8C7S

Transcriptional pleiotropic repressor CodY from Staphylococcus aureus in complex with Ile, GTP, and a 30-bp DNA fragment encompassing two overlapping binding sites

Summary for 8C7S

Entry DOI	10.2210/pdb8c7s/pdb
Descriptor	DNA (30-MER), Global transcriptional regulator CodY (Fragment), GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
Functional Keywords	gtp sensing, pleiotropic transcription regulator, gtp, dna complex, transcription
Biological source	Staphylococcus aureus (strain USA300) More
Total number of polymer chains	4
Total formula weight	77368.84
Authors	Hainzl, T.,Sauer-Eriksson, A.E. (deposition date: 2023-01-17, release date: 2023-07-19, Last modification date: 2023-11-15)
Primary citation	Hainzl, T.,Bonde, M.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E. Structural insights into CodY activation and DNA recognition. Nucleic Acids Res., 51:7631-7648, 2023 Cited by PubMed: 37326020 DOI: 10.1093/nar/gkad512 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation