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4R7M
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BU of 4r7m by Molmil
Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor
Descriptor: 4-amino-N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}benzamide, CARBONATE ION, DIMETHYL SULFOXIDE, ...
Authors:Drinkwater, N, Mcgowan, S.
Deposit date:2014-08-28
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors.
J.Med.Chem., 57, 2014
3CVS
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BU of 3cvs by Molmil
Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Adenine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(8OG)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DAP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-19
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
8HBS
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BU of 8hbs by Molmil
Crystal of rAlfNmt
Descriptor: Glycylpeptide N-tetradecanoyltransferase
Authors:Wang, Y, Wang, S.
Deposit date:2022-10-30
Release date:2023-03-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:N -Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus.
Microbiol Spectr, 11, 2023
3CVT
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BU of 3cvt by Molmil
Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*(8OG)P*DAP*DGP*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-19
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3CWS
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BU of 3cws by Molmil
Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxyinosine:Thymine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FI)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DTP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-22
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3CWU
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BU of 3cwu by Molmil
Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxy-1,N6-ethenoadenine:Thymine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FE)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DTP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-22
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
1BQJ
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BU of 1bqj by Molmil
CRYSTAL STRUCTURE OF D(ACCCT)
Descriptor: DNA (5'-D(*AP*CP*CP*CP*T)-3')
Authors:Weil, J, Min, T, Yang, C, Wang, S, Sutherland, C, Sinha, N, Kang, C.H.
Deposit date:1998-08-17
Release date:1999-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT).
Acta Crystallogr.,Sect.D, 55, 1999
3CWA
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BU of 3cwa by Molmil
Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair
Descriptor: DNA (5'-D(*(8OG)P*DAP*DCP*DAP*DTP*DGP*DAP*DGP*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-21
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3D4V
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BU of 3d4v by Molmil
Crystal Structure of an AlkA Host/Guest Complex N7MethylGuanine:Cytosine Base Pair
Descriptor: 5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(FMG)P*DTP*DGP*DCP*DC)-3', 5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3', DNA-3-methyladenine glycosylase 2
Authors:Lee, S, Bowman, B.R, Wang, S, Verdine, G.L.
Deposit date:2008-05-15
Release date:2008-09-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.
J.Am.Chem.Soc., 130, 2008
6NVB
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BU of 6nvb by Molmil
Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
Descriptor: GLYCEROL, Kallikrein-4, SULFATE ION
Authors:Riley, B.T, Buckle, A.M, McGowan, S.
Deposit date:2019-02-04
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.636 Å)
Cite:Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.
Acta Crystallogr.,Sect.F, 75, 2019
5WSO
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BU of 5wso by Molmil
crystal structure of BVDV NS3 helicase
Descriptor: NS3 helicase
Authors:Li, P, Shi, J, Wang, S, Li, S, Mao, X.
Deposit date:2016-12-08
Release date:2017-12-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Crystal structure of BVDV NS3 helicase
To Be Published
1X7D
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BU of 1x7d by Molmil
Crystal Structure Analysis of Ornithine Cyclodeaminase Complexed with NAD and ornithine to 1.6 Angstroms
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-ornithine, ...
Authors:Alam, S, Goodman, J.L, Wang, S, Ruzicka, F.J, Frey, P.A, Wedekind, J.E.
Deposit date:2004-08-13
Release date:2004-11-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Ornithine Cyclodeaminase: Structure, Mechanism of Action, and Implications for the u-Crystallin Family
Biochemistry, 43, 2004
5XBL
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BU of 5xbl by Molmil
Structure of nuclease in complex with associated protein
Descriptor: Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER)
Authors:Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z.
Deposit date:2017-03-20
Release date:2017-06-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature, 546, 2017
5UK6
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BU of 5uk6 by Molmil
Structure of Anabaena Sensory Rhodopsin Determined by Solid State NMR Spectroscopy and DEER
Descriptor: Bacteriorhodopsin
Authors:Milikisiyants, S, Wang, S, Munro, R.A, Donohue, M, Ward, M.E, Brown, L.S, Smirnova, T.I, Ladizhansky, V, Smirnov, A.I.
Deposit date:2017-01-20
Release date:2017-05-31
Last modified:2020-01-08
Method:SOLID-STATE NMR
Cite:Oligomeric Structure of Anabaena Sensory Rhodopsin in a Lipid Bilayer Environment by Combining Solid-State NMR and Long-range DEER Constraints.
J. Mol. Biol., 429, 2017
7T3V
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BU of 7t3v by Molmil
Metal dependent activation of Plasmodium falciparum M17 aminopeptidase, spacegroup P22121 after crystals soaked with Zn2+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CARBONATE ION, M17 leucyl aminopeptidase, ...
Authors:Webb, C.T, McGowan, S.
Deposit date:2021-12-08
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase.
J.Biol.Chem., 298, 2022
3CW7
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BU of 3cw7 by Molmil
Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(8OG)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-21
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3CWT
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BU of 3cwt by Molmil
Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxyinosine:Adenine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FI)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DAP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-22
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
7SRV
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BU of 7srv by Molmil
Metal dependent activation of Plasmodium falciparum M17 aminopeptidase (inactive form), spacegroup P22121
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Webb, C.T, McGowan, S.
Deposit date:2021-11-08
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase.
J.Biol.Chem., 298, 2022
1CN0
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BU of 1cn0 by Molmil
CRYSTAL STRUCTURE OF D(ACCCT)
Descriptor: DNA (5'-D(*AP*CP*CP*CP*T)-3')
Authors:Weil, J, Min, T, Cheng, Y, Wang, S, Sutherland, C, Sinha, N, Kang, C.
Deposit date:1999-05-24
Release date:2000-05-24
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT).
Acta Crystallogr.,Sect.D, 55, 1999
3QYC
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BU of 3qyc by Molmil
Structure of a dimeric anti-HER2 single domain antibody
Descriptor: VH domain of IgG molecule
Authors:Baral, T.N, Chao, S, Li, S, Tanha, J, Arbabai, M, Wang, S, Zhang, J.
Deposit date:2011-03-03
Release date:2012-02-08
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of a Human Single Domain Antibody Dimer Formed through V(H)-V(H) Non-Covalent Interactions.
Plos One, 7, 2012
4QY8
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BU of 4qy8 by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.353 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
4R1C
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BU of 4r1c by Molmil
Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
Descriptor: Apical membrane antigen 1, AMA1
Authors:Lim, S.S, Norton, R.S, McGowan, S.
Deposit date:2014-08-04
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
6K3H
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BU of 6k3h by Molmil
Crystallographic Analysis of Nucleoside Diphosphate Kinase (NDK) from Aspergillus Flavus
Descriptor: Nucleoside diphosphate kinase
Authors:Wang, Y, Wang, S, Wang, S.H.
Deposit date:2019-05-18
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungusAspergillus flavus.
J.Biol.Chem., 294, 2019
4QXA
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BU of 4qxa by Molmil
Crystal structure of the Rab9A-RUTBC2 RBD complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-9A, ...
Authors:Zhang, Z, Wang, S, Ding, J.
Deposit date:2014-07-19
Release date:2014-09-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2.
Structure, 22, 2014
4QYO
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BU of 4qyo by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
Descriptor: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
Authors:Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
Deposit date:2014-07-24
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.208 Å)
Cite:Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015

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