7USE
Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site
Summary for 7USE
Entry DOI | 10.2210/pdb7use/pdb |
EMDB information | 26734 |
Descriptor | Cytoplasmic FMR1-interacting protein 1, GUANOSINE-5'-TRIPHOSPHATE, Nck-associated protein 1, ... (10 entities in total) |
Functional Keywords | actin regulator, gtpase binding protein, cytoskeletal regulator, cell invasion |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 381242.21 |
Authors | Ding, B.,Yang, S.,Chen, B.,Chowdhury, S. (deposition date: 2022-04-25, release date: 2022-09-21, Last modification date: 2024-06-12) |
Primary citation | Ding, B.,Yang, S.,Schaks, M.,Liu, Y.,Brown, A.J.,Rottner, K.,Chowdhury, S.,Chen, B. Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nat Commun, 13:5444-5444, 2022 Cited by PubMed: 36114192DOI: 10.1038/s41467-022-33174-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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