7DFW
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![BU of 7dfw by Molmil](/molmil-images/mine/7dfw) | Cryo_EM structure of delta N-NPC1L1-CLR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, M, Sun, S. | Deposit date: | 2020-11-10 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. Sci Adv, 7, 2021
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7DFZ
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![BU of 7dfz by Molmil](/molmil-images/mine/7dfz) | Cryo_EM structure of delta N-NPC1L1-EZE | Descriptor: | (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, M, Sun, S. | Deposit date: | 2020-11-10 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. Sci Adv, 7, 2021
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7DJJ
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![BU of 7djj by Molmil](/molmil-images/mine/7djj) | Structure of four truncated and mutated forms of quenching protein lumenal domains | Descriptor: | Protein SUPPRESSOR OF QUENCHING 1, chloroplastic, SODIUM ION, ... | Authors: | Yu, G.M, Pan, X.W, Li, M. | Deposit date: | 2020-11-20 | Release date: | 2022-06-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.69806433 Å) | Cite: | Structure of Arabidopsis SOQ1 lumenal region unveils C-terminal domain essential for negative regulation of photoprotective qH. Nat.Plants, 8, 2022
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7DJM
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![BU of 7djm by Molmil](/molmil-images/mine/7djm) | Structure of four truncated and mutated forms of quenching protein | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Protein SUPPRESSOR OF QUENCHING 1, ... | Authors: | Yu, G.M, Pan, X.W, Li, M. | Deposit date: | 2020-11-20 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.70000112 Å) | Cite: | Structure of Arabidopsis SOQ1 lumenal region unveils C-terminal domain essential for negative regulation of photoprotective qH. Nat.Plants, 8, 2022
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7DJK
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![BU of 7djk by Molmil](/molmil-images/mine/7djk) | Structure of four truncated and mutated forms of quenching protein | Descriptor: | CHLORIDE ION, Protein SUPPRESSOR OF QUENCHING 1, chloroplastic, ... | Authors: | Yu, G.M, Pan, X.W, Li, M. | Deposit date: | 2020-11-20 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.80145121 Å) | Cite: | Structure of Arabidopsis SOQ1 lumenal region unveils C-terminal domain essential for negative regulation of photoprotective qH. Nat.Plants, 8, 2022
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7DJL
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![BU of 7djl by Molmil](/molmil-images/mine/7djl) | Structure of four truncated and mutated forms of quenching protein | Descriptor: | CHLORIDE ION, Protein SUPPRESSOR OF QUENCHING 1, chloroplastic, ... | Authors: | Yu, G.M, Pan, X.W, Li, M. | Deposit date: | 2020-11-20 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.96077824 Å) | Cite: | Structure of Arabidopsis SOQ1 lumenal region unveils C-terminal domain essential for negative regulation of photoprotective qH. Nat.Plants, 8, 2022
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7E5W
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![BU of 7e5w by Molmil](/molmil-images/mine/7e5w) | The structure of CcpA from Staphylococcus aureus | Descriptor: | Catabolite control protein A, SULFATE ION | Authors: | Yu, G, Wei, X. | Deposit date: | 2021-02-20 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation. J.Biol.Chem., 298, 2022
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7YPX
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![BU of 7ypx by Molmil](/molmil-images/mine/7ypx) | Cyanophage Pam3 fiber | Descriptor: | Pam3 tail fiber proreins, tail fiber chaperone | Authors: | Wei, Z.L, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2022-08-04 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural Insights into the Chaperone-Assisted Assembly of a Simplified Tail Fiber of the Myocyanophage Pam3. Viruses, 14, 2022
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7YQK
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![BU of 7yqk by Molmil](/molmil-images/mine/7yqk) | cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1 | Descriptor: | DNA (145-MER), Histone H2AX, Histone H2B, ... | Authors: | Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L. | Deposit date: | 2022-08-07 | Release date: | 2022-08-17 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. J.Am.Chem.Soc., 144, 2022
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7EEA
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![BU of 7eea by Molmil](/molmil-images/mine/7eea) | |
7EEQ
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![BU of 7eeq by Molmil](/molmil-images/mine/7eeq) | Cyanophage Pam1 tail machine | Descriptor: | Needle head proteins, Tailspike head-binding domain | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2021-03-19 | Release date: | 2021-10-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1. Structure, 30, 2022
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7EEP
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![BU of 7eep by Molmil](/molmil-images/mine/7eep) | Cyanophage Pam1 portal-adaptor complex | Descriptor: | Pam1 adaptor proteins, Pam1 portal proteins | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2021-03-19 | Release date: | 2021-10-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1. Structure, 30, 2022
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7EEL
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![BU of 7eel by Molmil](/molmil-images/mine/7eel) | Cyanophage Pam1 capsid asymmetric unit | Descriptor: | Cement (decoration) proteins, Major capsid proteins | Authors: | Zhang, J.T, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2021-03-19 | Release date: | 2021-10-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1. Structure, 30, 2022
