8SVM
Plasmodium falciparum M17 aminopeptidase bound to MMV1557817
Summary for 8SVM
Entry DOI | 10.2210/pdb8svm/pdb |
Related | 8SVL |
Descriptor | Leucine aminopeptidase, CARBONATE ION, ZINC ION, ... (7 entities in total) |
Functional Keywords | metallo-exopeptidase; protease inhibitor, malaria, plasmodium, m17 aminopeptidase, hydrolase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Total number of polymer chains | 12 |
Total formula weight | 719354.80 |
Authors | |
Primary citation | de Koning-Ward, T.F.,Drinkwater, N.,Edgar, R.C.S.,McGowan, S.,Scammells, P.J. Characterisation of a novel antimalarial agent targeting haemaglobin digestion that shows cross-species reactivity and excellent in vivo properties. Mbio, 2024 |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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