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2J1K
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BU of 2j1k by Molmil
CAV-2 fibre head in complex with CAR D1
Descriptor: COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN
Authors:Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S.
Deposit date:2006-08-14
Release date:2006-09-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
2IYK
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BU of 2iyk by Molmil
Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION
Authors:Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S.
Deposit date:2006-07-18
Release date:2006-08-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1.
RNA, 12, 2006
2J12
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BU of 2j12 by Molmil
Ad37 fibre head in complex with CAR D1
Descriptor: CALCIUM ION, COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN
Authors:Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S.
Deposit date:2006-08-08
Release date:2006-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
2I4O
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BU of 2i4o by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
4CB7
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BU of 4cb7 by Molmil
Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8e)
Descriptor: 5-[2-(2-azanyl-7-methyl-6-oxidanylidene-1H-purin-9-ium-9-yl)ethanoyl]-2-oxidanyl-benzoic acid, GLYCEROL, POLYMERASE BASIC SUBUNIT 2
Authors:Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S.
Deposit date:2013-10-10
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
4CB5
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BU of 4cb5 by Molmil
Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8f)
Descriptor: 9-N-(3-CARBOXY-4-HYDROXYPHENYL)KETOMETHYL-7-N-METHYLGUANINE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2
Authors:Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S.
Deposit date:2013-10-10
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
4CB6
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BU of 4cb6 by Molmil
Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11)
Descriptor: 2,9-N,N-DI(4-CARBOXYBUTYL)-7-N-METHYLGUANINE, IODIDE ION, POLYMERASE BASIC SUBUNIT 2
Authors:Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S.
Deposit date:2013-10-10
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
4CB4
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BU of 4cb4 by Molmil
Structure of Influenza A H5N1 PB2 cap-binding domain with bound m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2
Authors:Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S.
Deposit date:2013-10-10
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
2I4L
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BU of 2i4l by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase
Descriptor: Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4N
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BU of 2i4n by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with CysAMS
Descriptor: 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4M
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BU of 2i4m by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
4CKB
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BU of 4ckb by Molmil
Vaccinia virus capping enzyme complexed with GTP and SAH
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MRNA-CAPPING ENZYME CATALYTIC SUBUNIT, MRNA-CAPPING ENZYME REGULATORY SUBUNIT, ...
Authors:Kyrieleis, O.J.P, Chang, J, de la Pena, M, Shuman, S, Cusack, S.
Deposit date:2014-01-02
Release date:2014-03-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Vaccinia Virus Mrna Capping Enzyme Provides Insights Into the Mechanism and Evolution of the Capping Apparatus.
Structure, 22, 2014
4D25
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BU of 4d25 by Molmil
Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA and AMPPNP
Descriptor: 5'-R(*UP*GP*AP*CP*AP*UP)-3', BMVLG PROTEIN, GLYCEROL, ...
Authors:Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S.
Deposit date:2014-05-07
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts.
Cell(Cambridge,Mass.), 157, 2014
4D26
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BU of 4d26 by Molmil
Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA,ADP and Pi
Descriptor: 5'-R(*UP*GP*AP*CP*AP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, BMVLG PROTEIN, ...
Authors:Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S.
Deposit date:2014-05-07
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts.
Cell(Cambridge,Mass.), 157, 2014
1EAJ
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BU of 1eaj by Molmil
DIMERIC STRUCTURE OF THE COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR D1 DOMAIN AT 1.35 ANGSTROM RESOLUTION
Descriptor: COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR, SULFATE ION
Authors:van Raaij, M.J, Cusack, S.
Deposit date:2001-07-12
Release date:2001-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.
Structure, 8, 2000
1F5W
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BU of 1f5w by Molmil
DIMERIC STRUCTURE OF THE COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR D1 DOMAIN
Descriptor: COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR, SULFATE ION
Authors:van Raaij, M.J, Chouin, E, van der Zandt, H, Bergelson, J.M, Cusack, S.
Deposit date:2000-06-18
Release date:2000-11-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.
Structure Fold.Des., 8, 2000
2V9T
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BU of 2v9t by Molmil
Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
Descriptor: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2XGT
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BU of 2xgt by Molmil
Asparaginyl-tRNA synthetase from Brugia malayi complexed with the sulphamoyl analogue of asparaginyl-adenylate
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, ...
Authors:Crepin, T, Haertlein, M, Kron, M, Cusack, S.
Deposit date:2010-06-07
Release date:2010-12-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
2V9Q
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BU of 2v9q by Molmil
First and second Ig domains from human Robo1
Descriptor: MERCURY (II) ION, ROUNDABOUT HOMOLOG 1
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9S
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BU of 2v9s by Molmil
Second LRR domain of human Slit2
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2014-11-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
1H7Z
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BU of 1h7z by Molmil
Adenovirus Ad3 fibre head
Descriptor: ADENOVIRUS FIBRE PROTEIN, SULFATE ION
Authors:Durmort, C, Stehlin, C, Schoehn, G, Mitraki, A, Drouet, E, Cusack, S, Burmeister, W.P.
Deposit date:2001-01-21
Release date:2001-07-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Fiber Head of Ad3, a Non-Car-Binding Serotype of Adenovirus
Virology, 285, 2001
1H6K
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BU of 1h6k by Molmil
nuclear Cap Binding Complex
Descriptor: 20 KDA NUCLEAR CAP BINDING PROTEIN, CBP80
Authors:Mazza, C, Ohno, M, Segref, A, Mattaj, I.W, Cusack, S.
Deposit date:2001-06-18
Release date:2001-09-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Nuclear CAP Binding Complex
Mol.Cell, 8, 2001
2XTI
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BU of 2xti by Molmil
Asparaginyl-tRNA synthetase from Brugia malayi complexed with ATP:Mg and L-Asp-beta-NOH adenylate:PPi:Mg
Descriptor: 5'-O-[(R)-{[(2S)-2-amino-4-(hydroxyamino)-4-oxobutanoyl]oxy}(hydroxy)phosphoryl]adenosine, ADENOSINE-5'-TRIPHOSPHATE, ASPARAGINYL-TRNA SYNTHETASE, ...
Authors:Crepin, T, Haertlein, M, Kron, M, Cusack, S.
Deposit date:2010-10-10
Release date:2010-12-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
2V9R
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BU of 2v9r by Molmil
First and second Ig domains from human Robo1 (Form 2)
Descriptor: ROUNDABOUT HOMOLOG 1, SULFATE ION
Authors:Morlot, C, Cusack, S, McCarthy, A.A.
Deposit date:2007-08-25
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
6FHH
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BU of 6fhh by Molmil
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated.
Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Lukarska, M, Cusack, S.
Deposit date:2018-01-14
Release date:2019-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain
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