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7WCT
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![BU of 7wct by Molmil](/molmil-images/mine/7wct) | Crystal structure of FGFR4 kinase domain with 7v | Descriptor: | Fibroblast growth factor receptor 4, GLYCEROL, SULFATE ION, ... | Authors: | Chen, X.J, Lin, Q.M, Dai, S.Y, Chen, Y.H. | Deposit date: | 2021-12-20 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.106 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives as Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4. J.Med.Chem., 65, 2022
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7WCW
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![BU of 7wcw by Molmil](/molmil-images/mine/7wcw) | Crystal structure of FGFR4(V550L) kinase domain with 7v | Descriptor: | Fibroblast growth factor receptor 4, SULFATE ION, ~{N}-[2-[[5-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1~{H}-indazol-3-yl]amino]-3-fluoranyl-5-(4-morpholin-4-ylpiperidin-1-yl)phenyl]propanamide | Authors: | Chen, X.J, Lin, Q.M, Dai, S.Y, Chen, Y.H. | Deposit date: | 2021-12-20 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.317 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives as Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4. J.Med.Chem., 65, 2022
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7WCX
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![BU of 7wcx by Molmil](/molmil-images/mine/7wcx) | Crystal structure of FGFR4(V550M) kinase domain with 7v | Descriptor: | Fibroblast growth factor receptor 4, SULFATE ION, ~{N}-[2-[[5-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1~{H}-indazol-3-yl]amino]-3-fluoranyl-5-(4-morpholin-4-ylpiperidin-1-yl)phenyl]propanamide | Authors: | Chen, X.J, Lin, Q.M, Dai, S.Y, Chen, Y.H. | Deposit date: | 2021-12-20 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.175 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives as Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4. J.Med.Chem., 65, 2022
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7BZJ
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![BU of 7bzj by Molmil](/molmil-images/mine/7bzj) | The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors | Descriptor: | Leucine--tRNA ligase, [(1~{R},5~{R},6~{S},8~{R})-8-(6-aminopurin-9-yl)-4'-[(~{R})-oxidanyl-[4-(2-oxidanylidenepropylsulfanyl)phenyl]methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,7'-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-6-yl]methoxy-tris(oxidanyl)phosphanium | Authors: | Liu, R.J, Li, H, Wang, E.D, Zhou, H. | Deposit date: | 2020-04-28 | Release date: | 2020-12-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. Bioorg.Med.Chem., 29, 2021
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7YTU
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![BU of 7ytu by Molmil](/molmil-images/mine/7ytu) | |
7YTT
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![BU of 7ytt by Molmil](/molmil-images/mine/7ytt) | |
7BP3
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![BU of 7bp3 by Molmil](/molmil-images/mine/7bp3) | Cryo-EM structure of the human MCT2 | Descriptor: | Monocarboxylate transporter 2 | Authors: | Zhang, B, Jin, Q, Zhang, X, Guo, J, Ye, S. | Deposit date: | 2020-03-21 | Release date: | 2020-06-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cooperative transport mechanism of human monocarboxylate transporter 2. Nat Commun, 11, 2020
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7E93
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![BU of 7e93 by Molmil](/molmil-images/mine/7e93) | Intact TRAPPII (state III). | Descriptor: | TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, Trafficking protein particle complex II-specific subunit 130, ... | Authors: | Mi, C.C, Sui, S.F. | Deposit date: | 2021-03-03 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (6.54 Å) | Cite: | Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32. Sci Adv, 8, 2022
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7E8T
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![BU of 7e8t by Molmil](/molmil-images/mine/7e8t) | Monomer of Ypt32-TRAPPII | Descriptor: | GTP-binding protein YPT32/YPT11, TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, ... | Authors: | Mi, C.C, Sui, S.F. | Deposit date: | 2021-03-02 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32. Sci Adv, 8, 2022
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7E94
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![BU of 7e94 by Molmil](/molmil-images/mine/7e94) | Intact TRAPPII (State II) | Descriptor: | TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, Trafficking protein particle complex II-specific subunit 130, ... | Authors: | Mi, C.C, Sui, S.F. | Deposit date: | 2021-03-03 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.67 Å) | Cite: | Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32. Sci Adv, 8, 2022
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7E2C
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![BU of 7e2c by Molmil](/molmil-images/mine/7e2c) | Monomer of TRAPPII (open) | Descriptor: | TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, Trafficking protein particle complex II-specific subunit 130, ... | Authors: | Sui, S.F, Sun, S, Mi, C.C. | Deposit date: | 2021-02-05 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32. Sci Adv, 8, 2022
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7E8S
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![BU of 7e8s by Molmil](/molmil-images/mine/7e8s) | Intact TRAPPII (state I). | Descriptor: | TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, Trafficking protein particle complex II-specific subunit 130, ... | Authors: | Mi, C.C, Sui, S.F. | Deposit date: | 2021-03-02 | Release date: | 2022-02-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.36 Å) | Cite: | Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32. Sci Adv, 8, 2022
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