8SVM
Plasmodium falciparum M17 aminopeptidase bound to MMV1557817
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Leucine aminopeptidase | polymer | 528 | 58709.0 | 12 | UniProt (Q8IL11) Pfam (PF00883) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | PfLAP,M17 leucyl aminopeptidase,PfA-M17,PfM17LAP |
2 | C, J, G, K, D... | CARBONATE ION | non-polymer | 60.0 | 12 | Chemie (CO3) | |||
3 | F, C, J, G, K... | ZINC ION | non-polymer | 65.4 | 24 | Chemie (ZN) | |||
4 | F, C, J, G, K... | N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-3,3-dimethylbutanamide | non-polymer | 394.4 | 12 | Chemie (WRC) | |||
5 | B, I, F, C, J... | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 28 | Chemie (1PE) | |||
6 | F, J, C, G, K... | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
7 | water | water | 18.0 | 3033 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)
PDB | External Database | Details |
---|---|---|
Gln 152 | Asn 152 | engineered mutation |
Gln 515 | Asn 515 | engineered mutation |
Gln 546 | Asn 546 | engineered mutation |
His 606 | - | expression tag |
His 607 | - | expression tag |
His 608 | - | expression tag |
His 609 | - | expression tag |
His 610 | - | expression tag |
His 611 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 704507.7 | |
Non-Polymers* | Number of molecules | 88 |
Total formula weight | 14847.1 | |
All* | Total formula weight | 719354.8 |