7DFW
Cryo_EM structure of delta N-NPC1L1-CLR
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 823 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU22-SER284 | |
| A | THR373-ASP632 | |
| A | SER688-LEU696 | |
| A | THR764-SER776 | |
| A | SER868-LEU1139 | |
| A | ALA1190-ILE1191 | |
| A | LEU1258-ASP1268 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU285-PHE305 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 159 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | ARG306-TRP351 | |
| A | TYR654-ALA666 | |
| A | VAL718-ARG742 | |
| A | ASP798-ARG846 | |
| A | ILE1161-LEU1168 | |
| A | PHE1213-GLN1236 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | PRO352-PHE372 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU633-SER653 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | THR667-PHE687 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL697-PHE717 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL743-LEU763 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY777-LEU797 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY847-ILE867 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU1140-GLY1160 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE1169-PHE1189 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER1192-VAL1212 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE1237-PHE1257 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=13 => ECO:0000255 |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21525977 |
| Chain | Residue | Details |
| A | ASN54 | |
| A | ASN138 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN132 | |
| A | ASN244 | |
| A | ASN416 | |
| A | ASN431 | |
| A | ASN464 | |
| A | ASN479 | |
| A | ASN497 | |
| A | ASN506 | |
| A | ASN626 |
