3D4V
Crystal Structure of an AlkA Host/Guest Complex N7MethylGuanine:Cytosine Base Pair
Summary for 3D4V
Entry DOI | 10.2210/pdb3d4v/pdb |
Descriptor | DNA-3-methyladenine glycosylase 2, 5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(FMG)P*DTP*DGP*DCP*DC)-3', 5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3', ... (4 entities in total) |
Functional Keywords | alka, n7methylguanine, dna repair, host-guest complex, dna structure, dna damage, hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Escherichia coli |
Total number of polymer chains | 8 |
Total formula weight | 140418.59 |
Authors | Lee, S.,Bowman, B.R.,Wang, S.,Verdine, G.L. (deposition date: 2008-05-15, release date: 2008-09-09, Last modification date: 2024-02-21) |
Primary citation | Lee, S.,Bowman, B.R.,Ueno, Y.,Wang, S.,Verdine, G.L. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J.Am.Chem.Soc., 130:11570-11571, 2008 Cited by PubMed: 18686953DOI: 10.1021/ja8025328 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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