5TZU

Crystal structure of human CD47 ECD bound to Fab of B6H12.2

Summary for 5TZU

• Entry DOI: 10.2210/pdb5tzu/pdb
• Related: 5TZ2 5TZT
• Descriptor: Light Chain of Fab B6H12.2, GLYCEROL, Heavy Chain of Fab B6H12.2, ... (11 entities in total)
• Functional Keywords: antigen-fab complex, immunoglobulin, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 65160.07

Authors

Cardoso, R.M.F. (deposition date: 2016-11-22, release date: 2017-03-15, Last modification date: 2020-07-29)

• Primary citation: Pietsch, E.C.,Dong, J.,Cardoso, R.,Zhang, X.,Chin, D.,Hawkins, R.,Dinh, T.,Zhou, M.,Strake, B.,Feng, P.H.,Rocca, M.,Santos, C.D.,Shan, X.,Danet-Desnoyers, G.,Shi, F.,Kaiser, E.,Millar, H.J.,Fenton, S.,Swanson, R.,Nemeth, J.A.,Attar, R.M.; Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies.; Blood Cancer J, 7:e536-e536, 2017; PubMed: 28234345; DOI: 10.1038/bcj.2017.7

Experimental method

X-RAY DIFFRACTION (2.1 Å)