7SMM
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![BU of 7smm by Molmil](/molmil-images/mine/7smm) | Cryo-EM structure of Torpedo acetylcholine receptor in apo form | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMR
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![BU of 7smr by Molmil](/molmil-images/mine/7smr) | Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMQ
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![BU of 7smq by Molmil](/molmil-images/mine/7smq) | Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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6LCI
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![BU of 6lci by Molmil](/molmil-images/mine/6lci) | Solution structure of mdaA-1 domain | Descriptor: | mdaA-1 | Authors: | Nguyen, T.A, Le, S, Lee, M, Fan, J.S, Yang, D, Yan, J, Jedd, G. | Deposit date: | 2019-11-19 | Release date: | 2020-11-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Fungal Wound Healing through Instantaneous Protoplasmic Gelation. Curr.Biol., 31, 2021
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7SMS
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![BU of 7sms by Molmil](/molmil-images/mine/7sms) | Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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7SMT
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![BU of 7smt by Molmil](/molmil-images/mine/7smt) | Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | Deposit date: | 2021-10-26 | Release date: | 2022-03-09 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29, 2022
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6LOP
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![BU of 6lop by Molmil](/molmil-images/mine/6lop) | Crystal Structure of Class IB terpene synthase bound with geranylgeraniol | Descriptor: | (2~{E},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol, Tetraprenyl-beta-curcumene synthase | Authors: | Fujihashi, M, Inagi, H, Miki, K. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Characterization of Class IB Terpene Synthase: The First Crystal Structure Bound with a Substrate Surrogate. Acs Chem.Biol., 15, 2020
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6MDC
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![BU of 6mdc by Molmil](/molmil-images/mine/6mdc) | Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Pyrazolo-pyrimidinone 1 SHP389 | Descriptor: | 6-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-[3-chloro-2-(cyclopropylamino)pyridin-4-yl]-5-methyl-2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Fodor, M, Stams, T. | Deposit date: | 2018-09-04 | Release date: | 2019-02-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. J. Med. Chem., 62, 2019
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6LL8
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![BU of 6ll8 by Molmil](/molmil-images/mine/6ll8) | Type II inorganic pyrophosphatase (PPase) from the psychrophilic bacterium Shewanella sp. AS-11, Mg-PNP form | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, FLUORIDE ION, ... | Authors: | Horitani, M, Kusubayashi, K, Oshima, K, Yato, A, Sugimoto, H, Watanabe, K. | Deposit date: | 2019-12-21 | Release date: | 2020-03-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase. Sci Rep, 10, 2020
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6LLG
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![BU of 6llg by Molmil](/molmil-images/mine/6llg) | Crystal Structure of Fagopyrum esculentum M UGT708C1 | Descriptor: | BENZAMIDINE, SULFATE ION, UDP-glycosyltransferase 708C1 | Authors: | Wang, X, Liu, M. | Deposit date: | 2019-12-23 | Release date: | 2020-09-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of theC-Glycosyltransferase UGT708C1 from Buckwheat Provide Insights into the Mechanism ofC-Glycosylation. Plant Cell, 32, 2020
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7S2S
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![BU of 7s2s by Molmil](/molmil-images/mine/7s2s) | nanobody bound to Interleukin-2Rbeta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ... | Authors: | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | Deposit date: | 2021-09-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
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7S2R
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![BU of 7s2r by Molmil](/molmil-images/mine/7s2r) | nanobody bound to IL-2Rg | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | Authors: | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | Deposit date: | 2021-09-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
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6LQH
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![BU of 6lqh by Molmil](/molmil-images/mine/6lqh) | High resolution architecture of curli complex | Descriptor: | Curli production assembly/transport component CsgF, Curli production assembly/transport component CsgG | Authors: | Zhang, M, Shi, H, Huang, Y. | Deposit date: | 2020-01-13 | Release date: | 2020-07-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae. Plos Biol., 18, 2020
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7SEZ
