson, J. | Deposit date: | 2014-12-17 | Release date: | 2015-08-19 | Method: | SOLUTION NMR | Cite: | Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains. Chembiochem, 16, 2015
|
|
2MX8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mx8 by Molmil](/molmil-images/mine/2mx8) | NMR structure of N-terminal domain from A. ventricosus minor ampullate spidroin (MiSp) at pH 7.2 | Descriptor: | Minor ampullate spidroin | Authors: | Otikovs, M, Jaudzems, K, Chen, G, Nordling, K, Rising, A, Johansson, J. | Deposit date: | 2014-12-17 | Release date: | 2015-08-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains. Chembiochem, 16, 2015
|
|
2BFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bfi by Molmil](/molmil-images/mine/2bfi) | Molecular basis for amyloid fibril formation and stability | Descriptor: | SYNTHETIC PEPTIDE | Authors: | Makin, O.S, Atkins, E, Sikorski, P, Johansson, J, Serpell, L.C. | Deposit date: | 2004-12-07 | Release date: | 2005-01-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Molecular Basis for Amyloid Fibril Formation and Stability Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
2LTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lth by Molmil](/molmil-images/mine/2lth) | NMR structure of major ampullate spidroin 1 N-terminal domain at pH 5.5 | Descriptor: | Major ampullate spidroin 1 | Authors: | Otikovs, M, Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S, Johansson, J. | Deposit date: | 2012-05-25 | Release date: | 2013-11-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation. Nat Commun, 5, 2014
|
|
2LPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lpi by Molmil](/molmil-images/mine/2lpi) | NMR structure of a monomeric mutant (A72R) of major ampullate spidroin 1 N-terminal domain | Descriptor: | Major ampullate spidroin 1 | Authors: | Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S.D, Johansson, J. | Deposit date: | 2012-02-14 | Release date: | 2012-06-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain. J.Mol.Biol., 422, 2012
|
|
5F1R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5f1r by Molmil](/molmil-images/mine/5f1r) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (C10) | Descriptor: | (3~{R})-8-cyclopropyl-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, Listeriolysin regulatory protein | Authors: | Begum, A, Grundstrom, C, Good, J.A.D, Andersson, C, ALmqvist, F, Johansson, J, Sauer, U.H, Sauer-Eriksson, A.E. | Deposit date: | 2015-11-30 | Release date: | 2016-03-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA. Cell Chem Biol, 23, 2016
|
|
7OOM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oom by Molmil](/molmil-images/mine/7oom) | |
1QND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qnd by Molmil](/molmil-images/mine/1qnd) | STEROL CARRIER PROTEIN-2, NMR, 20 STRUCTURES | Descriptor: | NONSPECIFIC LIPID-TRANSFER PROTEIN | Authors: | Lopez-Garcia, F, Szyperski, T, Dyer, J.H, Choinowski, T, Seedorf, U, Hauser, H, Wuthrich, K. | Deposit date: | 1999-10-14 | Release date: | 2000-07-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of the Sterol Carrier Protein-2: Implications for the Biological Role J.Mol.Biol., 295, 2000
|
|
6T5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t5i by Molmil](/molmil-images/mine/6t5i) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with inhibitor of WNT production (IWP)-2 | Descriptor: | DIMETHYL SULFOXIDE, Listeriolysin positive regulatory factor A, SODIUM ION, ... | Authors: | Oelker, M, Grundstrom, C, Blumenthal, A, Sauer-Eriksson, A.E. | Deposit date: | 2019-10-16 | Release date: | 2021-10-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. Plos Pathog., 18, 2022
|
|
6TV5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tv5 by Molmil](/molmil-images/mine/6tv5) | |
8CJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cj7 by Molmil](/molmil-images/mine/8cj7) | HDAC6 selective degraded (difluoromethyl)-1,3,4-oxadiazole substrate inhibitor | Descriptor: | 6-[(5-pyridin-2-yl-1,2$l^{4},3,4-tetrazacyclopenta-1,3-dien-2-yl)methyl]pyridine-3-carbohydrazide, Histone deacetylase 6, IODIDE ION, ... | Authors: | Sandmark, J, Ek, M, Ripa, L. | Deposit date: | 2023-02-12 | Release date: | 2023-10-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism. J.Med.Chem., 66, 2023
|
|
8AS5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8as5 by Molmil](/molmil-images/mine/8as5) | |
8A5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a5i by Molmil](/molmil-images/mine/8a5i) | Cryo-EM structure of Lincomycin bound to the Listeria monocytogenes 50S ribosomal subunit. | Descriptor: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2022-06-15 | Release date: | 2022-11-02 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8A63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a63 by Molmil](/molmil-images/mine/8a63) | Cryo-EM structure of Listeria monocytogenes 50S ribosomal subunit. | Descriptor: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ... | Authors: | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2022-06-16 | Release date: | 2022-11-02 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8A57
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a57 by Molmil](/molmil-images/mine/8a57) | Cryo-EM structure of HflXr bound to the Listeria monocytogenes 50S ribosomal subunit. | Descriptor: | 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L11, ... | Authors: | Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2022-06-14 | Release date: | 2022-11-02 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res., 50, 2022
|
|
8C7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7u by Molmil](/molmil-images/mine/8c7u) | |
8C7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7o by Molmil](/molmil-images/mine/8c7o) | |