8IP4
 
 | | Cryo-EM structure of hMRS-highEDTA | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | Deposit date: | 2023-03-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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8IP5
 | | Cryo-EM structure of hMRS2-lowEDTA | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | Deposit date: | 2023-03-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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8IP6
 | | Cryo-EM structure of hMRS2-rest | | Descriptor: | CHLORIDE ION, Magnesium transporter MRS2 homolog, mitochondrial | | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | Deposit date: | 2023-03-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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8IP3
 | | Cryo-EM structure of hMRS2-Mg | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | Deposit date: | 2023-03-14 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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4R3Q
 | | Crystal structure of SYCE3 | | Descriptor: | Synaptonemal complex central element protein 3 | | Authors: | Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y. | | Deposit date: | 2014-08-17 | | Release date: | 2014-11-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Structural insight into the central element assembly of the synaptonemal complex
Sci Rep, 4, 2014
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7F6V
 | | Cryo-EM structure of the human TACAN channel in a closed state | | Descriptor: | CHOLESTEROL, Ion channel TACAN | | Authors: | Chen, X.Z, Wang, Y.J, Li, Y, Yang, X, Shen, Y.Q. | | Deposit date: | 2021-06-25 | | Release date: | 2022-02-16 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Cryo-EM structure of the human TACAN in a closed state.
Cell Rep, 38, 2022
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6AKI
 | | Calcium release-activated calcium channel protein 1, P288L mutant | | Descriptor: | CHLORIDE ION, Calcium release-activated calcium channel protein 1 | | Authors: | Liu, X, Wu, G, Yang, X, Shen, Y. | | Deposit date: | 2018-09-01 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (4.496 Å) | | Cite: | Calcium release-activated calcium channel protein 1, P288L mutant
To Be Published
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5X5Y
 | | A membrane protein complex | | Descriptor: | Probable ATP-binding component of ABC transporter, Uncharacterized protein | | Authors: | Luo, Q, Yang, X, Huang, Y. | | Deposit date: | 2017-02-18 | | Release date: | 2017-04-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.465 Å) | | Cite: | Structural basis for lipopolysaccharide extraction by ABC transporter LptB2FG
Nat. Struct. Mol. Biol., 24, 2017
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3BV6
 | | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold | | Descriptor: | FE (III) ION, Metal-dependent hydrolase | | Authors: | Minasov, G, Shuvalova, L, Brunzelle, J.S, Yang, X, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-01-04 | | Release date: | 2008-01-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold.
To be Published
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8JI8
 | | Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | | Authors: | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | | Deposit date: | 2023-05-26 | | Release date: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Mosquitoes have evolved two types of prophenoloxidases
To Be Published
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7CAF
 | | Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAG
 | | Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAD
 | | Mycobacterium smegmatis SugABC complex | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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3FGQ
 | | Crystal structure of native human neuroserpin | | Descriptor: | GLYCEROL, Neuroserpin | | Authors: | Takehara, S, Yang, X, Mikami, B, Onda, M. | | Deposit date: | 2008-12-08 | | Release date: | 2009-04-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability
J.Mol.Biol., 388, 2009
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7CAE
 | | Mycobacterium smegmatis LpqY-SugABC complex in the resting state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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5XJO
 | | Plant receptor ERL1-TMM in complex with peptide EPF1 | | Descriptor: | LRR receptor-like serine/threonine-protein kinase ERL1, Protein EPIDERMAL PATTERNING FACTOR 1, Protein TOO MANY MOUTHS | | Authors: | Chai, J, Lin, G, Zhang, L, Han, Z, Shpak, E.D, Yang, X. | | Deposit date: | 2017-05-03 | | Release date: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (2.626 Å) | | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
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7DD5
 | | Structure of Calcium-Sensing Receptor in complex with NPS-2143 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | | Authors: | Wen, T.L, Yang, X, Shen, Y.Q. | | Deposit date: | 2020-10-27 | | Release date: | 2021-06-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor.
Sci Adv, 7, 2021
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7DD7
 | | Structure of Calcium-Sensing Receptor in complex with Evocalcet | | Descriptor: | 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wen, T.L, Yang, X, Shen, Y.Q. | | Deposit date: | 2020-10-27 | | Release date: | 2021-06-16 | | Last modified: | 2021-06-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor.
Sci Adv, 7, 2021
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7DD6
 | | Structure of Ca2+/L-Trp-bonnd Calcium-Sensing Receptor in active state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Wen, T.L, Yang, X, Shen, Y.Q. | | Deposit date: | 2020-10-27 | | Release date: | 2021-06-16 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor.
Sci Adv, 7, 2021
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5Z9Y
 | | Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | | Descriptor: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | | Authors: | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | | Deposit date: | 2018-02-05 | | Release date: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
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5XGI
 | | Crystal structure of PI3K complex with an inhibitor | | Descriptor: | 3-azanyl-5-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | Authors: | Song, K, Yang, X, Zhao, Y, Jian, Z. | | Deposit date: | 2017-04-13 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Crystal structure of PI3K complex with an inhibitor
To Be Published
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5XJX
 | | Pre-formed plant receptor ERL1-TMM complex | | Descriptor: | LRR receptor-like serine/threonine-protein kinase ERL1, Protein TOO MANY MOUTHS | | Authors: | Chai, J, Lin, G, Zhang, L, Han, Z, Yang, X, Liu, W, Qi, Y, Chang, J, Li, E. | | Deposit date: | 2017-05-04 | | Release date: | 2019-01-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.055 Å) | | Cite: | A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
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7WL5
 | | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Wei, X, Yang, X, Chen, Q, Meng, G. | | Deposit date: | 2022-01-12 | | Release date: | 2023-01-18 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1)
To Be Published
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5XGJ
 | | Crystal structure of PI3K complex with an inhibitor | | Descriptor: | 3-(4-morpholin-4-ylfuro[3,2-d]pyrimidin-2-yl)-5-[(phenylmethyl)amino]phenol, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, ... | | Authors: | Song, K, Yang, X, Zhao, Y, Jian, Z. | | Deposit date: | 2017-04-13 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Crystal structure of PI3K complex with an inhibitor
To Be Published
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6D1W
 | | human PKD2 F604P mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | | Authors: | Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E. | | Deposit date: | 2018-04-12 | | Release date: | 2018-06-27 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
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