5UPU
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the presence of TBK6
Summary for 5UPU
Entry DOI | 10.2210/pdb5upu/pdb |
Related | 4ZQM 4ZQN 4ZQO 4ZQP 4ZQR 5upv |
Descriptor | Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide, ... (4 entities in total) |
Functional Keywords | impdh, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 1 |
Total formula weight | 42282.16 |
Authors | Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Mulligan, R.,Gu, M.,Sacchettini, J.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-04, release date: 2017-02-22, Last modification date: 2023-10-04) |
Primary citation | Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Mulligan, R.,Gu, M.,Sacchettini, J.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the presence of TBK6 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.905 Å) |
Structure validation
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