7DFW

Cryo_EM structure of delta N-NPC1L1-CLR

Summary for 7DFW

• Entry DOI: 10.2210/pdb7dfw/pdb
• EMDB information: 30666
• Descriptor: NPC1-like intracellular cholesterol transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: cholesterol, structural protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 148062.60

Authors

Hu, M.,Sun, S. (deposition date: 2020-11-10, release date: 2021-08-11)

• Primary citation: Hu, M.,Yang, F.,Huang, Y.,You, X.,Liu, D.,Sun, S.,Sui, S.F.; Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.; Sci Adv, 7:-, 2021; PubMed: 34272236; DOI: 10.1126/sciadv.abg3188

Experimental method

ELECTRON MICROSCOPY (2.69 Å)