7D7S
HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant
Summary for 7D7S
Entry DOI | 10.2210/pdb7d7s/pdb |
Related | 3H0F 3H0H 3H0I 4d8d 6IPY 6IPZ |
Descriptor | Protein Nef, Tyrosine-protein kinase Fyn (2 entities in total) |
Functional Keywords | complex, mutant, kinase, sh3, viral protein |
Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) (HIV-1) More |
Total number of polymer chains | 4 |
Total formula weight | 67681.65 |
Authors | Aldehaiman, A.,Shahul Hamed, U.F.,Arold, S.T. (deposition date: 2020-10-05, release date: 2020-11-18, Last modification date: 2023-11-29) |
Primary citation | Aldehaiman, A.,Momin, A.A.,Restouin, A.,Wang, L.,Shi, X.,Aljedani, S.,Opi, S.,Lugari, A.,Shahul Hameed, U.F.,Ponchon, L.,Morelli, X.,Huang, M.,Dumas, C.,Collette, Y.,Arold, S.T. Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478:1525-1545, 2021 Cited by PubMed: 33787846DOI: 10.1042/BCJ20201002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.32 Å) |
Structure validation
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