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![BU of 7sez by Molmil](/molmil-images/mine/7sez) | Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with m7GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, SODIUM ION | Authors: | Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D. | Deposit date: | 2021-10-02 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.70001245 Å) | Cite: | Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis. Structure, 30, 2022
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7SF0
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![BU of 7sf0 by Molmil](/molmil-images/mine/7sf0) | Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with trinucleotide substrate | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, MAGNESIUM ION, ... | Authors: | Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D. | Deposit date: | 2021-10-02 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95000446 Å) | Cite: | Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis. Structure, 30, 2022
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6LTU
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![BU of 6ltu by Molmil](/molmil-images/mine/6ltu) | Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket | Descriptor: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6LQJ
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![BU of 6lqj by Molmil](/molmil-images/mine/6lqj) | Low resolution architecture of curli complex | Descriptor: | Curli production assembly/transport component CsgF, Curli production assembly/transport component CsgG | Authors: | Zhang, M, Shi, H, Huang, Y. | Deposit date: | 2020-01-13 | Release date: | 2020-07-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae. Plos Biol., 18, 2020
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6LS4
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![BU of 6ls4 by Molmil](/molmil-images/mine/6ls4) | A novel anti-tumor agent S-40 in complex with tubulin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | Authors: | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | Deposit date: | 2020-01-17 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Lett., 495, 2020
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6LK3
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![BU of 6lk3 by Molmil](/molmil-images/mine/6lk3) | The Functional Characterization and Crystal Structure of Type II Peptidyl Carrier Protein ColA1a in Collismycins Biosynthesis | Descriptor: | Putative free-standing acyl carrier protein | Authors: | Ma, X.Y, Wang, G.Y, Liu, T, Chi, C.B, Zhang, Z.Y, Yang, D.H, Liu, W, Ma, M. | Deposit date: | 2019-12-18 | Release date: | 2020-10-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The functional characterization and crystal structure of type II peptidyl carrier protein ColA1a in collismycins biosynthesis. Chin.J.Chem., 38, 2020
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6LKD
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![BU of 6lkd by Molmil](/molmil-images/mine/6lkd) | in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor | Descriptor: | 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Mimasu, S, Yamagishi, H, Kiyohara, M, Kakefuda, K, Okuda, T. | Deposit date: | 2019-12-19 | Release date: | 2020-12-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4, 2021
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6LKT
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![BU of 6lkt by Molmil](/molmil-images/mine/6lkt) | Crystal structure of the Fab fragment of murine monoclonal antibody KH-1 against Human herpesvirus 6B | Descriptor: | antibody Fab Fragment L-chain, antibody Fab fragment H chain | Authors: | Nishimura, M, Novita, B.D, Kato, T, Tjan, L.H, Wang, B, Wakata, A, Poetranto, A.L, Kawabata, A, Tang, H, Aoshi, T, Mori, Y. | Deposit date: | 2019-12-20 | Release date: | 2020-06-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134. Plos Pathog., 16, 2020
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6LLZ
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![BU of 6llz by Molmil](/molmil-images/mine/6llz) | |
6M0S
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![BU of 6m0s by Molmil](/molmil-images/mine/6m0s) | 3.6A Yeast Vo state3 prime | Descriptor: | Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | Authors: | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, SIngharoy, A, Chiu, W. | Deposit date: | 2020-02-22 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
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7RYN
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![BU of 7ryn by Molmil](/molmil-images/mine/7ryn) | CD1a-sulfatide-gdTCR complex | Descriptor: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wegrecki, M, Le Nours, J, Rossjohn, J. | Deposit date: | 2021-08-25 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
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7SCW
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![BU of 7scw by Molmil](/molmil-images/mine/7scw) | KRAS full length wild-type in complex with RGL1 Ras association domain | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | Authors: | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | Deposit date: | 2021-09-29 | Release date: | 2022-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant. J.Mol.Biol., 434, 2022
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